Canesten Fluconazole
国家: 新西兰
语言: 英文
来源: Medsafe (Medicines Safety Authority)
资料单张 有效成分:
Fluconazole 150mg; Fluconazole 150mg
可用日期:
Bayer New Zealand Limited
INN（国际名称）:
Fluconazole 150 mg
剂量:
150 mg
药物剂型:
Capsule
组成:
Active: Fluconazole 150mg Fluconazole 150mg
每包单位数:
Blister pack, PVC/PVdC/Al, 1 capsule
类:
Restricted
处方类型:
Restricted
厂商:
Mylan Laboratories Limited
疗效迹象:
Canesten Fluconazole Capsule, given orally, is indicated for vaginal candidiasis.
產品總結:
Package - Contents - Shelf Life: Blister pack, PVC/Al or PVC/PVdC/Al - 1 capsules - 36 months from date of manufacture stored at or below 25°C
授权日期:
2006-03-03
资料单张
_Canesten Fluconazole CMI _
_19 May 2009_
Consumer Medicine Information
1
CANESTEN
FLUCONAZOLE CAPSULE
FLUCONAZOLE ORAL CAPSULE 150 MG
WHAT IS IN THIS LEAFLET
This leaflet answers some
common questions about Canesten Fluconazole Capsule.
It does not contain all the available information. It does
not take the place of talking to your
doctor or pharmacist.
All medicines have risks and
benefits. Your pharmacist has weighed the risks of you using
Canesten Fluconazole
Capsule against the benefits they expect it will have for you.
If you have
any concerns about using this medicine, ask your doctor or pharmacist.
KEEP THIS LEAFLET WITH THE MEDICINE.
You may need to read it again.
WHAT CANESTEN FLUCONAZOLE CAPSULE IS USED FOR
Canesten Fluconazole
Capsule is used to treat a fungal infection
in the vagina (vaginal
thrush).
This medicine belongs to a group of medicines called azole
antifungals.
Canesten Fluconazole Capsule is taken by mouth and
works from the inside to prevent the
growth of the fungi causing your infection.
_WHAT IS VAGINAL THRUSH? _
Vaginal thrush is the common name for vaginal candidiasis, an infection caused by a
yeast-
like fungus
called _Candida_. _Candida_ can multiply rapidly and cause
damage to the vagina
when other micro-
organisms aren’t present in a normal balance.
Some situations which
can increase susceptibility to thrush are:
diabetes
obesity
illness
fatigue
hormonal fluctuations (pregnancy, menstrual cycle, oral contraceptive
pill, HRT)
prolonged use of antibiotics or steroids
Thrush may cause the following symptoms:
vaginal itching
_Canesten Fluconazole CMI _
_19 May 2009_
Consumer Medicine Information
2
vaginal b
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产品特点
_ _
_ _
_Canesten Fluconazole Data Sheet _
_ _
_ _
_2 April 2009 _
DATA SHEET
1
CANESTEN FLUCONAZOLE CAPSULE
™
FLUCONAZOLE ORAL CAPSULE 150 MG
NAME OF MEDICINE
FLUCONAZOLE
Fluconazole is a bis-triazole: 2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)-2-propanol. It is a white
to off-
white crystalline powder which is sparingly soluble in water and
saline. It has a molecular weight of 306.3.
Structural formula:
DESCRIPTION
Each Canesten Fluconazole Capsule contains fluconazole 150 mg
as the active ingredient.
Size 1 hard gelatin
capsule with white opaque body and white opaque
cap. The body has "FC 150" and the cap
has "G" printed in black. The capsule contains white to
off-white powder. Other ingredients present include
lactose, maize
(corn) starch, sodium lauryl sulphate, colloidal hydrated silica, magnesium stearate,
gelatin and
titanium dioxide (E171).
The ingredients present in the black printing ink used for
coding the capsules include
shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol,
propylene glycol, ammonia solution, potassium
hydroxide and black iron oxide (E172).
PHARMACOLOGY
_ACTIONS _
Fluconazole is a member of the bis-triazole antifungal agents.
Fluconazole is a highly selective inhibitor of fungal
cytochrome P-450 sterol C-14 alpha
demethylation. Mammalian cell demethylation is much
less sensitive to
fluconazole
inhibition. The subsequent loss of normal sterols correlates with the accumulation
of 14 alpha-methyl
sterols in fungi and may be responsible for the
fungistatic activity of fluconazole. Interaction studies with
antipyrine
indicate that single or multiple doses of fluconazole 50 mg do
not affect its metabolism.
_PHARMACOKINETICS _
Fluconazole is well absorbed and oral absorption is not affected
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