REVOLUTION FOR CATS

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

Buy It Now

Active ingredient:
SELAMECTIN
Available from:
ZOETIS AUSTRALIA PTY LTD
INN (International Name):
selamectin(60mg/mL)
Pharmaceutical form:
TOPICAL SOLUTION/SUSPENSION
Composition:
SELAMECTIN ANTHELMINTIC Active 60.0 mg/ml
Units in package:
1 x 0.75mL; 2 x .075mL; 3 x 0.75mL; 6 x 0.75mL; tubes
Class:
VP - Veterinary Pesticide
Manufactured by:
ZOETIS AUSTRALIA
Therapeutic group:
CAT | RABBIT | ANGORA | BUNNY | CAT - QUEEN | CAT - TOM | KITTEN | LOP EARED
Therapeutic area:
PARASITICIDES
Therapeutic indications:
CATBITING LOUSE | EAR MANGE MITE | FLEA | FLEA ALLERGIC DERMATITIS | FLEA INFESTATIONS | HEARTWORM - PREVENTION OF | HOOKWORM - ANCYLOSTOMA TUBAEFORME | RABBIT EAR MITE | ROUNDWORM - TOXOCARA CATI | SARCOPTIC MANGE | WALKING DANDRUFF MITE (CHEYLETIELLOSIS) | CAT LOUSE | CTENOCEPHALIDES SPP. | EAR MITES | GROUND FLEAS | PSOROPTES HIPPOTIS | TO PREVENT HEARTWORM | TOXOCARA MYSTAX | TREATMENT AND PREVENTION
Product summary:
Poison schedule: 0; Withholding period: WHP: N/A; Host/pest details: CAT: [CATBITING LOUSE, EAR MANGE MITE, FLEA, FLEA ALLERGIC DERMATITIS, FLEA INFESTATIONS, HEARTWORM - PREVENTION OF, HOOKWORM - ANCYLOSTOMA TUBAEFORME, ROUNDWORM - TOXOCARA CATI]; RABBIT: [RABBIT EAR MITE, SARCOPTIC MANGE, WALKING DANDRUFF MITE (CHEYLETIELLOSIS)]; For the treatment &/or control of specified ectoparasites in cats & rabbits (2.6-7.5kg b.w.), control of flea allergy dermatitis in cats, prevention of heartworm disease & treat/control intestinal hookworms & roundworms in cats.Do not use on dogs or cats less than 6 weeks of age. DO NOT USE in rabbits that may be used or processed for human consumption.
Authorization status:
Registered
Authorization number:
50881
Authorization date:
2019-07-01

For Official Use Only

e-Label Application (DRAFT)

Company Name:

ZOETIS AUSTRALIA PTY LTD

Product Name:

REVOLUTION FOR CATS

eLabel Application No:

DC12-93262670E29

APVMA Approval No:

50881/101621

Product No:

50881

Version No:

Application Started:

2015-Apr-22 10:11:40

Version Created:

2015-Jul-21 09:40:47

Started By:

Pamela Hastwell

Printed:

2015-Jul-21 09:49:25

Label Name:

REVOLUTION FOR CATS

Signal Headings:

FOR ANIMAL TREATMENT ONLY

READ SAFETY DIRECTIONS

Constituent

Statements:

60 mg/mL SELAMECTIN

Claims:

For cats and rabbits of 2.6-7.5 kg body weight

Indications:

Kills adult fleas, flea eggs and flea larvae in the environment

Treats, controls and prevents flea infestations in cats

Controls flea allergy dermatitis in cats

Prevents heartworm disease caused by Dirofilaria immitis in cats

Treats and controls ear mites (Otodectes cynotis) in cats. Treats ear mites (Psoroptes

cuniculi) in rabbits

Treats sarcoptic mange (Sarcoptes scabiei) in rabbits

Treats and controls intestinal hookworm (Ancylostoma tubaeforme) and roundworm

(Toxocara cati) in cats

Treats biting lice (Felicola subrostratus) in cats

Treats cheyletiellosis (Cheyletiella sp.) in rabbits

Waterproof after 2 hours in cats

Net Contents:

1 x 0.75mL

2 x 0.75mL

3 x 0.75mL

6 x 0.75mL

tube(s)

It is illegal to sell individual pipettes separately

Directions for Use:

Restraints:

Restraints

DO NOT USE in rabbits that may be used or processed for human consumption

RLP

APPROVED

For Official Use Only

Contraindications:

Contraindications

This product is contraindicated for use on cats less than 6 weeks of age. This product is

contraindicated for use on rabbits less than 8 weeks of age.

