Cobal 500mcg tablet 500 mcg

Страна: Йордания

Език: английски

Източник: JFDA (Jordan Food & Drug Administration - المؤسسة العامة للغذاء والدواء)

Активна съставка:

Mecobalamin 500 mcg

Предлага се от:

الشركة الأردنية لإنتاج الأدوية - Jordan Pharmaceutical Manufacturer (JPM)

АТС код:

B03BA05

INN (Международно Name):

Mecobalamin 500 mcg

дозиране:

500 mcg

Броя в опаковка:

30 Tab

Произведено от:

JORDANIAN.PHARM.MANUFACTURING CO.(JPM)./JORDAN (الاردن)

Каталог на резюме:

4.44 :سعر الجمهور + الضريبة

Листовка

DESCRIPTION
COBAL is the trade name of Mecobalamin, a naturally occurring Vitamin
B12 substance,
used in the treatment of pernicious anemia and other vitamin B12
deficiency states as well as
peripheral neuropathies.
□ Each Film-Coated COBAL 500 µg Tablet contains Mecobalamin 500
µg.
□ Each COBAL 500 µg Orodispersible Tablet (ODT) contains
Mecobalamin 500 µg.
□ Each COBAL Injection contains Mecobalamin 500 µg.
EXCIPIENTS:
□ COBAL Film- Coated Tablet: lactose, maize starch, povidone K 30,
magnesium stearate,
hydroxypropyl methylcellulose type 2910, titanium dioxide,
polyethylene glycol 400, white
bees wax.
□ COBAL Orodispersible Tablet (ODT): pharmaburst C1, croscarmelose
sodium, aspartame,
povidone 30, cherry powder, magnesium stearate.
□ COBAL injection: mannitol (pyrogen free), water for injection.
CHEMISTRY
Mecobalamin is: Cobinamide, Co-methyl derivative, dihydrogen phosphate
(ester), inner salt
3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole.
CLINICAL PHARMACOLOGY
Mecobalamin is a B12 coenzyme that occurs naturally in the blood and
the cerebrospinal
fluid. Mecobalamin is necessary for various metabolic functions,
including fat and
carbohydrate metabolism and protein synthesis, and is necessary for
growth, cell replication,
hematopoiesis and nucleoprotein and myelin synthesis, largely due to
its effects on
metabolism of methionine, folic acid, and malonic acid. In effect,
Mecobalamin inhibits nerve
fiber degeneration in case of neuropathy and accelerates the repair of
nerve tissue, as
demonstrated by animal studies. Accordingly Mecobalamin is useful in
the treatment of
numbness, pain, and paralysis due to peripheral neuropathies including
diabetic neuropathy
and polyneuritis.
Mecobalamin promotes the maturation and division of erythroblast and
heme synthesis,
thereby improving the blood picture in anemia. Clinically, Mecobalamin
injection has been
shown to benefit megaloblastic anemia and peripheral neuropathies such
as diabetic
neuropathy and polyneurities. The increment in p