ALBUTEROL SULFATE solution

দেশ: মার্কিন যুক্তরাষ্ট্র

ভাষা: ইংরেজি

সূত্র: NLM (National Library of Medicine)

সক্রিয় উপাদান:

ALBUTEROL SULFATE (UNII: 021SEF3731) (ALBUTEROL - UNII:QF8SVZ843E)

থেকে পাওয়া:

Medical Purchasing Solutions, LLC

INN (আন্তর্জাতিক নাম):

ALBUTEROL SULFATE

রচনা:

ALBUTEROL 2.5 mg in 3 mL

প্রশাসন রুট:

RESPIRATORY (INHALATION)

প্রেসক্রিপশন টাইপ:

PRESCRIPTION DRUG

থেরাপিউটিক ইঙ্গিত:

Albuterol sulfate inhalation solution is indicated for the relief of bronchospasm in patients 2 years of age and older with reversible obstructive airway disease and acute attacks of bronchospasm. Albuterol sulfate inhalation solution is contraindicated in patients with a history of hypersensitivity to any of its components. Albuterol Sulfate Inhalation Solution 0.083% 3 Note: This is a unit-dose vial. No dilution is required. Read complete instructions carefully before using. - Remove the vial from the foil pouch. - Twist the cap completely off the vial and squeeze the contents into the nebulizer reservoir (Figure 1). - Connect the nebulizer reservoir to the mouthpiece or face mask (Figure 2). - Connect the nebulizer to the compressor. - Sit in a comfortable, upright position; place the mouthpiece in your mouth (Figure 3) (or put on the face mask); and turn on the compressor. - Breathe as calmly, deeply and evenly as possible until no more mist is formed in the nebulizer chamber (ab

পণ্য সারাংশ:

Unit-dose plastic vial containing Albuterol Sulfate Inhalation Solution 0.083%, 2.5 mg/3 mL 2. Equivalent to 0.5 mL albuterol (as the sulfate) 0.5% (2.5 mg albuterol) diluted to 3 mL. Supplied in cartons as listed below. NDC 76204-200-25 25 vials per carton / 25 vials per foil pouch NDC 76204-200-30 30 vials per carton / 30 vials per foil pouch NDC 76204-200-01 30 vials per carton / 1 vial per foil pouch NDC 76204-200-60 60 vials per carton / 30 vials per foil pouch PROTECT FROM LIGHT. Store in pouch until time of use. Store between 2° and 25° C (36° and 77° F). Rx only.

অনুমোদন অবস্থা:

Abbreviated New Drug Application

পণ্য বৈশিষ্ট্য

ALBUTEROL SULFATE- ALBUTEROL SULFATE SOLUTION
MEDICAL PURCHASING SOLUTIONS, LLC
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ALBUTEROL SULFATE INHALATION SOLUTION 0.083%
1
PRESCRIBING INFORMATION
FOR INHALATION USE ONLY-NOT FOR INJECTION
DESCRIPTION
Albuterol sulfate inhalation solution is a relatively selective beta
-adrenergic
bronchodilator (see CLINICAL PHARMACOLOGY section below). Albuterol
sulfate, the
racemic form of albuterol, has the chemical name α
-[( _tert_-Butylamino)methyl]-4-
hydroxy- _m_-xylene-α,α'-diol sulfate (2:1) (salt), and the
following structural formula:
Albuterol sulfate has a molecular weight of 576.70 and the molecular
formula (C
H
NO
)
• H
SO
. Albuterol sulfate is a white or practically white powder, freely
soluble in water and slightly soluble in alcohol.
The World Health Organization recommended name for albuterol base is
salbutamol.
Albuterol sulfate inhalation solution 0.083% requires no dilution
before administration.
Each milliliter of albuterol sulfate inhalation solution 0.083%
contains 0.83 mg of albuterol
(as 1 mg of albuterol sulfate) in an isotonic, sterile, aqueous
solution containing sodium
chloride; sulfuric acid is used to adjust the pH to between 3 and 5.
Albuterol sulfate
inhalation solution 0.083% contains no sulfiting agents or
preservatives.
Albuterol sulfate inhalation solution is a clear, colorless to light
yellow solution.
CLINICAL PHARMACOLOGY
The prime action of beta-adrenergic drugs is to stimulate adenyl
cyclase, the enzyme
which catalyzes the formation of cyclic-3',5'-adenosine monophosphate
(cyclic AMP)
from adenosine triphosphate (ATP). The cyclic AMP thus formed mediates
the cellular
responses. _In vitro _studies and _in vivo _pharmacologic studies have
demonstrated that
albuterol has a preferential effect on beta
-adrenergic receptors compared with
isoproterenol. While it is recognized that beta
-adrenergic receptors are the
predominant receptors in bronchial smooth muscle, 10% to 50% of the
beta-receptors
in the human heart may be beta
-receptors. The precise function of these r