Country: Stati Uniti
Lingwa: Ingliż
Sors: NLM (National Library of Medicine)
HYOSCYAMINE SULFATE (UNII: F2R8V82B84) (HYOSCYAMINE - UNII:PX44XO846X)
Method Pharmaceuticals, LLC
ORAL
PRESCRIPTION DRUG
Hyoscyamine sulfate is effective as adjunctive therapy in the treatment of peptic ulcer. It can also be used to control gastric secretion, visceral spasm and hypermotility in spastic colitis, spastic bladder, cystitis, pylorospasm, and associated abdominal cramps. May be used in functional intestinal disorders to reduce symptoms such as those seen in mild dysenteries, diverticulitis, and acute enterocolitis. For use as adjunctive therapy in the treatment of irritable bowel syndrome (irritable colon, spastic colon, mucous colitis) and functional gastrointestinal disorders. Also used as adjunctive therapy in the treatment of neurogenic bladder and neurogenic bowel disturbances (including the splenic flexure syndrome and neurogenic colon). Also used in the treatment of infant colic (elixir and drops). Hyoscyamine sulfate is indicated along with morphine or other narcotics in symptomatic relief of biliary and renal colic; as a “drying agent” in the relief of symptoms of acute rhinitis; in the therapy of parkinson
Hyoscyamine Sulfate Elixir (0.125 mg per 5 mL) is clear colored, grape flavored and contains no alcohol or sugar. It is supplied in 16 fl. Oz. (473 mL) bottles (NDC 58657-427-16). Store at controlled room temperature, 15°-30°C (59°-86°F). Rx Only. Distributed by: Method Pharmaceuticals, LLC Fort Worth, TX 76118 Rev. Date: 08/2019
unapproved drug other
HYOSCYAMINE SULFATE- HYOSCYAMINE SULFATE ELIXIR METHOD PHARMACEUTICALS, LLC _Disclaimer: This drug has not been found by FDA to be safe and effective, and this_ _labeling has not been approved by FDA. For further information about unapproved_ _drugs, click here._ ---------- HYOSCYAMINE SULFATE HYOSCYAMINE SULFATE ELIXIR RX ONLY DESCRIPTION Hyoscyamine Sulfate Elixir contains 0.125 mg hyoscyamine sulfate per 5 mL that is alcohol free and sugar free for oral administration. Hyoscyamine sulfate is one of the principal anticholinergic/antispasmodic components of belladonna alkaloids. The empirical formula is (C H NO ) •H SO •2H O and the molecular weight is 712.85. Chemically, it is benzeneacetic acid, (a-(hydroxymethyl)-, 8- methyl-8-azabicyclo[3.2.1.]oct-3-yl ester, [3(S)- endo]-, sulfate (2:1), dihydrate with the following structure: HYOSCYAMINE SULFATE ELIXIR also contain as inactive ingredients: Purified Water, Glycerin, Methylparaben Sodium, Propylparaben Sodium, Saccharin Sodium, Xylitol, Citric Acid, Stevia Reb-A, Natural and Artificial Grape Flavor. CLINICAL PHARMACOLOGY Hyoscyamine sulfate inhibits specifically the actions of acetylcholine on structures innervated by postganglionic cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation. These peripheral cholinergic receptors are present in the autonomic effector cells of the smooth muscle, cardiac muscle, the sinoatrial node, the atrioventricular node, and the exocrine glands. At therapeutic doses, it is completely devoid of any action on autonomic ganglia. Hyoscyamine sulfate inhibits gastrointestinal propulsive motility and decreases gastric acid secretion. Hyoscyamine sulfate also controls excessive pharyngeal, tracheal and bronchial secretions. Hyoscyamine sulfate is absorbed totally and completely by oral administration. Once absorbed, hyoscyamine sulfate disappears rapidly from the blood and is distributed throughout the entire body. The half-life of hyoscyamine sulfate is 2 to 3 1/2 hours. Hyoscyam Aqra d-dokument sħiħ