Precautions:

Dosage and

Administration:

Apply one (1) tube topically to the skin of cats at the recommended minimum dose of 6 mg

selamectin/kg body weight once a month. The product is for single treatment of rabbits.

1.Remove the REVOLUTION tube from its protective package.

2.Depress the cap to puncture the seal on the REVOLUTION tube; then remove the cap to

apply product.

3.Apply the product directly to the skin without massaging into the site. Part the hair on the

back of the animal in front of the shoulder blades until the skin is visible.

4.Place the tip of the tube on the skin and squeeze the tube to empty its entire contents

directly onto the skin in one spot.

Avoid contact between the product and fingers. Keep away from eyes. Do not apply when

the hair coat is wet. Bathing or shampooing cats two or more hours after treatment will not

reduce the efficacy of REVOLUTION. In rabbits the effect of bathing or shampooing on the

efficacy of REVOLUTION has not been assessed.

General Directions:

NOT TO BE USED FOR ANY PURPOSE, OR IN ANY MANNER, CONTRARY TO THIS

LABEL UNLESS AUTHORISED UNDER APPROPRIATE LEGISLATION.

See attached Part 2

This section contains file attachment.

File Name: General directions Common leaflet Revolution.pdf

File Size: 118330 bytes

Safety Directions:

SAFETY DIRECTIONS:

Will irritate the eyes. Avoid contact with eyes. If product in eyes, wash it out immediately

with water. Wash hands after use. Flammable - Keep away from heat, sparks, open flames

or other sources of ignition.

First Aid

Instructions:

FIRST AID:

If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 13

1126

First Aid Warnings:

Disposal:

Disposal

Dispose of empty tubes by wrapping with paper and placing in the garbage.

Storage:

Storage

Store below 30°C (Room temperature) in the original carton.

[This information is contained in a common leaflet for Revolution products 50867, 50881, 50882.]

READ SAFETY DIRECTIONS

FOR ANIMAL TREATMENT ONLY

REVOLUTION

®

(SELAMECTIN)

Topical Parasiticide for

Dogs, Cats, Puppies, Kittens and Rabbits

The REVOLUTION

range of topical parasiticides contains SELAMECTIN a novel semi-synthetic

compound of the macrocyclic lactone class, in a colourless to pale yellow, ready to use solution. It

is available in colour-coded, single dose tubes for topical (dermal) treatment of dogs and cats

beginning at six weeks of age and rabbits beginning at 8 weeks of age. The content of each tube

is formulated to provide a minimum of 6 mg selamectin/kg body weight.

INDICATIONS:

For the treatment, control and prevention of flea (Ctenocephalides spp.) infestations, control of

flea allergy dermatitis, prevention of heartworm disease caused by Dirofilaria immitis and the

treatment and control of ear mites (Otodectes cynotis) in dogs and cats. For the treatment of ear

mites (Psoroptes cuniculi) in rabbits. For the treatment and control of sarcoptic mange

(Sarcoptes scabiei) in dogs and the treatment of sarcoptic mange in rabbits. For the treatment

and control of intestinal hookworms (Ancylostoma tubaeforme) and roundworms (Toxocara cati)

in cats. For the treatment of lice in dogs and cats including biting (Trichodectes canis) and

sucking lice (Linognathus setosus) in dogs and biting lice in cats (Felicola subrostratus). Also for

the treatment of Cheyletiellia sp. in rabbits.

EFFICACY:

Adult fleas are killed for one month following administration of REVOLUTION according to the

recommended dosing schedule. In addition, flea eggs exposed to this REVOLUTION dosing

schedule are not viable and flea reproduction is stopped. Clinical signs of flea allergy dermatitis

improve after treatment. Monthly administration of REVOLUTION prevents heartworm disease

caused

D.

immitis.

mites

(O.

cynotis)

eliminated

after

single

dose

REVOLUTION in cats and in 90% of dogs after two doses and are controlled by monthly dosing.

