Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

nippon kayaku co ltd - paradichlorobenzene; propetamphos; hydrocarbon solvent - medicated dressing, topical device - paradichlorobenzene benzene active 400.0 g/l; propetamphos organophosphorus active 14.4 g/l; hydrocarbon solvent solvent other 510.0 g/l - parasiticides - sheep | ewe | hogget | lamb | ovine | ram | weaner | wether - blowfly maggot - calliphoridae

United States - English - NLM (National Library of Medicine)

corcept therapeutics incorporated - mifepristone (unii: 320t6rnw1f) (mifepristone - unii:320t6rnw1f) - mifepristone 300 mg - korlym (mifepristone) is a cortisol receptor blocker indicated to control hyperglycemia secondary to hypercortisolism in adult patients with endogenous cushing's syndrome who have type 2 diabetes mellitus or glucose intolerance and have failed surgery or are not candidates for surgery. limitations of use: - korlym should not be used in the treatment of patients with type 2 diabetes unless it is secondary to cushing's syndrome. korlym is contraindicated in: - pregnancy [see dosage and administration (2.1), use in specific populations (8.1,8.3)] - patients taking drugs metabolized by cyp3a such as simvastatin, lovastatin, and cyp3a substrates with narrow therapeutic ranges, such as cyclosporine, dihydroergotamine, ergotamine, fentanyl, pimozide, quinidine, sirolimus, and tacrolimus, due to an increased risk of adverse events. [see drug interactions (7.1) and clinical pharmacology (12.3)] - patients receiving systemic corticosteroids for lifesaving purposes (e.g., immunosuppression after organ transplantation) because korlym antagonizes the effect of glucocorticoids. - women with a history of unexplained vaginal bleeding or with endometrial hyperplasia with atypia or endometrial carcinoma. - patients with known hypersensitivity to mifepristone or to any of the product components. risk summary korlym is contraindicated in pregnancy because the use of korlym results in pregnancy loss. there are no data that assess the risk of birth defects in women exposed to korlym during pregnancy. available data limited to exposure following a single dose of mifepristone during pregnancy showed a higher rate of major birth defects compared to the general population comparator (see data) . mifepristone administered to pregnant mice, rats, and rabbits during organogenesis caused pregnancy loss in all species at clinically relevant doses based on body surface area comparisons (see data) . the inhibition of both endogenous and exogenous progesterone by mifepristone at the progesterone receptor results in pregnancy loss. if korlym is used during pregnancy or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to a fetus. [see contraindications (4)] the estimated risk of fetal loss is elevated in patients with active cushing's syndrome (24-30%), and the risk of major birth defects is unknown. in the u.s. general population, the estimated background risks of major birth defects and miscarriage in clinically recognized pregnancies are 2-4% and 15-20%, respectively. data human data there are no data on long term exposure to mifepristone in pregnancy. available data are limited to exposure to a single dose of mifepristone for pregnancy termination. in a prospective study in france of 46 pregnancies exposed to a single dose of mifepristone alone and 59 pregnancies exposed to a single dose of mifepristone and misoprostol, the overall major birth defect rate (4%) was greater than the general population background rate of 2 to 3% (2 birth defects in each group). there was no pattern of birth defects identified. animal data reproductive studies were performed in mice, rats and rabbits at doses of 0.25 to 4.0 mg/kg (less than human exposure at the maximum clinical dose, based on body surface area). because of the anti-progestational activity of mifepristone, fetal losses were much higher than in control animals. skull deformities were detected in rabbit studies at less than human exposure, although mifepristone did not cause any adverse developmental effects in rats or mice during organogenesis. these deformities were most likely due to the mechanical effects of uterine contractions resulting from antagonism of the progesterone receptor. risk summary mifepristone is present in human milk, however, there are no data on the amount of mifepristone in human milk, the effects on the breastfed infant, or the effects on milk production during long term use of mifepristone (see data) . the developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for korlym and any potential adverse effects on the breastfed child from korlym or from the underlying maternal condition. clinical considerations to minimize exposure to a breastfed infant, women who discontinue or interrupt korlym treatment may consider pumping and discarding milk during treatment and for 18-21 days (5-6 half-lives) after the last dose, before breastfeeding. data available published data based on intake of a single dose of 600 mg of mifepristone in 10 breastfeeding women who were 6-12 months postpartum showed a small amount in breast milk (the estimated relative infant dose was 0.5%). the half-life of mifepristone is longer with repeat dosing compared to a single dose; therefore, there may be greater exposure with long term use. pregnancy testing due to its anti-progestational activity, korlym causes pregnancy loss. perform pregnancy testing before the initiation of treatment with korlym or if treatment is interrupted for more than 14 days in females of reproductive potential. contraception recommend non-hormonal contraception for the duration of treatment and for one month after stopping treatment . korlym interferes with the effectiveness of hormonal contraceptives. [see drug interactions (7.6)] safety and effectiveness of korlym in pediatric patients have not been established. clinical studies with korlym did not include sufficient numbers of patients aged 65 and over to determine whether they respond differently than younger people. the maximum dose should not exceed 600 mg per day in renally impaired patients. [see clinical pharmacology (12.3)] in patients with mild to moderate hepatic impairment, the maximum dose should not exceed 600 mg per day. the pharmacokinetics of mifepristone in patients with severe hepatic impairment has not been studied, and korlym should not be used in these patients. [see clinical pharmacology (12.3)]

