Страна: Сингапур
Език: английски
Източник: HSA (Health Sciences Authority)
AMIODARONE HCl
SANOFI-AVENTIS SINGAPORE PTE. LTD.
C01BD01
200 mg
TABLET
AMIODARONE HCl 200 mg
ORAL
Prescription Only
SANOFI WINTHROP INDUSTRIE
ACTIVE
1998-05-27
CORDARONE AMIODARONE 200MG SCORED TABLET [SANOFI LOGO] COMPOSITION: Cordarone 200 contains 200mg of amiodarone hydrochloride. PHARMACEUTICAL FORM Tablet. Round, white tablet with a breakline on one side, imprinted with 200 and “heart-shaped” symbol on the other. CLINICAL PARTICULARS THERAPEUTIC INDICATIONS Treatment should be initiated and normally monitored only under hospital or specialist supervision. Oral Cordarone is indicated only for the treatment of severe rhythm disorders not responding to other therapies or when other treatments cannot be used. Tachyarrhythmias associated with Wolff-Parkinson-White Syndrome. Atrial flutter and fibrillation when other drugs cannot be used. All types of tachyarrhythmias of paroxysmal nature including: supraventricular, nodal and ventricular tachycardias, ventricular fibrillation: when other drugs cannot be used. POSOLOGY AND METHOD OF ADMINISTRATION _ADULTS _ It is particularly important that the minimum effective dose be used. In all cases the patient's management must be judged on the individual response and well being. The following dosage regimen is generally effective. _INITIAL STABILISATION _ Treatment should be started with 200mg, three times a day and may be continued for 1 week. The dosage should then be reduced to 200mg, twice daily for a further week. _MAINTENANCE _ The minimum effective dosage should be used according to individual response. It may range between 100mg daily to 400mg daily. Cordarone may be given on alternative days (200mg may be given every other day where 100mg are recommended daily); therapeutic windows have been also recommended (2 days a week): they are possible due to the prolonged therapeutic action of Cordarone. _GENERAL CONSIDERATIONS _ Initial dosing A high dose is needed in order to achieve adequate tissue levels rapidly. Maintenance Too high a dose during maintenance therap Прочетете целия документ
Cordarone Amiodarone 200mg Scored Tablet [sanofi logo] Composition: Cordarone 200 contains 200mg of amiodarone hydrochloride. Pharmaceutical Form Tablet. Round, white tablet with a breakline on one side, imprinted with 200 and “heart-shaped” symbol on the other. Clinical Particulars Therapeutic Indications Treatment should be initiated and normally monitored only under hospital or specialist supervision. Oral Cordarone is indicated only for the treatment of severe rhythm disorders not responding to other therapies or when other treatments cannot be used. Tachyarrhythmias associated with Wolff-Parkinson-White Syndrome. Atrial flutter and fibrillation when other drugs cannot be used. All types of tachyarrhythmias of paroxysmal nature including: supraventricular, nodal and ventricular tachycardias, ventricular fibrillation: when other drugs cannot be used. Posology and Method of Administration Adults It is particularly important that the minimum effective dose be used. In all cases the patient's management must be judged on the individual response and well being. The following dosage regimen is generally effective. Initial Stabilisation Treatment should be started with 200mg, three times a day and may be continued for 1 week. The dosage should then be reduced to 200mg, twice daily for a further week. Maintenance The minimum effective dosage should be used according to individual response. It may range between 100mg daily to 400mg daily. Cordarone may be given on alternative days (200mg may be given every other day where 100mg are recommended daily); therapeutic windows have been also recommended (2 days a week): they are possible due to the prolonged therapeutic action of Cordarone. General Considerations Initial dosing A high dose is needed in order to achieve adequate tissue levels rapidly. Maintenance Too high a dose during maintenance therapy can cause side effects which are believed to be related to high tissue levels of amiodarone and its metabolites. Amiodarone is strongly protein bound and has an average Прочетете целия документ