Страна: Йордания
Език: английски
Източник: JFDA (Jordan Food & Drug Administration - المؤسسة العامة للغذاء والدواء)
Cefpodoxime (Proxetil) 200 mg
الشركة الدولية للدواء - Pharma International Company
J01DD13
Cefpodoxime (Proxetil) 200 mg
200 mg
10
Pharma International Company/Jordan (الاردن)
13.73 :سعر الجمهور + الضريبة
Approved by: Amani AlAloul, Abdalrahim Mahmoud Ismail, Abed Al-hamdan, Eman Jaber on 14/10/2017 _REV.DATE APR 2016 I 021 04_ COMPOSITION CEFODOX ® 100MG TABLET: Each tablet contains Cefpodoxime proxetil equivalent to 100 mg Cefpodoxime. CEFODOX ® 200MG TABLET: Each tablet contains Cefpodoxime proxetil equivalent to 200 mg Cefpodoxime. CEFODOX ® 50MG DRY SUSPENSION: Each 5 ml contains Cefpodoxime proxetil equivalent to 50 mg Cefpodoxime. CEFODOX ® 100MG DRY SUSPENSION: Each 5 ml contains Cefpodoxime proxetil equivalent to 100 mg Cefpodoxime. CEFODOX ® 40MG DRY SUSPENSION: Each 5 ml contains Cefpodoxime proxetil equivalent to 40 mg Cefpodoxime. _PHARMACOLOGICAL PROPERTIES_ CEFODOX ® (Cefpodoxime proxetil) is an orally active, broad spectrum; semisynthetic third generation cephalosporin. Cefpodoxime proxetil is a prodrug that undergoes de-esterification to the active metabolite Cefpodoxime. Cefpodoxime proxetil is rapidly absorbed after oral administration reaching peak plasma conentration within 2-3 hours. It is widely distributed to most body tissues reaching a concentration higher than MIC 90 of S. pyogenes in tonsil tissues for more than 7 hours & a higher conentration than MIC 90 of Streptococcus pneumoniae & H. influenzae in lung tissues for more than 12 hours. Cefpodoxime proxetil undergoes minimal metabolism & almost 33% of the dose is excreted unchanged renally. Cefpodoxime proxetil inhibits bacterial cell wall synthesis & exerts a bactericidal activity against a wide range of gram positive & gram negative bacteria with a high stability in the presence of beta lactamase enzymes. It is usually active against the following organisms in vitro & in clinical infections: G +VE AEROBES - Streptococcus pneumoniae. - Streptococcus pyogenes. - Staphylococcus aureus (including β lactamase producing strains). - Staphylococcus saprophyticus. G -VE AEROBES - Escherichia coli. - Haemophilus influenzae (including β lactamase producing strains). - Klebsiella pneumoniae. - Moraxella (Branhamella)catarrhalis ( includi Прочетете целия документ