Страна: САЩ
Език: английски
Източник: NLM (National Library of Medicine)
PYRANTEL PAMOATE (UNII: 81BK194Z5M) (PYRANTEL - UNII:4QIH0N49E7)
Bimeda Inc.
ORAL
OTC
INDICATIONS FOR USE : For the removal and control of mature infections of large strongyles (Strongylus vulgaris, S. edentatus, S. equinus ); small strongyles; pinworms (Oxyuris equi ); and large roundworms (Parascaris equorum ) in horses and ponies. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.
Abbreviated New Animal Drug Application
EXODUS MULTI-DOSE- PYRANTEL PAMOATE PASTE BIMEDA INC. ---------- Approved by FDA under ANADA # 200-350 EXODUS® MULTI-DOSE (PYRANTEL PAMOATE) PASTE HORSE DEWORMER READ ENTIRE CARTON CAREFULLY BEFORE USING THIS PRODUCT DESCRIPTION: Exodus® Multi-Dose (pyrantel pamoate) Paste is a pale yellow to buff paste containing 43.9% w/w pyrantel pamoate in an inert vehicle. Each syringe contains 7.2 grams pyrantel base in 47.2 grams paste. Each mL contains 171 mg pyrantel base as pyrantel pamoate. COMPOSITION: Pyrantel pamoate is a compound belonging to a family classified chemically as tetrahydropyrimidines. It is a yellow, water-insoluble crystalline salt of the tetrahydropyrimidine base and pamoic acid containing 34.7% base activity. The chemical structure and name are given below. Chemical Name: (E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)-vinyl]-pyrimidine 4,4' methylenebis [3-hydroxy-2-naphtholate] (1:1) INDICATIONS FOR USE: For the removal and control of mature infections of large strongyles (_Strongylus_ _vulgaris, S. edentatus, S. equinus_); small strongyles; pinworms (_Oxyuris equi_); and large roundworms (_Parascaris equorum_) in horses and ponies. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. DOSAGE AND TREATMENT: Exodus® Multi-Dose (pyrantel pamoate) Paste is to be administered as a single oral dose of 3 mg pyrantel base per lb of body weight. The syringe has 8 weight mark increments. Each weight mark indicates the recommended dose for 300 lb of body weight. One-half syringe treats a 1200 lb horse. DOSAGE BODY WEIGHT RANGE VOLUME MG PYRANTEL BASE up to 300 lb 1/8 syringe 900 mg 301 - 600 lb 1/4 syringe 1800 mg 601 - 900 lb 3/8 syringe 2700 mg 901 - 1200lb 1/2 syringe 3600 mg NOTE: Position ring-gauge over appropriate mark on plunger. Each mL contains 171 mg pyrantel base as pyrantel pamoate. DO NOT UNDERDOSE. Ensure each animal receives a complete dose based on a current body weight. Underdosing may result in ineffective treatment, and encourage the develo Прочетете целия документ