البلد: الولايات المتحدة
اللغة: الإنجليزية
المصدر: NLM (National Library of Medicine)
MUPIROCIN (UNII: D0GX863OA5) (MUPIROCIN - UNII:D0GX863OA5)
Oaklock, LLC
TOPICAL
PRESCRIPTION DRUG
Mupirocin Ointment USP, 2% is indicated for the topical treatment of impetigo due to: S. aureus and S. pyogenes . This drug is contraindicated in patients with known hypersensitivity to any of the constituents of the product. Antiseptic - surgical hand scrub: significantly reduces the number of microorganisms on the hands and forearms prior to surgery or patient care - healhcare personnel handwash: helps reduce bacteria that potentially can cause disease - patient preoperative skin preparation: for the preparation of the patient's skin prior to surgery - skin wound and general skin cleansing - if you or the patient is allergic to chlorhexidine gluconate or any other ingredient in this product - in contact with meninges - in the genital area - as a preoperative skin preparation of the head or face irritation, sensitization, or allergic reaction occurs. These may be signs of a serious condition. Antiseptic - First aid antiseptic to help prevent infection in minor cuts, scrapes
Mupirocin Ointment USP, 2% is available as follows: 22 g tube (NDC 45802- 112 -22) Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature]. *Bactroban Nasal® is a registered trademark of GlaxoSmithKline.
unapproved drug other
PS2 ACIURGY PACK- MUPIROCIN 2%, CHLORHEXIDINE GLUCONATE 4%, POVIDONE- IODINE OAKLOCK, LLC _Disclaimer: This drug has not been found by FDA to be safe and effective, and this_ _labeling has not been approved by FDA. For further information about unapproved_ _drugs, click here._ ---------- PS2 ACIURGY PACK For Dermatologic Use RX ONLY -------------------- Mupirocin Ointment USP, 2% -------------------- DESCRIPTION Each gram of Mupirocin Ointment USP, 2% contains 20 mg mupirocin in a bland water miscible ointment base (polyethylene glycol ointment, NF) consisting of polyethylene glycol 400 and polyethylene glycol 3350. Mupirocin is a naturally occurring antibiotic. The chemical name is ( _E_)-(2 _S_,3 _R_,4 _R_,5 _S_)-5-[(2 _S_,3 _S_,4 _S_,5 _S_)-2,3-Epoxy-5-hydroxy-4- methylhexyl]tetrahydro-3,4-dihydroxy-β-methyl-2 _H_-pyran-2-crotonic acid, ester with 9- hydroxynonanoic acid. The molecular formula of mupirocin is C H O and the molecular weight is 500.62. The chemical structure is: CLINICAL PHARMACOLOGY Application of C-labeled mupirocin ointment to the lower arm of normal male subjects followed by occlusion for 24 hours showed no measurable systemic absorption (<1.1 nanogram mupirocin per milliliter of whole blood). Measurable radioactivity was present in the stratum corneum of these subjects 72 hours after application. Following intravenous or oral administration, mupirocin is rapidly metabolized. The principal metabolite, monic acid, is eliminated by renal excretion, and demonstrates no antibacterial activity. In a trial conducted in 7 healthy adult male subjects, the elimination half-life after intravenous administration of mupirocin was 20 to 40 minutes for mupirocin and 30 to 80 minutes for monic acid. The pharmacokinetics of mupirocin has not been studied in individuals with renal insufficiency. 26 44 9 14 not been studied in individuals with renal insufficiency. MICROBIOLOGY - Mupirocin is an antibacterial agent produced by fermentation using the organism _Pseudomonas fluorescens_. Mupirocin inhibits bacte اقرأ الوثيقة كاملة