Ear mites (Psoroptes cuniculi) in rabbits are eliminated after a single dose. Sarcoptic mange

mites (S. scabiei) in dogs and the common intestinal hookworm (A. tubaeforme) and the

common roundworm (T.cati) in cats, are killed by a single dose of REVOLUTION and controlled

by monthly dosing. Sarcoptic mites (S. scabiei) in rabbits are generally eliminated after one

application

REVOLUTION.

Biting

lice

dogs

(Trichodectes

canis)

cats

(Felicola

subrostratus) are

eliminated

after

single dose.

Sucking

lice (Linognathus

setosus)

eliminated in 90% of dogs by 28 days after a single dose. Cheyletiella sp. mites are eliminated

in rabbits after a single treatment.

DIRECTIONS FOR USE:

Restraints

DO NOT USE in rabbits that may be used or processed for human consumption.

Contraindications

This product is contraindicated for use on dogs,or cats less than 6 weeks of age. This

product is contraindicated for use on rabbits less than 8 weeks of age.

Apply topically to the skin of dogs and cats once a month. For single treatment of rabbits.

DOSAGE:

Animal Type

Weight

Pack Colour

Number of tubes

per month

Puppy, Kitten or

Rabbit

Up to 2.5kg

Mauve

Cat, Rabbit

2.6 – 7.5 kg

Blue

2.6 – 5 kg

Purple

5.1 – 10 kg

Brown

10.1 – 20 kg

20.1 – 40 kg

Teal

Greater than 40 kg

Appropriate combination of tubes

APPLICATION:

Depress the cap to puncture the seal on the REVOLUTION tube; then remove the cap to apply

product.

Apply the product directly to the skin without massaging into the site. Part the hair on the back

of the animal at the base of the neck in front of the shoulder blades until the skin is visible.

Place the tip of the tube on the skin and squeeze the tube to empty its entire contents directly

onto the skin in one spot. Avoid contact between the product and fingers. Do not apply when

the hair coat is wet. Bathing or shampooing dogs or cats 2 or more hours after treatment will

not reduce the efficacy of REVOLUTION. The effect of bathing or shampooing on the efficacy of

REVOLUTION on rabbits has not been assessed.

Flea Treatment, Control and Prevention

If the animal is already infested with fleas when the first dose of REVOLUTION is applied, then

adult fleas on the animal are killed and no viable flea eggs are produced after the first

application. This stops flea reproduction. An environmental infestation of fleas may persist for a

short time after beginning treatment with REVOLUTION because of the emergence of adult

fleas from pre-existing pupae. However, significant reductions in flea infestations are to be

expected after just one monthly treatment as flea larvae in the animal’s surroundings are killed

or prevented from developing to adults by treatment with REVOLUTION.

For the prevention and lasting control of flea infestations, REVOLUTION should be applied at

monthly intervals throughout the flea season, starting one month before fleas become active.

This ensures that fleas infesting the animal are killed and that no viable flea eggs are produced

by these fleas. Flea larvae in the animal’s surrounds are also killed by REVOLUTION. This

breaks the flea life cycle, controls and prevents flea infestations and improves the clinical signs

associated with flea allergy dermatitis in most animals. The clinical signs in some animals may

not respond to this treatment alone.

To obtain maximum flea control, it is recommended that all cats and dogs in the same

environment are treated.

Heartworm Prevention

For the prevention of heartworm disease REVOLUTION must be applied on a monthly basis.

REVOLUTION may be applied year-round or at least within one month after the animal’s first

exposure to mosquitoes and monthly thereafter until the end of the mosquito season. This dose

must be given within one month after the last exposure to mosquitoes. If a dose is missed and

a monthly interval between dosing is exceeded, then immediate application of REVOLUTION

and resumption of monthly dosing will minimise the opportunity for the development of adult

heartworms. When replacing another heartworm preventive product in a heartworm disease

prevention program, the first dose of REVOLUTION must be given within a month of the last

dose of the former medication.

