PREDNISONE tablet

Страна: Соединенные Штаты

Язык: английский

Источник: NLM (National Library of Medicine)

Активный ингредиент:

PREDNISONE (UNII: VB0R961HZT) (PREDNISONE - UNII:VB0R961HZT)

Доступна с:

Bryant Ranch Prepack

Администрация маршрут:

ORAL

Тип рецепта:

PRESCRIPTION DRUG

Терапевтические показания :

Prednisone tablets are indicated in the following conditions: 1. Endocrine Disorders Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy mineralocorticoid supplementation is of particular importance) Congenital adrenal hyperplasia Hypercalcemia associated with cancer Nonsuppurative thyroiditis 2. Rheumatic Disorders As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in: Psoriatic arthritis Rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy) Ankylosing spondylitis Acute and subacute bursitis Acute nonspecific tenosynovitis Acute gouty arthritis Post-traumatic osteoarthritis Synovitis of osteoarthritis Epicondylitis 3. Collagen Diseases During an exacerbation or as maintenance therapy in selected cases of: Systemic lupu

Обзор продуктов:

NDC: 71335-1736-7: 24 Tablets in a BOTTLE, PLASTIC NDC: 71335-1736-1: 6 Tablets in a BOTTLE, PLASTIC NDC: 71335-1736-2: 14 Tablets in a BOTTLE, PLASTIC NDC: 71335-1736-3: 5 Tablets in a BOTTLE, PLASTIC NDC: 71335-1736-4: 10 Tablets in a BOTTLE, PLASTIC NDC: 71335-1736-5: 8 Tablets in a BOTTLE, PLASTIC NDC: 71335-1736-6: 7 Tablets in a BOTTLE, PLASTIC

Статус Авторизация:

Abbreviated New Drug Application

Характеристики продукта

PREDNISONE- PREDNISONE TABLET
BRYANT RANCH PREPACK
----------
PREDNISONE TABLETS, USP
DESCRIPTION
Prednisone tablets contain prednisone which is a glucocorticoid.
Glucocorticoids are
adrenocortical steroids, both naturally occurring and synthetic, which
are readily
absorbed from the gastrointestinal tract. Prednisone is a white to
practically white,
odorless, crystalline powder. It is very slightly soluble in water;
slightly soluble in alcohol,
in chloroform, in dioxane, and in methanol.
The chemical name for prednisone is
pregna-1,4-diene-3,11,20-trione,17,21-dihydroxy-
and its molecular weight is 358.43.
The structural formula is represented below:
Prednisone tablets are available in 3 strengths:10 mg, 20 mg and 50
mg. Inactive
ingredients: Colloidal Silicon Dioxide, Lactose Monohydrate, Cellulose
Powder, Magnesium
Stearate, and Croscarmellose Sodium.
CLINICAL PHARMACOLOGY
Naturally occurring glucocorticoids (hydrocortisone and cortisone),
which also have salt-
retaining properties, are used as replacement therapy in
adrenocortical deficiency
states. Their synthetic analogs are primarily used for their potent
anti-inflammatory
effects in disorders of many organ systems.
Glucocorticoids cause profound and varied metabolic effects. In
addition, they modify
the body's immune responses to diverse stimuli.
INDICATIONS AND USAGE
Prednisone tablets are indicated in the following conditions:
1. ENDOCRINE DISORDERS
Primary or secondary adrenocortical insufficiency (hydrocortisone or
cortisone is the
first choice; synthetic analogs may be used in conjunction with
mineralocorticoids where
applicable; in infancy mineralocorticoid supplementation is of
particular importance)
Congenital adrenal hyperplasia
Hypercalcemia associated with cancer
Nonsuppurative thyroiditis
2. RHEUMATIC DISORDERS
As adjunctive therapy for short-term administration (to tide the
patient over an acute
episode or exacerbation) in:
Psoriatic arthritis
Rheumatoid arthritis, including juvenile rheumatoid arthritis
(selected cases may require
low-dose ma