البلد: ماليزيا
اللغة: الإنجليزية
المصدر: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
CANDESARTAN CILEXETIL
CELLTRION HEALTHCARE MALAYSIA SDN. BHD.
CANDESARTAN CILEXETIL
28 Tablets
Delpharm Novara S.r.l
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ _ _ BLOPRESS ® TABLET _ _ Candesartan Cilexetil (8mg and 16mg) Page 1 WHAT IS IN THIS LEAFLET 1. What Blopress is used for 2. How Blopress works 3. Before you use Blopress 4. How to use Blopress 5. While you are using it 6. Side Effects 7. Storage and Disposal of Blopress 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT BLOPRESS IS USED FOR Blopress is used to treat high blood pressure. HOW BLOPRESS WORKS This belongs to a group of medicines called angiotensin II receptor antagonists. It works by making your blood vessels relax and widen. This helps to lower your blood pressure. It also makes it easier for your heart to pump blood to all parts of your body . BEFORE YOU USE BLOPRESS _- When you must not use it _ • If you are pregnant • If you are allergic to any component of Blopress • you are treated with a blood pressure lowering medicine containing aliskiren. _- Before you start to use it _ Before you take Blopress, tell your doctor if you: • you are pregnant or planning to get pregnant • you have kidney problem • you have liver problem _ _ _- Taking other medicines _ Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines. Blopress can affect the way some other medicines work and some medicines can have an effect on Blopress. If you are using certain medicines, your doctor may need to do blood tests from time to time. In particular, tell your doctor if you are using any of the following medicines: • Other medicines to help lower your blood pressure • Non-steroidal anti-inflammatory drugs (NSAIDs) (medicines to relieve pain and inflammation). • Potassium supplements or salt substitutes containing potassium (medicines that increase the amount of potassium in your blood). • Lithium (a medicine for mental health problems). HOW TO USE BLOPRESS _- How much to use _ • Starting dose of 4mg once daily. The dosage should be increased according to response u اقرأ الوثيقة كاملة
BLOPRESS ® TABLETS COMPOSITION _BLOPRESS_ ® Tablet 8 mg is pale pink tablet with score line on both sides, each tablet contains 8mg candesartan cilexetil. _BLOPRESS_ ® Tablet 16 mg is light pink tablet with one convex side and one scored flat side, embossing 16 candesartan cilexetil. INDICATION Treatment of Hypertension DOSAGE AND METHOD OF ADMINISTRATION A suggested starting dose of _BLOPRESS_ ® is 4 mg once daily. The dosage should be increased according to the therapeutic response until 16 mg once daily. The maximum antihypertensive effect is attained within 4 weeks of initiation treatment. ADMINISTRATION _BLOPRESS_ ® is to be taken once daily with or without food. USE IN THE ELDERLY No dosage adjustment is necessary in patients up to 75 years old. In the patients with more than 75 years, an initial dose of 2 mg is recommended. The dose may be adjusted according to response. USE IN IMPAIRED RENAL FUNCTION No dosage adjustment is necessary in patients with mild renal impairment. In the patients with moderate to severe renal impairment, an initial dose of 2 mg once daily is recommended. The dose may be adjusted according to response. USE IN IMPAIRED HEPATIC FUNCTION An initial dose of 2 mg once daily is recommended in patients with mild to moderate hepatic impairment. The dose may be adjusted according to response. There is no experience in patients with severe hepatic impairment. _BLOPRESS_ ® may be administered with other antihypertensive agents. USE IN CHILDREN The safety and efficacy of _BLOPRESS_ ® have not been established in children. CONTRAINDICATIONS - Hypersensitivity to any component of _BLOPRESS_ ® Tablets. - Pregnancy and lactation - The use of canderstan cilexetil in combination with aliskiren-containing medicines in patients with diabetes or moderate to severe renal impairment (GFR<60ml/min/1.73m 2 ) BLOPRESS ® TABLETS OVERDOSE Symptoms Although there is no experience of overdosage with _BLOPRESS_ ® based on pharmacological considerations, the main manifestation of an overdose is likely اقرأ الوثيقة كاملة