DYNAVATE CREAM 0.1%

البلد: ماليزيا

اللغة: الإنجليزية

المصدر: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

العنصر النشط:

BETAMETHASONE VALERATE

متاح من:

DYNAPHARM (M) SDN BHD

INN (الاسم الدولي):

BETAMETHASONE VALERATE

الوحدات في الحزمة:

15 gm

المصنعة من قبل:

DYNAPHARM (M) SDN BHD

نشرة المعلومات

DYNAVATE CREAM
Betamethasone Valerate (0.1% w/w)
1
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
WHAT IS IN THIS LEAFLET
1.
What DYNAVATE CREAM is used
for
2.
How DYNAVATE CREAM works
3.
Before you use DYNAVATE
CREAM
4.
How to use DYNAVATE CREAM
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of
DYNAVATE CREAM
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10.
Date of revision
WHAT DYNAVATE CREAM IS USED
FOR
For the relief of skin inflammation that is
responsive to corticosteroid.
HOW DYNAVATE CREAM WORKS
It is responsible for anti-inflammatory
effects to topical application of
corticosteroid.
BEFORE YOU USE DYNAVATE CREAM
-
_When you must not use it _
Do not use it if you have:
-
Facial redness
-
Acne
-
Small bumps around the mouth
-
Viral infections
-
Bacterial and fungal infections
-
Hypersensitivity to Betamethasone or
the preparation.
-
Diabetes
-
Increased pressure in the eye
_Pregnancy and lactation _
_ _
Do not use DYNAVATE CREAM if you
are pregnant, trying to get pregnant or
think you may be pregnant.
Do not use DYNAVATE CREAM if you
are breast-feeding. Ask your doctor or
pharmacist for advice before taking any
medicine.
-
_Before you start use it _
Topical applications of corticosteroid
should not be made with an occlusive
dressing to large areas of the body
because of the increased risk of systemic
toxicity. Corticosteroid should not be
applied to ulcers of the leg.
-
_Taking other medicines _
Tell your doctor if you are taking any
other medicines, including any that you
buy without a prescription from a
pharmacy, supermarket or health food
shop.
HOW TO USE DYNAVATE CREAM
-
_How much to use _
Apply thinly to the affected parts.
Follow all directions given to you by
your doctor and pharmacist carefully.
They may differ from the information
contained in this leaflet. If you do not
understand the instructions on the label,
ask your doctor or pharmacist for help.
-
_When to use it _
Use two to three times daily or as
directed by your doctor or pharmacist.
-
_Ho

خصائص المنتج

DYNAVATE CREAM
MAL19950042AZ
DESCRIPTION:
CREAM
Colour
:
White
Fragrance
:
Baby Jo
CONTENT:
Betamethasone 17-Valerate equivalent to Betamethasone
................... 0.1% w/w
(Fragrance: Baby Jo, Preservative: Chlorocresol 0.1%)
PHARMACODYNAMICS:
Corticosteroids diffuse across cell membranes and complex with
specific cytoplasmic receptors. These complexes
then enter the cell nucleus, bind to DNA and stimulate transcription
of messenger RNA (mRNA) and subsequent
protein synthesis of various enzymes thought to be ultimately
responsible for anti-inflammatory effects to topical
application of corticosteroid.
PHARMACOKINETICS:
Corticosteroids when administered by topical application, particularly
under an occlusive dressing or when the skin is
broken, sufficient corticosteroid may be absorbed to give systemic
effects. Corticosteroids in the circulation are
extensively bound to plasma proteins, mainly to globulin and less so
to albumin. The corticosteroid-binding globulin
has high affinity but low binding capacity, which the albumin has low
affinity but large binding capacity. Only
unbound corticosteroid has
pharmacological effects or
is metabolised. The synthetic corticosteroids are less
extensively protein bound than hydrocortisone (cortisol). They also
tend to have longer half-lives. Corticosteroids are
metabolised mainly in the liver but also in the kidney, and are
excreted in the urine. The slower metabolism of the
synthetic corticosteroids with their lower protein-binding affinity
may account for their increased potency compared
with the natural corticosteroids.
INDICATION:
For the relief of inflammatory manifestations of
corticosteroid-responsive dermatoses.
RECOMMENDED DOSE:
Apply thinly to the affected parts two to three times daily.
CONTRAINDICATION:
Rosacea, acne vulgaris, perioral dermatitis, viral infections,
bacteria and fungal infections and hypersensitivity to the
preparation. It is also contraindicated in patients with diabetes
mellitus, tuberculosis and glaucoma.
WARNING AND PRECAUTIONS:
Topical appli