Страна: Малайзия
Език: английски
Източник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
PIROXICAM
HOVID BERHAD
PIROXICAM
500 Tablets; 1000 Tablets; 100 Tablets; 100Capsule Capsules
HOVID BERHAD
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ FELXICAM 20 MG CAPSULE PIROXICAM (20 MG) 1 WHAT IS IN THIS LEAFLET 1. What Felxicam is used for 2. How Felxicam works 3. Before you use Felxicam 4. How to use Felxicam 5. While you are using Felxicam 6. Side effects 7. Storage and Disposal of Felxicam 8. Product description 9. Manufacturer and Product Registration Holder 10. Date of revision 11. Serial number WHAT FELXICAM IS USED FOR To treat symptomatic relief of pain and inflammation in patients with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. However, it should not be the first choice of non- steroidal anti-inflammatory drug (NSAID) treatment in these conditions. HOW FELXICAM WORKS This medicine belongs to a group of medicines called non-steroidal anti- inflmmatory drugs (NSAIDs). NSAIDs stops the production of chemicals called prostaglandins. These chemicals are released in your body in response to illness and injury. They cause pain and inflammation (swelling) and when released in your brain may cause fever (high temperature). BEFORE YOU USE FELXICAM _- When you must not take it _ _ _ Do not take this medicine if: you are hypersensitive to piroxicam or any of the other ingredients of this product . you are hypersensitive to aspirin or any other NSAIDs medicine you are pregnant, or intend to become pregnant. you are breast-feeding or intend to breast-feed. you have or have had a peptic ulcer (ulcer of the stomach or duodenum) you have or have had inflammation of the bowel or stomach lining. Such as Crohn’s disease and ulcerative colitis you are vomiting blood you are bleeding from the rectum (back passage), have black sticky bowel motions (stools) or bloody diarrhea _ _ _- Before you start to use it_ _ _ Tell your doctor if: you are allergic to any other medicines, foods, dyes or preservatives. you are pregnant or plan to become pregnant you are breastfeeding or wish to breastfeed you have infection you plan to have surgery you ha Прочетете целия документ
DESCRIPTION FELXICAM 10 CAPSULE: Amethyst opaque/ivory opaque capsule with “HD” printed on one end and “XCM10” printed on the other end of the capsule. FELXICAM 20 CAPSULE: Amethyst opaque/amethyst opaque capsule with “HD” printed on one end and “XCM20” printed on the other end of the capsule. COMPOSITION FELXICAM 10 CAPSULE : Piroxicam 10 mg/capsule. FELXICAM 20 CAPSULE : Piroxicam 20 mg/capsule. ACTIONS AND PHARMACOLOGY Piroxicam is a non-steroidal anti-inflammatory analgesic. It has analgesic, anti-inflammmatory and anti-pyretic properties. It acts by inhibiting prostaglandin synthetase, an enzyme responsible for the synthesis of prostaglandin. PHARMACOKINETICS Piroxicam is well absorbed from the gastrointestinal tract. It is metabolized in the liver and excreted predominantly in the urine. It has a plasma half-life of approximately 50 hours and about 99% is bound to plasma proteins. INDICATIONS • For the symptomatic relief of pain and inflammation in patients with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. • However, it should not be the first choice of non-steroidal anti-inflammatory drug (NSAID) treatment in these conditions. CONTRAINDICATIONS • Piroxicam should not be prescribed to patients who are more likely to develop side effects, such as those with history of gastrointestinal disorders associated with bleeding or those who have had skin reactions to other medicines. • Should not be used in patients sensitive to aspirin and non-steroidal anti-inflammatory drugs (NSAIDs). • Should be avoided in patients with acute porphyria. • Piroxicam should not be prescribed in association with any other NSAID or an anticoagulant. PRECAUTIONS • Should be used with caution in geriatric patients and in patients with upper gastrointestinal disease, cardiovascular disorders, hypertension, liver cirrhosis, nephrotic syndrome and impaired renal function. • Safety for use in pregnancy has not been established. • Not recommended for use in nursing mothers as clinical sa Прочетете целия документ