Dyna Doxycycline Capsule 100mg

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

DOXYCYCLINE HYDROCHLORIDE/HYCLATE

Boleh didapati daripada:

DYNAPHARM (M) SDN BHD

INN (Nama Antarabangsa):

DOXYCYCLINE HYDROCHLORIDE/HYCLATE

Unit dalam pakej:

100 Capsules; 1000 Capsules; 500 Capsules; 10 Capsules

Dikeluarkan oleh:

DYNAPHARM (M) SDN BHD

Risalah maklumat

Consumer Medication Information Leaflet (RiMUP)
DYNA DOXYCYCLINE CAPSULE 100MG
Doxycycline HCl (100 mg)
Page 1 of 2
What is in this leaflet
1.
What Dyna Doxycycline Capsule
100mg is used for
2.
How Dyna Doxycycline Capsule
100mg works
3.
Before you used Dyna Doxycycline
Capsule 100mg
4.
How to use Dyna Doxycycline
Capsule 100mg
5.
While you are using it
6.
Side effects
7.
Storage and disposal of Dyna
Doxycycline Capsule 100mg
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10.
Date of revision
What Dyna Doxycycline Capsule
100mg is used for
Indicated for the treatment of variety of
infections such as:
1.
Respiratory tract infection;
pneumonia and other lower
respiratory tract infections
2.
Treatment of chronic bronchitis
(inflammation of the lining of
bronchial tubes) and sinusitis
(inflammation of the air cavities
within the passage of the nose)
3.
Urinary tract infections
4.
Sexually transmitted diseases
5.
Skin infections
How Dyna Doxycycline Capsule
100mg works
Mode of action and microbial activity
of Doxycycline HCl similar to
Tetracycline. Doxycycline has a broad
spectrum of anti-microbial activity by
interferes with bacterial protein
synthesis.
Before you use Dyna Doxycycline
Capsule 100mg
-
When you must not use it
Do not use
Dyna Doxycycline Capsule
100mg during pregnancy, in infant and
childhood to the age of 8 years as it
causes tooth discolouration.
Ask your doctor or pharmacists for
advice before taking Dyna Doxycycline
Capsule 100mg.
Pregnancy and lactation
Do not take Dyna Doxycycline Capsule
100mg if you are pregnant, trying to get
pregnant or think you may be pregnant.
Do not take Dyna Doxycycline Capsule
100mg if you are breast-feeding.
-
Before you start to use it
Tell your doctor or pharmacist if you
have hepatic dysfunction.
-
Taking other medicines
Tell your doctor if you are taking any
other medicines, including any that you
buy without a prescriptions from a
pharmacy, supermarket or health food
shop.
Avoid concomitant use with antacids,
mineral supplements such as ir

Ciri produk

DYNA DOXYCYCLINE CAPSULE 100MG
MAL19984405AZ
DESCRIPTION:
CAPSULE
Capsule Colour : Green/Green
Capsule Size
: # 2
Powder Colour
: Yellow
CONTENT:
Each capsule contains: Doxycycline HCl 115 mg equivalent to
Doxycycline
.....................................................................
100 mg
PHARMACODYNAMICS:
Doxycycline HCI has a broad spectrum of antimicrobial activity. It
interferes with bacterial protein synthesis by reversibly
binding to bacterial 30S ribosomal sub-unit, thus preventing the
binding of aminoacyl transfer RNA to the messenger RNA
ribosome complex. They are usually active against mycoplasmas,
rickettsias, and spirochaetes, and also against many
aerobic and anaerobic Gram positive and Gram negative pathogenic
bacteria, and some protozoa. Although the microbial
activity and mode of action of Doxycycline HCI is similar to
Tetracycline, it is more effective than Tetracycline against many
species.
PHARMACOKINETICS:
Doxycycline HCI is readily absorbed from the gastrointestinal tract
and absorption is not significantly affected by the presence
of food in the stomach or duodenum. Mean peak plasma concentrations of
2.6
µ
g per ml have been reported 2 hours after a
200 mg dose by mouth, falling to 1.45
µ
g per ml at 24 hours. Following repeated doses of 100 mg daily,
concentrations of
about 2
µ
g per ml are maintained. Similar values are reported after intravenous
infusions. From 80 to 95% of Doxycycline in
the circulation is reported to be bound to plasma proteins. Its
biological half-life varies from about 15 to 22 hours. Doxycycline
is more lipid-soluble than Tetracycline. It is widely distributed in
body tissues and fluids but only low concentrations are
achieved in cerebrospinal fluid. Doxycycline is slowly excreted in the
urine and it is also excreted in the faeces following
chelation in the intestines. There is also some inactivation in the
liver. It is stated not to accumulate significantly in patients with
renal impairment although excretion in the urine is reduced; increased
amounts of Dox