ADVANCED DNA MEDICATED COLLECTION lidocaine hydrochloride glycerin

البلد: الولايات المتحدة

اللغة: الإنجليزية

المصدر: NLM (National Library of Medicine)

العنصر النشط:

LIDOCAINE HYDROCHLORIDE (UNII: V13007Z41A) (LIDOCAINE - UNII:98PI200987)

متاح من:

Asclemed USA, Inc

INN (الاسم الدولي):

LIDOCAINE HYDROCHLORIDE

تركيب:

LIDOCAINE HYDROCHLORIDE ANHYDROUS 20 mg in 1 mL

نوع الوصفة الطبية :

PRESCRIPTION DRUG

الوضع إذن:

unapproved drug other

خصائص المنتج

ADVANCED DNA MEDICATED COLLECTION- LIDOCAINE HYDROCHLORIDE, GLYCERIN
ASCLEMED USA, INC
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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LIDOCAINE HYDROCHLORIDE ORAL TOPICAL SOLUTION, USP (VISCOUS) 2%
A Topical Anesthetic for the Mucous Membranes of the Mouth and
Pharynx.
FOR ORAL USE ONLY.
RX ONLY
DESCRIPTION
Lidocaine Hydrochloride Oral Topical Solution, USP (Viscous) 2%
contains a local anesthetic agent
and is administered topically. Lidocaine Hydrochloride Oral Topical
Solution, USP (Viscous) 2%
contains lidocaine hydrochloride, which is chemically designated as
acetamide, 2-(diethylamino)-N-
(2,6-dimethylphenyl)- , monohydrochloride and has the following
structural formula:
The molecular formula of lidocaine is C
H N O. The molecular weight is 234.34.
Each mL contains 20 mg of lidocaine HCl. In addition each mL contains
the following inactive
ingredients: Carboxymethylcellulose sodium, methylparaben, natural
orange flavor, propylparaben,
purified water, saccharin sodium. The pH is adjusted to 5.0 to 7.0 by
means of hydrochloric acid and/or
sodium hydroxide.
CLINICAL PHARMACOLOGY
MECHANISM OF ACTION:
Lidocaine stabilizes the neuronal membrane by inhibiting the ionic
fluxes required for the initiation and
conduction of impulses, thereby effecting local anesthetic action.
HEMODYNAMICS :
Excessive blood levels may cause changes in cardiac output, total
peripheral resistance, and mean
arterial pressure. These changes may be attributable to a direct
depressant effect of the local anesthetic
agent on various components of the cardiovascular system. The net
effect is normally a modest
hypotension when the recommended dosages are not exceeded.
PHARMACOKINETICS AND METABOLISM:
Lidocaine is absorbed following topical administration to mucous
membranes, its rate and extent of
absorption being dependent upon concentration and total dose
administered, the specific site of
appli