Страна: САЩ
Език: английски
Източник: NLM (National Library of Medicine)
IVERMECTIN (UNII: 8883YP2R6D) (IVERMECTIN - UNII:8883YP2R6D), PYRANTEL PAMOATE (UNII: 81BK194Z5M) (PYRANTEL - UNII:4QIH0N49E7)
PetFriendly, Inc.
ORAL
PRESCRIPTION
INDICATIONS: For use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis ) for a month (30 days) after infection and for the treatment and control of ascarids (Toxocara canis , Toxoscaris leonina ) and hookworms (Ancylostoma caninum , Uncinaria stenocephala , Ancyclostoma braziliense ).
HOW SUPPLIED: Heart Defense™ is available in three dosage strengths (See DOSAGE section) for dogs of different weights. Each strength comes in convenient packs of 1 chewable tablet.
Abbreviated New Animal Drug Application
HEART DEFENSE- IVERMECTIN AND PYRANTEL PAMOATE TABLET, CHEWABLE PETFRIENDLY, INC. ---------- HEART DEFENSE™ (ivermectin/pyrantel) CHEWABLE TABLETS CAUTION: Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian. INDICATIONS: For use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (_Dirofilaria immitis_) for a month (30 days) after infection and for the treatment and control of ascarids (_Toxocara canis_, _Toxoscaris_ _leonina_) and hookworms (_Ancylostoma caninum_, _Uncinaria stenocephala_, _Ancyclostoma_ _braziliense_). DOSAGE: Heart Defense™ should be administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/Ib) of body weight. The recommended dosing schedule for prevention of canine heartworm disease and for the treatment and control of ascarids and hookworms is as follows: Dog Weight Chewable Tablets per Month Ivermectin Content Pyrantel Content Color Coding on Blister Card and Carton Up to 25 lbs. 1 68 mcg 57 mg Blue 26 to 50 lbs. 1 136 mcg 114 mg Green 51 to 100 lbs. 1 272 mcg 227 mg Brown Heart Defense™ is recommended for dogs 6 weeks of age and older. For dogs over 100 lbs, use the appropriate combination of these tablets. ADMINISTRATION: Remove only one chewable tablet at a time from the blister card. Because most dogs find Heart Defense™ palatable, the product can be offered to the dog by hand. Alternatively, it may be added intact to a small amount of dry food or placed in the back of the dog’s mouth for forced swallowing. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes after administration to ensure that part of the dose is not lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended. Heart Defense™ should be given at monthly intervals during the period of the year when m Прочетете целия документ