البلد: الولايات المتحدة
اللغة: الإنجليزية
المصدر: NLM (National Library of Medicine)
GENTAMICIN SULFATE (UNII: 8X7386QRLV) (GENTAMICIN - UNII:T6Z9V48IKG)
Padagis Israel Pharmaceuticals Ltd
GENTAMICIN SULFATE
GENTAMICIN 1 mg in 1 g
TOPICAL
PRESCRIPTION DRUG
Primary skin infections: Impetigo contagiosa, superficial folliculitis, ecthyma, furunculosis, sycosis barbae, and pyoderma gangrenosum. Secondary skin infections: Infectious eczematoid dermatitis, pustular acne, pustular psoriasis, infected seborrheic dermatitis, infected contact dermatitis (including poison ivy), infected excoriations, and bacterial superinfections of fungal or viral infections. Please Note: Gentamicin Sulfate is a bactericidal agent that is not effective against viruses or fungi in skin infections. It is useful in the treatment of infected skin cysts and certain other skin abscesses when preceded by incision and drainage to permit adequate contact between the antibiotic and the infecting bacteria. Good results have been obtained in the treatment of infected stasis and other skin ulcers, infected superficial burns, paronychia, infected insect bites and stings, infected lacerations and abrasions, and wounds from minor surgery. Patients sensitive to neomycin can be treated with Gentamicin Sul
Gentamicin Sulfate Cream USP, 0.1% is available as follows: 15 g tube (NDC 45802-056 -35) 30 g tube (NDC 45802-056 -11)
Abbreviated New Drug Application
GENTAMICIN SULFATE- GENTAMICIN SULFATE CREAM PADAGIS ISRAEL PHARMACEUTICALS LTD ---------- GENTAMICIN SULFATE CREAM USP, 0.1% _FOR DERMATOLOGIC USE ONLY_ _NOT FOR OPHTHALMIC USE_ _RX ONLY_ DESCRIPTION Gentamicin Sulfate Cream USP, 0.1% is a wide spectrum antibiotic preparation for topical administration. Each gram of Gentamicin Sulfate Cream USP, 0.1% contains Gentamicin Sulfate USP equivalent to 1 mg of gentamicin base in a cream base of isopropyl myristate, propylene glycol, propylene glycol monostearate, polysorbate 40, purified water, sorbitol solution, and stearic acid, with methylparaben and butylparaben as preservatives. CLINICAL PHARMACOLOGY Gentamicin Sulfate is a wide spectrum antibiotic that provides highly effective topical treatment in primary and secondary bacterial infections of the skin. Gentamicin Sulfate Cream USP, 0.1% may clear infections that have not responded to other topical antibiotic agents. In primary skin infections such as impetigo contagiosa, treatment three or four times daily with Gentamicin Sulfate Cream USP, 0.1% usually clears the lesions promptly. In secondary skin infections, Gentamicin Sulfate Cream USP, 0.1% aids in the treatment of the underlying dermatosis by controlling the infection. Bacteria susceptible to the action of gentamicin sulfate include sensitive strains of _Streptococci_ (group A beta-hemolytic, alpha-hemolytic), _Staphylococcus aureus_ (coagulase positive, coagulase negative, and some penicillinase-producing strains), and the gram-negative bacteria, _Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus_ _vulgaris and Klebsiella pneumoniae_. INDICATIONS AND USAGE Primary skin infections: Impetigo contagiosa, superficial folliculitis, ecthyma, furunculosis, sycosis barbae, and pyoderma gangrenosum. Secondary skin infections: Infectious eczematoid dermatitis, pustular acne, pustular psoriasis, infected seborrheic dermatitis, infected contact dermatitis (including poison ivy), infected excoriations, and bacterial superinfections of fungal or v اقرأ الوثيقة كاملة