Country: Amerika Syarikat
Bahasa: Inggeris
Sumber: NLM (National Library of Medicine)
TORSEMIDE (UNII: W31X2H97FB) (TORSEMIDE - UNII:W31X2H97FB)
Direct_Rx
ORAL
PRESCRIPTION DRUG
1.1 Edema Torsemide tablets are indicated for the treatment of edema associated with heart failure, renal disease or hepatic disease. 1.2 Hypertension Torsemide tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including the class to which this drug principally belongs. There are no controlled trials demonstrating risk reduction with torsemide tablets. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than one drug to achieve blood pressure goals. For specific advice on goals and management, see published guideli
Torsemide tablets USP, 5 mg are white to off white, oval shaped, scored tablets, debossed with ‘56’ on scored side and ‘H’ on the opposite side. They are supplied as follows: 31722-529-01, bottle of 100 31722-529-05, bottle of 500 Torsemide tablets USP, 10 mg are white to off white, oval shaped, scored tablets, debossed with ‘57’ on scored side and ‘H’ on the opposite side. They are supplied as follows: 31722-530-01, bottle of 100 31722-530-05, bottle of 500 Torsemide tablets USP, 20 mg are white to off white, oval shaped, scored tablets, debossed with ‘59’ on scored side and ‘H’ on the opposite side. They are supplied as follows: 31722-531-01, bottle of 100 31722-531-05, bottle of 500 Torsemide tablets USP, 100 mg are white to off white, oval shaped, scored tablets, debossed with ‘60’ on scored side and ‘H’ on the opposite side. They are supplied as follows: 31722-532-01, bottle of 100 31722-532-05, bottle of 500 Storage Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]
Abbreviated New Drug Application
TORSEMIDE- TORSEMIDE TABLET DIRECT_RX ---------- TORSEMIDE 1.1 Edema Torsemide tablets are indicated for the treatment of edema associated with heart failure, renal disease or hepatic disease. 1.2 Hypertension Torsemide tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including the class to which this drug principally belongs. There are no controlled trials demonstrating risk reduction with torsemide tablets. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than one drug to achieve blood pressure goals. For specific advice on goals and management, see published guidelines, such as those of the National High Blood Pressure Education Program’s Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC). Numerous antihypertensive drugs, from a variety of pharmacologic classes and with different mechanisms of action, have been shown in randomized controlled trials to reduce cardiovascular morbidity and mortality, and it can be concluded that it is blood pressure reduction, and not some other pharmacologic property of the drugs, that is largely responsible for those benefits. The largest and most consistent cardiovascular outcome benefit has been a reduction in the risk of stroke, but reductions in myocardial infarction and cardiovascular mortality also have been seen regularly. Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mmHg is greater at higher blood pressures, so that even modest reductions of severe Baca dokumen lengkap