TRIFEXIS spinosad and milbemycin oxime tablet chewable

Pays: États-Unis

Langue: anglais

Source: NLM (National Library of Medicine)

Ingrédients actifs:

SPINOSAD (UNII: XPA88EAP6V) (SPINOSAD - UNII:XPA88EAP6V)

Disponible depuis:

Elanco Animal Health Co

DCI (Dénomination commune internationale):

SPINOSAD

Composition:

SPINOSAD 140 mg

Type d'ordonnance:

PRESCRIPTION

Statut de autorisation:

New Animal Drug Application

Résumé des caractéristiques du produit

TRIFEXIS- SPINOSAD AND MILBEMYCIN OXIME TABLET, CHEWABLE
ELANCO ANIMAL HEALTH CO
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TRIFEXIS
(SPINOSAD + MILBEMYCIN OXIME)
CHEWABLE TABLETS
CAUTION: Federal (USA) law restricts this drug to use by or on the
order of a licensed veterinarian.
DES CRIPTION:
TRIFEXIS (spinosad and milbemycin oxime) is available in five sizes
for oral administration to dogs
and puppies according to their weight. Each chewable flavored tablet
is formulated to provide a
minimum spinosad dose of 13.5 mg/lb (30 mg/kg) and a minimum
milbemycin oxime dose of 0.2 mg/lb
(0.5 mg/kg). Spinosad is a member of the spinosyns class of
insecticides, which are non-antibacterial
tetracyclic macrolides. Spinosad contains two major factors, spinosyn
A and spinosyn D, derived from
the naturally occurring bacterium, _Saccharopolyspora spinosa_.
Spinosyn A and spinosyn D have the
chemical compositions C
H NO and C
H NO , respectively. Milbemycin oxime is a
macrocyclic lactone anthelmintic, containing two major factors, A and
A of milbemycin oxime. The
approximate ratio of A :A is 20:80. Milbemycin A 5-oxime has the
chemical composition of
C
H NO and milbemycin A 5-oxime has the chemical composition of C
H NO .
INDICATIONS :
TRIFEXIS is indicated for the prevention of heartworm disease
(_Dirofilaria immitis_). TRIFEXIS kills
fleas and is indicated for the prevention and treatment of flea
infestations (_Ctenocephalides felis_), and the
treatment and control of adult hookworm (_Ancylostoma caninum_), adult
roundworm (_Toxocara canis_ and
_Toxascaris leonina_) and adult whipworm (_Trichuris vulpis_)
infections in dogs and puppies 8 weeks of age
or older and 5 pounds of body weight or greater.
DOSAGE AND ADMINISTRATION:
TRIFEXIS is given orally, once a month at the minimum dosage of 13.5
mg/lb (30 mg/kg) spinosad and
0.2 mg/lb (0.5 mg/kg) milbemycin oxime body weight. For heartworm
prevention, give once monthly for
at least 3 months after exposure to mosquitoes (see EFFECTIVENESS).
_Dosage Schedule:_
Body Weight
Spinosad
Per Tablet (mg)
Milbemycin oxime