CARBOCAINE 1% SOLUTION

Страна: Канада

Език: английски

Източник: Health Canada

Активна съставка:

MEPIVACAINE HYDROCHLORIDE

Предлага се от:

PFIZER CANADA ULC

АТС код:

N01BB03

INN (Международно Name):

MEPIVACAINE

дозиране:

10MG

Лекарствена форма:

SOLUTION

Композиция:

MEPIVACAINE HYDROCHLORIDE 10MG

Начин на приложение:

INTRACAUDAL

Броя в опаковка:

30 ML

Вид предписание :

Ethical

Терапевтична област:

LOCAL ANESTHETICS

Каталог на резюме:

Active ingredient group (AIG) number: 0100583003; AHFS:

Статус Оторизация:

APPROVED

Дата Оторизация:

2017-08-02

Данни за продукта

1
PRESCRIBING INFORMATION
CARBOCAINE 1%
10 mg/mL, Mepivacaine Hydrochloride Injection, USP
CARBOCAINE 2%
20 mg/mL, Mepivacaine Hydrochloride Injection, USP
Local Anesthetic
Pfizer Canada Inc.
17300 Trans-Canada Highway
Kirkland, Québec
H9J 2M5
DATE OF REVISION:
August 2, 2017
Control Number: 204807
2
PRESCRIBING INFORMATION
CARBOCAINE 1%
10 mg/mL, Mepivacaine Hydrochloride Injection, USP
CARBOCAINE 2%
20 mg/mL, Mepivacaine Hydrochloride Injection, USP
Local Anesthetic
PHARMACOLOGY: Mepivacaine stabilizes the neuronal membrane and
prevents the initiation and
transmission of nerve impulses, thereby effecting local anesthesia.
Its pharmacological properties
are somewhat similar to those of lidocaine, which it resembles
chemically. Its action is more rapid
in onset and somewhat more prolonged than that of lidocaine. It has
been employed for all types of
infiltration and regional nerve block anesthesia.
Onset of anesthesia is rapid, the time of onset for sensory block
ranging from about 3 to 20
minutes depending upon such factors as the anesthetic technique, the
type of block, the
concentration of the solution and the individual patient. The degree
of motor blockade produced is
dependent on the concentration of the solution. The 1% concentration
will block sensory and
sympathetic conduction without loss of motor function and will be
effective in small superficial
nerve blocks. The 2% concentration of mepivacaine will produce
complete sensory and motor
block of any nerve group.
The duration of anesthesia also varies depending upon the technique
and type of block, the
concentration and the individual. Mepivacaine will normally provide
anesthesia which is
adequate for 2 to 2½ hours of surgery. It has been reported that
vasoconstrictors do not
significantly prolong anesthesia with mepivacaine, but epinephrine
(1:200 000) may be added to
the mepivacaine solution to promote local hemostasis and to delay
systemic absorption of the
anesthetic.
The
drowsiness
and
lassitude
seen
with
lidocaine
have
not
been
commonly
noted
wit