Abecab 5/20 Tablet

Страна: Бангладеш

Език: английски

Източник: DGDA (Directorate General of Drug Administration)

Активна съставка:

Amlodipine + Olmesartan Medoxomil

Предлага се от:

Advanced Chemical Industries Limited

INN (Международно Name):

Amlodipine + Olmesartan Medoxomil

дозиране:

5 mg + 20 mg

Лекарствена форма:

Tablet

Данни за продукта

Only for the use of Medical Professionals
ABECAB
®
Amlodipine Besylate & Olmesartan Medoxomil
DESCRIPTION
Abecab
®
is
a
combination
preparation
of
Amlodipine
Besylate
&
Olmesartan
Medoxomil.Amlodipine is a calcium channel blocker that acts directly
on vascular
smooth muscle to cause a reduction in peripheral vascular resistance
and reduction
in blood pressure. Olmesartan blocks the vasoconstrictor effects of
Angiotensin II by
selectively blocking the binding of Angiotensin II to the AT
1
receptor in vascular
smooth muscle. Its action is, therefore, independent of the pathways
for Angiotensin
II synthesis.
INDICATIONS
Abecab
®
is
indicated
for
the
treatment
of
hypertension,
alone
or
with
other
antihypertensive agents.
Abecab
®
may also be used as initial therapy in patients who are likely to need
multiple antihypertensive agents to achieve their blood pressure
goals.
DOSAGE AND ADMINISTRATION
_GENERAL CONSIDERATIONS _
Maximum antihypertensive effects are attained within 2 weeks. Abecab
®
may be
taken
with
or
without
food.
Abecab
®
may
be
administered
with
other
antihypertensive agents. Dosage may be increased after 2 weeks. The
maximum
recommended dose of Abecab
®
is 2 tablets (10/40 mg) once daily.
_INITIAL THERAPY _
The usual starting dose of Abecab
®
is one tablet (5/20 mg) once daily. Depending on
the blood pressure response, the dose may be titrated at intervals of
1-2 weeks to
two tablets of Abecab
®
(10/40 mg) once daily.
_REPLACEMENT THERAPY _
Abecab
®
may
be
substituted
for
its
individually
titrated
components.
When
substituting for individual components, the dose of one or both of the
components
can be increased if blood pressure control has not been satisfactory.
_ _
_ADD-ON THERAPY _
Abecab
®
may be used to provide additional blood pressure lowering for patients
not
adequately controlled with Amlodipine (or another dihydropyridine
calcium channel
blocker) alone or with Olmesartan Medoxomil (or another Angiotensin
receptor
blocker) alone.
_ _
ELDERLY PATIENTS
No dosage adjustment is necessary