REVOLUTION

safely

applied

heartworm

infected

animals,

however,

recommended, in accordance with good veterinary practice, that all animals

6 months of age

be tested for existing heartworm infections before beginning medication with REVOLUTION.

REVOLUTION is not effective against adult D. immitis; however it may decrease the number of

circulating microfilariae.

Ear Mite Treatment

A single dose of REVOLUTION was 100% effective in treating ear mites (O. cynotis) in

laboratory studies with dogs and cats. In field studies, with a potential for reinfestation, a single

dose of REVOLUTION eliminated ear mites in 100% of cats, and two monthly doses of

REVOLUTION eliminated ear mites in 90% of dogs. A single dose of REVOLUTION was also

found to be 100% effective in treating ear mites (Psoroptes cuniculi) in rabbits. Monthly use of

REVOLUTION in dogs and cats will treat any subsequent ear mite infestations. REVOLUTION

is suitable for a single treatment in rabbits. Cleansing of the infested ears is recommended to

remove the debris.

Sarcoptic Mange Treatment for Dogs and Rabbits

For the elimination of Sarcoptic mange (Sarcoptes scabiei), REVOLUTION should be applied

once and is highly efficacious as a single dose. A second monthly dose of REVOLUTION may

be required for complete elimination of mites in some dogs. Monthly use of REVOLUTION in

dogs will treat any subsequent Sarcoptes mite infestations. REVOLUTION is suitable for a

single treatment in rabbits.

Nematode Treatment for Cats

treatment

intestinal

hookworms

(A.

tubaeforme)

roundworms

(T.

cati),

REVOLUTION should be applied once as a single treatment. Monthly use of REVOLUTION will

control hookworm and roundworm infections.

Lice Treatment

A single dose of REVOLUTION was 100% effective in treating biting lice in dogs (Trichodectes

canis) and cats (Felicola subrostratus) with no lice found in laboratory studies at all

assessments between 7 and 42 days post treatment. A single dose of REVOLUTION eliminated

sucking lice (Linognathus setosus) in 90% of treated dogs when assessed 28 days after

treatment.

Cheyletiella Treatment for Rabbits

For the treatment of Cheyletiella mites (Cheyletiella sp.) in rabbits, a single dose of

REVOLUTION was effective at eliminating mites by 5 weeks post-treatment.

ANIMAL SAFETY:

DOGS: REVOLUTION has been tested with no adverse reactions in dogs of over 100 different

pure

mixed

breeds

including

Collies.

adverse

effects

were

observed

when

REVOLUTION was applied at 10 times the recommended dose and in pregnant and lactating

females, breeding males and females and dogs six weeks of age and older. REVOLUTION was

also applied at 3 times the recommended dose to heartworm infected dogs, and no adverse

effects were observed.

CATS: REVOLUTION has been tested with no serious adverse effects in cats of over 15

different pure and mixed breeds. No adverse effects were noted when REVOLUTION was

applied at 10 times the recommended dose and in pregnant and lactating females, breeding

males and females and cats six weeks of age and older. REVOLUTION was also applied at 4

times the recommended dose to heartworm infected cats, and no adverse effects were

observed. Accidental oral administration of REVOLUTION to cats may induce salivation or

vomiting.

RABBITS: REVOLUTION has been shown to be safe when applied at up to 3 times the

recommended dose. The safety of REVOLUTION has not been assessed following accidental

oral ingestion or in breeding rabbits of either sex including pregnant or lactating does.

Use of REVOLUTION in dogs and cats has occasionally been associated with transient

application site reactions such as alopoecia, coat colour change and pruritus. In well-controlled

clinical studies in dogs and cats, REVOLUTION was used safely in animals receiving other

frequently used veterinary products such as vaccines, anthelmintics, antiparasitics, antibiotics,

steroids, collars, shampoos and dips.

NOT TO BE USED FOR ANY PURPOSE, OR IN ANY MANNER, CONTRARY TO THIS LABEL

UNLESS AUTHORISED UNDER APPROPRIATE LEGISLATION

Presentation

REVOLUTION is available in tube sizes for dogs, cats and rabbits of different weights.

