Страна: Япония
Език: английски
Източник: すりの適正使用協議会 RAD-AR Council, Japan
Pertuzumab(genetical recombination); Trastuzumab(genetical recombination); Vorhyaluronidase alfa(genetical recombination)
Chugai Pharmaceutical Co., Ltd.
Pertuzumab(genetical recombination); Trastuzumab(genetical recombination); Vorhyaluronidase alfa(genetical recombination)
injection
Drug Information Sheet("Kusuri-no-Shiori") Injection Published: 11/2023 The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment. BRAND NAME: PHESGO COMBINATION FOR SUBCUTANEOUS INJECTION MA ACTIVE INGREDIENT: Pertuzumab(genetical recombination) Trastuzumab(genetical recombination) Vorhyaluronidase alfa(genetical recombination) DOSAGE FORM: injection IMPRINT OR PRINT ON WRAPPING: EFFECTS OF THIS MEDICINE Pertuzumab (genetical recombination) and Trastuzumab (genetical recombination) suppress proliferation of cancer cells by selectively suppressing the actions of protein named HER2 necessary for proliferation of cancer cells. Vorhyaluronidase alfa (genetical recombination) increases the subcutaneous tissue permeability by hydrolyzing hyaluronic acid and promotes the drug absorption. It is usually used to treat breast cancer with HER2 positive and HER2-positive unresectable advanced or recurrent colorectal cancer progressing after cancer chemotherapy. THE FOLLOWING PATIENTS MAY NEED TO BE CAREFUL WHEN USING THIS MEDICINE.BE SURE TO TELL YOUR DOCTOR AND PHARMACIST. ・If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines or foods. If you have or have previously experienced heart disease. If you are or have previously been treated with anthracycline medicines. If you are or have previously been treated with radiation therapy to the chest. If you have or have been previously diagnosed with hypertension. ・If you are pregnant, possibly pregnant or breastfeeding. ・If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as Прочетете целия документ