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

kenso corporation (m) sdn. bhd. - trifluralin; liquid hydrocarbon - emulsifiable concentrate - trifluralin anilide/aniline-dinitro active 480.0 g/l; liquid hydrocarbon solvent other 475.0 g/l - herbicide - adzuki bean | annual medic seed crop | barley | barley - prior to sowing | barley - prior to sowing & incorporated | barley pre& - amaranth or amaranthus | amsinckia,yellow burrweed or burr grass | annual broadleaf weed | annual grass weed | annual phalaris | annual ryegrass | annual ryegrass - seed | annual ryegrass - suppression | barley grass | barnyard grass or water grass | barnyard or water grass | barnyard or water grass - seed | brome grass | brome grass - suppression | button grass | caltrop or yellow vine | caltrop or yellow vine - seed | caltrop or yellow vine - suppression | canary grass | capeweed | cereal oat | cereal oats - suppression | climbing buckwheat - suppression | columbus grass - seed | common fumitory | corn gromwell, ironweed or sheepweed | crowsfoot grass | deadnettle | deadnettle - suppression | doublegee - suppression | fumitory | fumitory - red | fumitory - seed | fumitory - suppression | fumitory - white | geranium | giant or black pigweed | guinea grass - seed | iceplant - suppression | indian hedge mustard | innocent weed or grass | ivy leaf speedwell | johnson grass - seed | liverseed grass - seed | love

United States - English - NLM (National Library of Medicine)

bausch & lomb incorporated - hydroxypropyl cellulose (1600000 wamw) (unii: rfw2et671p) (hydroxypropyl cellulose (1600000 wamw) - unii:rfw2et671p) - hydroxypropyl cellulose (type h) 5 mg - lacrisert is indicated in patients with moderate to severe dry eye syndromes, including keratoconjunctivitis sicca. lacrisert is indicated especially in patients who remain symptomatic after an adequate trial of therapy with artificial tear solutions. lacrisert is also indicated for patients with: lacrisert is contraindicated in patients who are hypersensitive to hydroxypropyl cellulose. clinical experience with lacrisert indicates that in some patients several weeks may be required before satisfactory improvement of symptoms is achieved. two applicators (one spare) are supplied with each package. preparing to insert lacrisert before opening the package of lacrisert, wash your hands thoroughly with soap and water. step 1: on a flat surface, open blister pocket slowly and smoothly by peeling back label area. each blister pocket contains one lacrisert ophthalmic insert. step 2: open applicator package with label side up. avoid touching grooved tip of the applicator. pick up applicator by the wide end and rinse the tip thoroughly under hot running tap water. gently shake off excess water. step 3: hold applicator with tip facing down and with forefinger on top to guide and apply gentle pressure. lightly press the grooved tip of the applicator onto the lacrisert ophthalmic insert and it will adhere to the applicator. it is important to follow steps 4 and 5 carefully or you might experience difficulty in keeping lacrisert (hydroxypropyl cellulose ophthalmic insert) in your eye. step 4: look into a mirror. starting with the right eye, turn your head to the right so that the colored part of the eye is close to your nose. use your free hand to grasp the lower lid between the thumb and index finger. pull the lid away from the eyeball and create a pocket between the white part of the eyeball and the lid. step 5: place the tip of the applicator containing lacrisert into the pocket. avoid touching the colored part of the eye. remove the applicator. it is important, after removing the applicator, to look down, then release the lower eyelid. lacrisert (hydroxypropyl cellulose ophthalmic insert) should remain deep in the lower pocket recess of the eye and not near the edge of the lower eyelid. repeat procedure with left eye, turning head to the left so that the colored part of the eye is close to your nose. rinse the applicator thoroughly under hot running tap water after use. gently shake off visible water droplets and promptly return it to the storage container. note that the storage container provides space for a strip of two lacrisert ophthalmic inserts next to the applicator storage compartment. important if lacrisert causes worsening of symptoms, or if new symptoms develop, it should be removed and your prescriber contacted. should the removal of the lacrisert ophthalmic insert be necessary, follow these instructions. caution: because this product may produce transient blurring of vision, you should exercise caution when operating hazardous machinery or driving a motor vehicle. store below 86°f (30°c) distributed by: bausch + lomb, a division of bausch health us, llc bridgewater, nj 08807 usa manufactured by: renaissance lakewood, llc, lakewood, nj 08701 usa this instructions for use has been approved by the u.s. food and drug administration. lacrisert is a trademark of bausch & lomb incorporated or its affiliates. © 2019 bausch & lomb incorporated or its affiliates 9421304 revised: 10/2019

