البلد: إسرائيل
اللغة: الإنجليزية
المصدر: Ministry of Health
ISOFLURANE
PHARMA MEDIS
N01AB06
LIQUID FOR INHALATION
ISOFLURANE 100 %V/V
INHALATION
Required
PIRAMAL CRITICAL CARE INC., USA
ISOFLURANE
ISOFLURANE
General inhalation anesthetic.
2022-04-30
.תשפיחש המ תא ונאצמ אל הנוכנ תנזהש תבותכה םא קודבל יאדכ תבותכב עייסל חמשנ info@gov.il ( 1 ) اقرأ الوثيقة كاملة
1 / 12 PHYSICIAN'S PRESCRIBING INFORMATION 1. NAME OF THE MEDICINAL PRODUCT Isoflurane USP, Terrell TM 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Isoflurane 100% Each 100 ml bottle Isoflurane contains 100 ml isoflurane. Each 250 ml bottle Isoflurane contains 250 ml isoflurane. 3. PHARMACEUTICAL FORM Liquid for inhalation 4. CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS For general inhalation anaesthesia. 4.2 POSOLOGY AND METHOD OF ADMINISTRATION In order to be able to accurately control the precise concentration of isoflurane, vaporisers that have been specially calibrated for isoflurane should be used. INDUCTION OF ANAESTHESIA: If isoflurane is used for induction of anaesthesia, a starting concentration of 0.5% is recommended. Concentrations of 1.3-3.0% usually bring about surgical anaesthesia within 7 to 10 minutes. It is recommended that use be made of a hypnotic dose of a short acting barbiturate or another product such as propofol, etomidate, or midazolam in order to avoid coughing or laryngospasm, which can arise if induction is carried out with Isoflurane alone or in combination with oxygen or with an oxygen-nitrous oxide mixture. MAINTENANCE OF ANAESTHESIA: Anaesthesia can be maintained during surgery using a concentration of 1.0-2.5% with the simultaneous administration of N 2 O and O 2 . A higher concentration of 1.5-3.5% of Isoflurane is necessary if Isoflurane is administered with pure oxygen. RECOVERY: The concentration of Isoflurane must be reduced to 0.5% at the end of the operation, or to 0% during closure of the wound to allow prompt recovery. If all administration of anaesthetic agents has been stopped, the air passages of the patient should be ventilated several times with 100% oxygen until complete awakening occurs. 2 / 12 If the vector gas is a mixture of 50% O 2 and 50% N 2 O, the value of the minimum alveolar concentration of isoflurane is approximately 0.65%. ADULTS AGE AVERAGE MAC VALUE IN 100% OXYGEN 70% N2O 26 ± 4 years 1.28% 0.56% 44 ± 7 years 1.15% 0.50% 64 ± 5 years 1.05% 0.37 اقرأ الوثيقة كاملة