Страна: США
мова: англійська
Джерело: NLM (National Library of Medicine)
SPINOSAD (UNII: XPA88EAP6V) (SPINOSAD - UNII:XPA88EAP6V)
Elanco Animal Health Co
SPINOSAD
SPINOSAD 140 mg
PRESCRIPTION
New Animal Drug Application
TRIFEXIS- SPINOSAD AND MILBEMYCIN OXIME TABLET, CHEWABLE ELANCO ANIMAL HEALTH CO ---------- TRIFEXIS (SPINOSAD + MILBEMYCIN OXIME) CHEWABLE TABLETS CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. DES CRIPTION: TRIFEXIS (spinosad and milbemycin oxime) is available in five sizes for oral administration to dogs and puppies according to their weight. Each chewable flavored tablet is formulated to provide a minimum spinosad dose of 13.5 mg/lb (30 mg/kg) and a minimum milbemycin oxime dose of 0.2 mg/lb (0.5 mg/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, _Saccharopolyspora spinosa_. Spinosyn A and spinosyn D have the chemical compositions C H NO and C H NO , respectively. Milbemycin oxime is a macrocyclic lactone anthelmintic, containing two major factors, A and A of milbemycin oxime. The approximate ratio of A :A is 20:80. Milbemycin A 5-oxime has the chemical composition of C H NO and milbemycin A 5-oxime has the chemical composition of C H NO . INDICATIONS : TRIFEXIS is indicated for the prevention of heartworm disease (_Dirofilaria immitis_). TRIFEXIS kills fleas and is indicated for the prevention and treatment of flea infestations (_Ctenocephalides felis_), and the treatment and control of adult hookworm (_Ancylostoma caninum_), adult roundworm (_Toxocara canis_ and _Toxascaris leonina_) and adult whipworm (_Trichuris vulpis_) infections in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater. DOSAGE AND ADMINISTRATION: TRIFEXIS is given orally, once a month at the minimum dosage of 13.5 mg/lb (30 mg/kg) spinosad and 0.2 mg/lb (0.5 mg/kg) milbemycin oxime body weight. For heartworm prevention, give once monthly for at least 3 months after exposure to mosquitoes (see EFFECTIVENESS). _Dosage Schedule:_ Body Weight Spinosad Per Tablet (mg) Milbemycin oxime Прочитайте повний документ