Arrow - Citalopram

البلد: نيوزيلاندا

اللغة: الإنجليزية

المصدر: Medsafe (Medicines Safety Authority)

العنصر النشط:

Citalopram hydrobromide 24.99mg equivalent to Citalopram 20 mg (anhydrous);  ;  ; Citalopram hydrobromide 24.99mg equivalent to Citalopram 20 mg (anhydrous)

متاح من:

Teva Pharma (New Zealand) Limited

INN (الاسم الدولي):

Citalopram hydrobromide 24.99 mg (equivalent to Citalopram 20 mg (anhydrous))

جرعة:

20 mg

الشكل الصيدلاني:

Film coated tablet

تركيب:

Active: Citalopram hydrobromide 24.99mg equivalent to Citalopram 20 mg (anhydrous)     Excipient: Colloidal silicon dioxide Hypromellose Macrogol 6000 Magnesium stearate Mannitol Microcrystalline cellulose Titanium dioxide Active: Citalopram hydrobromide 24.99mg equivalent to Citalopram 20 mg (anhydrous) Excipient: Colloidal silicon dioxide Magnesium stearate Mannitol Microcrystalline cellulose Opadry white 03F28539

الوحدات في الحزمة:

Blister pack, Al/PVC/PVDC, 28 tablets

الفئة:

Prescription

نوع الوصفة الطبية :

Prescription

المصنعة من قبل:

Hetero Drugs Limited

الخصائص العلاجية:

Treatment of depressive illness in the initial phase and as maintenance against potential relapse or recurrence.

ملخص المنتج:

Package - Contents - Shelf Life: Blister pack, Al/PVC/PVDC - 28 tablets - 4 years from date of manufacture stored at or below 25°C - Blister pack, Al/PVC/PVDC - 84 tablets - 4 years from date of manufacture stored at or below 25°C

تاريخ الترخيص:

2003-01-06

نشرة المعلومات

ARROW - CITALOPRAM
CITALOPRAM (AS HYDROBROMIDE) 20MG TABLETS
WHAT IS IN THIS LEAFLET
This leaflet answers some common questions about ARROW - CITALOPRAM.
It does not contain all of the available information. It does not take
the place of talking to your
doctor or pharmacist.
All medicines have benefits and risks. Your doctor has weighed the
risks of you taking
ARROW - CITALOPRAM against the benefits they expect it will have for
you.
IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, TALK TO YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH YOUR MEDICINE. You may need to read it again.
WHAT ARROW – CITALOPRAM IS USED FOR
ARROW - CITALOPRAM is used to treat depression and helps prevent
potential recurrence
of the symptoms of depression.
It belongs to a group of medicines called selective serotonin reuptake
inhibitors (SSRIs).
SSRIs are thought to work by their actions on brain chemicals called
amines, which are
involved in controlling mood.
Depression is longer lasting or more severe than the "low moods"
everyone has from time to
time due to the stress of everyday life. It is thought to be caused by
chemical imbalance in
some parts of the brain. This imbalance affects your whole body and
can cause emotional
and physical symptoms, such as feeling low in spirit, loss of interest
in activities, being unable
to enjoy life, poor appetite or over-eating, disturbed sleep, often
waking up early, loss of sex
drive, lack of energy and feeling guilty over nothing.
ARROW - CITALOPRAM corrects this chemical imbalance and may help
relieve the
symptoms of depression.
Your doctor may have prescribed ARROW - CITALOPRAM for another reason.
ASK YOUR
DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY ARROW - CITALOPRAM HAS BEEN
PRESCRIBED FOR YOU.
ARROW - CITALOPRAM is not recommended for use in children and
adolescents under 18
years of age, as safety and efficacy have not been established in this
population.
ARROW - CITALOPRAM can be given to elderly patients with a reduced
dose. The effects of
ARROW - CITALOPRAM in elderly patients are

خصائص المنتج

NEW ZEALAND DATA SHEET
ARROW - CITALOPRAM
Citalopram hydrobromide tablets
PRESENTATION
Arrow - Citalopram 20 mg Tablets: round, white, film-coated tablet,
marked with
"CT20" on one side and a break line on the other side, containing 20
mg citalopram.
Each tablet contains 24.99 mg citalopram hydrobromide corresponding to
20 mg of
citalopram base.
USES
_ACTIONS _
Biochemical and behavioural studies have shown that citalopram is a
potent inhibitor
of the serotonin (5-HT) uptake. Tolerance to the inhibition of 5-HT
uptake is not
induced by long-term treatment with citalopram.
Citalopram is the most selective serotonin reuptake inhibitor (SSRI)
yet described,
with no, or minimal, effect on noradrenaline (NA), dopamine (DA) and
gamma
aminobutyric acid (GABA) uptake. In contrast to many tricyclic
antidepressants and
some of the newer SSRIs, citalopram has no or very low affinity for a
series of
receptors
including
5-HT
1A
,
5-HT
2
,
DA
D
1
and
D
2
receptors,
α
1
-
and
α
2
-
adrenoceptors,
β-adrenoceptors,
histamine
H
1
,
muscarinic,
benzodiazepine
and
opioid receptors. A series of functional _in vitro _tests in isolated
organs as well as
functional _in vivo_ tests have confirmed the lack of receptor
affinity. This absence of
effects on receptors could explain why citalopram produces fewer of
the traditional
side
effects
of
tricyclic
antidepressants
such
as
dry
mouth,
bladder
and
gut
disturbance, blurred vision, sedation, cardiotoxicity and orthostatic
hypotension.
Suppression of rapid eye movement (REM) sleep is considered a
predictor of
antidepressant
activity.
Like
tricyclic
antidepressants,
other
SSRIs
and
MAO
inhibitors, citalopram suppresses REM-sleep and increases deep
slow-wave sleep.
The main metabolites of citalopram are all SSRIs, although their
potency and
selectivity ratios are lower than those of citalopram but higher than
those of many of
the newer SSRIs. The metabolites do not contribute to the overall
antidepressant
effect.
In
humans,
citalopram
does
not
impair
cognitive
(intellectual
function)
and
ps