Armenia - English - Դեղերի և բժշկական տեխնոլոգիաների փորձագիտական կենտրոնի գործունեության Հայաստանի Հանրապետությունում

reyoung pharmaceutical co. ltd. - cefuroxime (cefuroxime sodium) - powder for solution for injection/infusion - 750mg

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

keyport nominees - trifluralin(480g/l) - emulsifiable - group d herbicide - adzuki bean | annual medic seed crop | barley | barley - prior to sowing | barley - prior to sowing & incorporated | barley pre& - amaranth or amaranthus | annual broadleaf weeds & grasses-see lab | annual phalaris | annual ryegrass | annual ryegrass - suppression | barley grass | barnyard or water grass | black bindweed | brome grass | brome grass - suppression | button grass | caltrop or yellow vine | caltrop or yellow vine - suppression | canary grass | capeweed | cereal oat | climbing buckwheat - suppression | columbus grass - seed | common fumitory | corn gromwell, ironweed or sheepweed | crowsfoot grass | deadnettle | deadnettle - suppression | fumitory | fumitory - red | fumitory - suppression | fumitory - white | geranium | giant or black pigweed | guinea grass - seed | iceplant - suppression | indian hedge mustard | innocent weed or grass | ivy leaf speedwell | johnson grass - seed | liverseed grass - seed | lovegrass | mossman river or burr grass | mustard | paradoxa grass | phalaris - phalaris spp. | pigweed spp. | radish | red natal grass | redroot or redroot amaranth | redshank - prince of wales feather | rhodes grass | roug

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

cts chemicals pty. ltd. - trifluralin; trifluralin; polyethanoxy (15) tallow amine; liquid hydrocarbon; liquid hydrocarbon; liquid hydrocarbon - emulsifiable concentrate - trifluralin anilide/aniline-dinitro active 480.0 g/l; trifluralin anilide/aniline-dinitro active 480.0 g/l; polyethanoxy (15) tallow amine emulsifiers & surfactants other 3.0 g/l; liquid hydrocarbon solvent other 543.0 g/l; liquid hydrocarbon solvent other 563.0 g/l; liquid hydrocarbon solvent other 474.0 g/l - herbicide - adzuki bean | annual medic seed crop | barley | barley - prior to sowing | barley - prior to sowing & incorporated | barley pre& - amaranth or amaranthus | annual broadleaf weeds & grasses-see lab | annual phalaris | annual ryegrass | annual ryegrass - suppression | barley grass | barnyard or water grass | black bindweed | brome grass | brome grass - suppression | button grass | caltrop or yellow vine | caltrop or yellow vine - suppression | canary grass | capeweed | cereal oat | climbing buckwheat - suppression | columbus grass - seed | common fumitory | corn gromwell, ironweed or sheepweed | crowsfoot grass | deadnettle | deadnettle - suppression | fumitory | fumitory - red | fumitory - suppression | fumitory - white | geranium | giant or black pigweed | guinea grass - seed | iceplant - suppression | indian hedge mustard | innocent weed or grass | ivy leaf speedwell | johnson grass - seed | liverseed grass - seed | lovegrass | mossman river or burr grass | mustard | paradoxa grass | phalaris - phalaris spp. | pigweed spp. | radish | red natal grass | redroot or redroot amaranth | redshank - prince of wales feather | rhodes grass | roug

