POTRELEASE TR TABLET 600MG

البلد: ماليزيا

اللغة: الإنجليزية

المصدر: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

العنصر النشط:

POTASSIUM CHLORIDE

متاح من:

SM PHARMACEUTICALS SDN. BHD.

INN (الاسم الدولي):

POTASSIUM CHLORIDE

الوحدات في الحزمة:

1x10 Tablets; 100x10 Tablets; 10x10 Tablets

المصنعة من قبل:

SM PHARMACEUTICALS SDN. BHD.

نشرة المعلومات

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
POTRELEASE TR TABLET
Potassium chloride (600mg)
____________________________________________________________________________________________________________________________
_________________________________________________________________________________________________________
1
WHAT IN THIS LEAFLET
1.What Potrelease TR Tablet is used for
2.How Potrelease TR Tablet works
3.Before you use Potrelease TR Tablet
4.How to take Potrelease TR Tablet
5.While you are using it
6.Side Effects
7.Storage and Disposal of Potrelease TR
Tablet
8.Products Descriptions
9.Manufacturer and Product Registration
Holder
10.Date of revision WHAT POTRELEASE TR TABLET IS USED FOR
For treatment and prevention of
low level of potassium in blood.
HOW POTRELEASE TR TABLET WORKS
This medication is used to replenish
potassium in blood.
BEFORE YOU USE POTRELEASE TR TABLET
_-When you must not use it _
Do not use Potrelease TR tablet if you
are/have:_ _
•
Severe kidney impairment (you
may produce little or no urine).
•
Untreated (Addison's disease
(inadequate production of
hormones by adrenal glands)
•
Dehydrated
•
Heat cramps
•
High level of potassium in blood
•
Intestinal obstruction, abnormal
movement or ulceration
•
Too much acid
in the body
_-Before you start to use it _
Please consult your doctor or pharmacist if
you are pregnant, planning for pregnancy or
breast-feeding before using any medicine
_-Taking other medicine _
Talk to your doctor/pharmacist if you are
taking any medicine including those you
buy without a prescription from a
pharmacy, supermarket or health food shop.
Medications that may interfere with
Potrelease TR tablet are:
•
Medication for high blood pressure:
Captopril
•
Slow heart rate and insecticide
poisoning medication: Atropine
•
Calcium salts
•
Heart medication: Digitalis glycoside
•
Hormone therapy: Adrenocorticoids,
Glucocorticoids, Corticotrophin
(ACTH)
•
Medication for high blood potassium
level: sodium polystyrene sulfonate
•
Laxatives

خصائص المنتج

Package Insert
Page 1 of 5
SM PHARMACEUTICALS SDN. BHD.
POTRELEASE TR TABLET
(POTASSIUM CHLORIDE 600 MG)
DESCRIPTION:
Round shaped with deep concave surface film coated tablet
Colour: Yellow
COMPOSITION:
Each tablet contains potassium chloride BP 600 mg
ACTIONS AND MODE OR MECHANISMS OF ACTION:
Potassium is the predominant cation (150 mEq per liter) within cells.
Intracellular
sodium content is relatively low. In extracellular fluid, sodium
predominates and the
potassium content is low (4 to 5 mEq per liter). A membrane- bound
enzyme, sodium-
potassium-activated adenosine triphosphatase (Na+ K+ ATPase), actively
transports or
pumps sodium out of and potassium into cells in order to maintain
these concentration
gradients. The gradients are necessary for the conduction of nerve
impulses in such
specialized tissues as the heart, brain, and skeletal muscle, and to
maintain normal renal
function
and
acid-base
balance.
High
intracellular
potassium
concentrations
are
necessary for numerous cellular metabolic processes.
PHARMACOLOGY
(SUMMARY
OF
PHARMACODYNAMICS
AND
PHARMACOKINETICS):
Pharmacokinetics:
Onset
and
Duration:
Peak
elevation
of
serum
potassium
levels
following SR preparations is highly delayed (2hours) compared to
liquid form (1 hour).
Effect on serum potassium is generally confined to the first 3 hours
after dosing.
Plasma Levels: (May vary depending on laboratory) 3.5 – 5 mEq/L
(adult and child); 5 –
7.5 mEq/L (newborn); total body stores are approximately 50 mEq/kg or
3500 mEq. As
a general rule, a decrease of 1 mEq/L in serum potassium reflects a 10
– 20 % total body
deficit; however, there is considerable variation; signs of
hypokaleamia appear below
2.5 mEq/L; Levels above 7 mEq/L are dangerous. Clinical signs of
hyperkaleamia are
not reliable indicators of serum levels. Alkalosis decreases levels
and acidosis increases
levels.
Fate: When initially administered the rates of absorption and
excretion are more rapid
with
the
liquid
than
the
SR
forms;
however,
bioavailability
is
the
same
when
administe