البلد: ماليزيا
اللغة: الإنجليزية
المصدر: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
QUETIAPINE FUMARATE
UNIMED SDN BHD
QUETIAPINE FUMARATE
10X10tablet Tablets
Hetero Labs Limited
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ QUTERO TABLETS Quetiapine (100mg, 200mg, 300mg) 1 WHAT IS IN THIS LEAFLET? 1. What QUTERO Tablets is used for 2. How QUTERO works 3. Before you take QUTERO 4. How to use QUTERO 5. While you are using it 6. Side effects 7. Storage and Disposal of QUTERO 8. Product description 9. Manufacturer 10. Product Registration Holder 11. Date of revision WHAT QUTERO IS USED FOR QUTERO can be used to treat several illnesses, such as: • Schizophrenia: where you may hear or feel things that are not there, believe things that are not true or feel unusually suspicious, anxious, confused, guilty, tense or depressed. • Acute Mania episode: where you may feel very excited, elated, agitated, enthusiastic or hyperactive or have poor judgment including being aggressive or disruptive. • Associated with bipolar disorder: (extreme mood swings ranging from episodes of depression to mania) where you may feel sad all the time or you may find that you feel depressed, feel guilty, lack energy, lose your appetite or can’t sleep. Your doctor may continue to prescribe QUTERO even when you are feeling better. HOW QUTERO WORKS QUTERO contains a substance called quetiapine. It belongs to a group of medicines called anti-psychotics. Illnesses that affects the brain, such as psychotic disorders may cause by lack of certain chemicals in the brain. QUTERO helps to put right this imbalance of chemicals in certain parts of the brain- mainly dopamine and serotonin. BEFORE YOU USE QUTERO _When you must not use it _ Do not take QUTERO if: • you are allergic (hypersensitive) to quetiapine or any of the other ingredients of QUTERO • QUTERO contains lactose monohydrate which is a type of sugar. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine. • If you are taking any of the following medicines: Some medicines for human immunodeficiency virus (HIV); azole medicines (for fungal infections); medicines for an infection (li اقرأ الوثيقة كاملة
QUTERO 100 / 200 / 300 (QUETIAPINE TABLETS 100MG/ 200MG/ 300MG) DESCRIPTION AND COMPOSITION: QUTERO 100 (Quetiapine Tablets 100mg): _Description:_ Yellow colored, round shaped, biconvex, film-coated tablets debossed with ‘55’ on one side and ‘I’ on other side. _Composition:_ Each film-coated tablet contains Quetiapine Fumarate equivalent to 100 mg of Quetiapine. QUTERO 200 (Quetiapine Tablets 200mg): _Description:_ White to off white colored, round shaped, biconvex, film-coated tablets debossed with ‘56’ on one side and ‘I’ on other side. _Composition:_ Each film-coated tablet contains Quetiapine Fumarate equivalent to 200 mg of Quetiapine. QUTERO 300 (Quetiapine Tablets 300mg): _Description:_ White to off white colored, capsule shaped, biconvex, film-coated tablets debossed with ’45’ on one side and ‘I’ on other side. _Composition:_ Each film-coated tablet contains Quetiapine Fumarate equivalent to 300 mg of Quetiapine. PHARMACODYNAMICS _MECHANISM OF ACTION _ Quetiapine is an atypical antipsychotic agent. Quetiapine and the active human plasma metabolite, norquetiapine interact with a broad range of neurotransmitter receptors. Quetiapine and norquetiapine exhibit affinity for brain serotonin (5HT 2 ) and dopamine D 1 - and D 2 - receptors. It is this combination of receptor antagonism with a higher selectivity for 5HT 2 relative to D 2 - receptors, which is believed to contribute to the clinical antipsychotic properties and low extrapyramidal side effect (EPS) liability of quetiapine. Additionally, norquetiapine has high affinity for the norepinephrine transporter (NET). Quetiapine and norquetiapine also have high affinity at histaminergic and adrenergic α 1 receptors, with a lower affinity at adrenergic α 2 and serotonin 5HT 1 A receptors. Quetiapine has no appreciable affinity at cholinergic muscarinic or benzodiazepine receptors. _PHARMACODYNAMIC EFFECTS _ Quetiapine is active in tests for antipsychotic activity, such as conditioned avoidance. It also blocks the action of dopamine ag اقرأ الوثيقة كاملة