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

titan ag pty ltd - 2,4-d present as the dimethylamine and diethanolamine sa - soluble concentrate - 2,4-d present as the dimethylamine and diethanolamine sa phenoxy acids-2,4-d active 475.0 g/l - herbicide - agricultural non-crop areas | balansa clover (prior to sowing) | barley | barley - prior to sowing | broom millet | canola (prio - amaranth or amaranthus | amsinckia,yellow burrweed or burr grass | annual thistle | apple-of-peru | artichoke thistle | australian bindweed - seedling | ball mustard | bathurst burr | bellvine - seedling | billygoat weed or blue top | bindweed | bindy-eye | bitou bush or boneseed | blackberry nightshade | bladder ketmia | blue snakeweed | blue top - ageratum/heliotropium spp. | boxthorn | broadleaf weeds - except noogoora burr | burr medic | californian burr | californian thistle | caltrop or yellow vine | caltrop or yellow vine - seedling | camel or afghan melon | canola - brassica napus | cape tulip | capeweed | cat's ear or flatweed | charlock | chinese mint | clockweed | clover | cobbler's pegs | common iceplant | common vetch or tares | convolvulus vines | cotton bush (milky cotton bush) | cowvine | desiccate broadleaf weeds | dock | dock - seedling | doveweed | erodium (storksbill) - seedling | erodium, crowfoot or storksbill | fat hen | fleabane | fumitory - red | fumitory - white | galvanised burr | g

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

titan ag pty ltd - 2,4-d isopropylamine salt - aqueous concentrate - 2,4-d isopropylamine salt phenoxy acids-2,4-d-amine active 300.0 g/l - herbicide - balansa clover (prior to sowing) | barley | barley - prior to sowing | broom millet | canola (prior to sowing) | cereal rye | ce - amaranth or amaranthus | amsinckia | annual ground cherry | annual thistle | apple-of-peru | artichoke thistle | australian bindweed - seedling | ball mustard | bathurst burr | bellvine - seedling | billygoat weed or blue top | bindweed | bindy-eye | bitou bush or boneseed | blackberry nightshade | bladder ketmia | blue snakeweed | blue top - ageratum/heliotropium spp. | boxthorn | broadleaf weeds and grasses - see label | burr medic | californian burr | californian thistle | caltrop or yellow vine | caltrop or yellow vine - seedling | camel or afghan melon | cape tulip | capeweed | cat's ear or flatweed | charlock | chinese mint | clockweed | clover | cobbler's pegs | common iceplant | common pigweed | common storksbill | common vetch or tares | convolvulus vines | cotton bush (milky cotton bush) | cowvine | creeping oxalis | desiccate broadleaf weeds | dock | dock - seedling | doveweed | erodium (storksbill) - seedling | erodium spp. | fat hen | fleabane | fumitory - red | fumitory - white | galvanised burr

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

kenso corporation (m) sdn. bhd. - 2,4-d present as the isopropylamine salt - suspension concentrate - 2,4-d present as the isopropylamine salt phenoxy acids-2,4-d-amine active 450.0 g/l - herbicide - balansa clover (prior to sowing) | barley | barley - prior to sowing | broom millet | canola (prior to sowing) | cereal rye | ch - amaranth or amaranthus | amsinckia | annual ground cherry | annual thistle | apple-of-peru | artichoke thistle | australian bindweed - seedling | ball mustard | bathurst burr | bellvine - seedling | billygoat weed or blue top | bindweed | bindy-eye | bitou bush or boneseed | blackberry nightshade | bladder ketmia | blue snakeweed | boxthorn | broadleaf weeds - except noogoora burr | burr medic | californian burr | californian thistle | caltrop or yellow vine | caltrop or yellow vine - seedling | camel or afghan melon | cape tulip | capeweed | cat's ears or flatweeds | charlock | chinese mint | clockweed | clover | cobbler's pegs | common iceplant | common vetch or tares | convolvulus vines | cotton bush (milky cotton bush) | cowvine | creeping oxalis | desiccate broadleaf weeds | dock | dock - seedling | doveweed | erodium (storksbill) - seedling | erodium, crowfoot or storksbill | fat hen | fleabane | fumitory - red | fumitory - white | galvanised burr | geranium | grasses - except mossman burr | groundsel |