DEXTROSE 50 % INJECTION

国家: 以色列

语言: 英文

来源: Ministry of Health

有效成分:

GLUCOSE MONOHYDRATE

可用日期:

TEVA MEDICAL LTD

ATC代码:

B05CX01

药物剂型:

SOLUTION FOR INFUSION

组成:

GLUCOSE MONOHYDRATE 50 %

给药途径:

I.V

处方类型:

Required

厂商:

TEVA MEDICAL LTD, ISRAEL

治疗组:

GLUCOSE

治疗领域:

GLUCOSE

疗效迹象:

Dextrose 50 % injection is indicated as a caloric component in a parenteral nutrition regimen. It is used with an appropriate protein (nitrogen) source in the prevention of nitrogen loss or in the treatment of negative nitrogen balance in patients where: 1) the alimentary tract cannot/should not be used 2) gastrointestinal absorption of protein is impaired or 3) metabolic requirements for protein are substantially increased , as with extensive burns.

授权日期:

2010-04-30

产品特点

DEXTRLOC 10. 3. 2004 , RH
"
ע עבקנ הז ןולע טמרופ
"
ודי לע רשואו קדבנ ונכותו תואירבה דרשמ
י
20%, 50% Dextrose Injections
(Dextrose in Water) in Plastic Bags.
PARENTERAL NUTRIENTS
Description
20%
and
50%
Dextrose
injections
are
sterile,
nonpyrogenic
and
hypertonic
solutions. They contain Dextrose in Water for Injection. The pH of the
50% Dextrose
injection is adjusted with hydrochloric acid. Neither solution
contains any antimicrobial
agent or buffer. The composition, osmolarity, pH and calorie content
are shown in
Table 1 below:
Table 1
Composition, Osmolarity, Approximate pH Values, and Calories per Liter
COMPOSITION
Dextrose
hydrous (g/L)
Osmolarity
(mOsm/L)
Calculated
Approx. pH
Values
Calorie
Content
(Kcal/L)
20% Dextrose
Injection
200
1010
4.5
(3.5-6.5)
684
50% Dextrose
Injection
500
2520
4.0
(3.5-6.5)
1710
The plastic bag is fabricated from a specially formulated polyvinyl
chloride. Water
can permeate from inside the bag into the overwrap in amounts
insufficient to affect
the solution significantly. Solutions in contact with the plastic bag
can leach out certain
of its chemical components in very small amounts within the expiration
period, e.g., di-
2-ethylhexyl phthalate (DEHP), up to 5 parts per million. However, the
safety of the
plastic has been confirmed in tests in animals according to USP
biological standards
for plastic containers as well as by tissue culture toxicity studies.
Clinical Pharmacology
Dextrose injections have value as a source of water and calories. They
are capable
of inducing diuresis depending on the clinical condition of the
patient.
Indications
20% and 50% Dextrose Injections are indicated as a caloric component
in a
parenteral nutrition regimen. They are used with an appropriate
protein (nitrogen)
source in the prevention of nitrogen loss or in the treatment of
negative nitrogen
balance in patients where:
(1)
the alimentary tract cannot or should not be used
(2)
gastrointestinal absorption of protein is impaired, or
(3)
metabolic req