Dyna Tetracycline Capsule 250mg

Страна: Малайзия

Език: английски

Източник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Активна съставка:

TETRACYCLINE HYDROCHLORIDE

Предлага се от:

DYNAPHARM (M) SDN BHD

INN (Международно Name):

TETRACYCLINE HYDROCHLORIDE

Броя в опаковка:

500 Capsules; 1000 Capsules

Произведено от:

DYNAPHARM (M) SDN BHD

Листовка

Consumer Medication Information Leaflet (RiMUP)
DYNA TETRACYCLINE CAPSULE
Tetracycline Hydrochloride (250 mg)
Page 1 of 2
What is in this leaflet
1.
What Dyna Tetracycline Capsule
is used for
2.
How Dyna Tetracycline Capsule
works
3.
Before you used Dyna
Tetracycline Capsule
4.
How to use Dyna Tetracycline
Capsule
5.
While you are using it
6.
Side effects
7.
Storage and disposal of Dyna
Tetracycline Capsule
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10. Date of revision
What Dyna Tetracycline Capsule is
used for
Tetracycline is an antibacterial. It is
used in the treatment infections of:
-
Respiratory tract
-
Genital-urinary tract
-
Soft tissues
-
External infections of acne
How Dyna Tetracycline Capsule
works
Tetracycline works by inhibiting
bacterial protein synthesis.
Before you use Dyna Tetracycline
Capsule
- When you must not use it
Do not use Dyna Tetracycline
Capsule in patients with known
hypersensitive to Tetracyclines and
with kidney impairment. It also
should not be used in children below
12 years as it causes tooth
discolouration.
Pregnancy and lactation
Do not take Dyna Tetracycline
Capsule if you are pregnant, trying to
get pregnant or think you may be
pregnant.
Do not take Dyna Tetracycline
Capsule if you are breast-feeding.
Ask your doctor or pharmacist for
advice before taking any medicine.
- Before you start to use it
Tell your doctor or pharmacist if you
have any of the following conditions:
- Impaired kidney function
- Liver dysfunction
- Taking other medicines
Tell your doctor if you are taking
food and milk, antacids, mineral
supplements, antacids, calcium
supplements, iron supplements,
magnesium-containing laxatives,
contraceptives, penicillins,
barbiturates and any other medicines,
including any that you buy without a
prescriptions from a pharmacy,
supermarket or health food shop.
How to use Dyna Tetracycline
Capsule
- How much to use
Adults
Antibacterial:
250-500 mg every 6 hours; or 500 mg
to 1 g every 12 hours.
Antibacterial (antiacne)
500 mg to 2 g daily in

Данни за продукта

DYNA TETRACYCLINE CAPSULE 250MG
MAL19921286AZ
DESCRIPTION:
CAPSULE
Capsule Colour
:
Yellow/Orange
Capsule Size
:
# 1
Granules Colour
:
Yellow
EACH CAPSULE CONTAINS:
Tetracycline Hydrochloride
...........................................................................................
250 mg
PHARMACODYNAMICS:
Tetracycline is a broad-spectrum bacteriostatic agent and acts by
inhibiting protein synthesis by blocking the
binding of aminoacyl tRNA ribosome complex. Reversible binding occurs
primarily at the 30S ribosomal
subunit of susceptible organisms.
PHARMACOKINETICS:
Tetracycline is incompletely and irregularly absorbed from the
gastrointestinal tract (GIT). The degree of
absorption is diminished by the soluble salts of divalent and
trivalent metals, with which tetracycline form
stable complexes and to a variable degree by milk or food. It has been
recommended that tetracycline
should be given before food. Sodium metaphosphate may enhance the
absorption of tetracycline.
As a rule, doses of 250 to 500 mg by mouth every 6 hours produce
therapeutically effective plasma
concentrations of tetracycline ranging from 1 to 3 mcg per ml and 1.5
to 5 mcg per ml respectively.
In the circulation, tetracycline is bound to plasma proteins in
varying degrees from 24 to 65 %. It is widely
distributed throughout the body tissues and fluids. Concentration of
cerebrospinal fluid (CSF) is low but may
raise of the meninges are inflamed. Tetracycline appears in the breast
milk where concentration may be
60 % or more of those in the plasma. It diffuses across the placenta
and appears in the foetal circulation in
concentrations of about 25 to 75 % of those in the maternal blood.
Only small amounts appear in saliva,
tears,
and
intra-ocular
fluids. Tetracycline
is
retained
at
sites
of
new
bone
formation
and
recent
calcification, in developing teeth, and in some injured soft tissues.
The biological half-life of tetracycline
has been reported to be about 8 to 10 hours. Tetracycline is excreted
in the urine and in the faeces. Renal
clearance i