REVOLUTION for

Pack Colour

Contents (selamectin)

Puppies,

kittens

small

rabbits up to 2.5 kg

Mauve

1, 2, 3 or 15 x 15 mg

Cats, Rabbits: 2.6 – 7.5 kg

Blue

1, 2, 3 or 6 x 45 mg

Dogs: 2.6 – 5 kg

Purple

1, 2, 3 or 6 x 30 mg

Dogs: 5.1 – 10 kg

Brown

1, 2, 3 or 6 x 60 mg

Dogs: 10.1 – 20 kg

1, 2, 3 or 6 x 120 mg

Dogs: 20.1 – 40 kg

Teal

1, 2, 3 or 6 x 240 mg

Dogs above 40 kg and cats above 7.5 kg - use appropriate combination of tubes.

APVMA Approval Numbers: 50867/101622, 50881/101621, 50882/101619

Made in USA

Zoetis

Australia Pty Ltd

Level 6, 5 Rider Bvd

Rhodes NSW 2138

[This information is contained in a common leaflet for Revolution products 50867, 50881, 50882.]

Product Name: Revolution

Page: 1 of 7

This version issued: 21 May 2014

SAFETY DATA SHEET

Issued by: Zoetis Australia Pty Ltd

Phone: 1800 814 883

Poisons Information Centre: 13 1126 from anywhere in Australia

Section 1 - Identification of the Substance/Mixture and Supplier

Zoetis Australia Pty Ltd

ABN 94 156 476 425

38-42 Wharf Road

West Ryde NSW 2114 AUSTRALIA

Tel: 1800 814 883

Fax: (02) 8876 0444

Email: australia.animalhealth@zoetis.com

Product Identifier:

Revolution

APVMA Approval No:

50867, 50881, 50882

Other names:

Revolution for Puppies and Kittens; Revolution for Cats, Revolution for Dogs.

Chemical family:

Selamectin formulation

Recommended Use:

Topical Parasiticide for Dogs, Cats, Puppies, Kittens and Rabbits.

Restrictions on use

For veterinary use only.

Emergency Phone:

1800 814 883 (all hours)

Section 2 - Hazards Identification

Statement of Hazardous Nature

This product is classified as:

Xi, Irritating. N, Dangerous to the environment. F+, Highly Flammable. Hazardous

according to the criteria of SWA.

Dangerous according to the Australian Dangerous Goods (ADG) Code.

Risk Phrases:

R11, R36, R51. Highly flammable. Irritating to eyes. Toxic to aquatic organisms.

Safety Phrases:

S7, S16, S25, S26, S61. Keep container tightly closed. Keep away from heat, sparks, open flames

or other sources of ignition - No smoking. Avoid contact with eyes. In case of contact with eyes, rinse immediately

with plenty of water and contact a doctor or Poisons Information Centre. Avoid release to the environment. Refer to

special instructions/Safety Data Sheets.

ADG Classification:

Class 3: Flammable liquids.

GHS Label Elements:

Signal word: DANGER

GHS Classification:

H225: Highly flammable liquid and vapour.

H320: Causes eye irritation.

H401: Toxic to aquatic life.

PREVENTION

P102: Keep out of reach of children.

P210: Keep away from heat, sparks, open flames and hot surfaces. - No smoking.

P233: Keep container tightly closed.

P262: Do not get in eyes.

P264: Wash contacted areas thoroughly after handling.

P273: Avoid release to the environment.

P281: Use personal protective equipment as required.

RESPONSE

P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353: IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse skin with water.

P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if

present and easy to do. Continue rinsing.

P337+P313: If eye irritation persists: Get medical advice.

P370+P378: In case of fire, use carbon dioxide, dry chemical, foam, water fog. Alcohol resistant foam is the

preferred firefighting medium but, if it is not available, fine water spray can be used.

Product Name: Revolution

Page: 2 of 7

This version issued: 21 May 2014

SAFETY DATA SHEET

Issued by: Zoetis Australia Pty Ltd

Phone: 1800 814 883

Poisons Information Centre: 13 1126 from anywhere in Australia

STORAGE

P410: Protect from sunlight.

P402+P404: Store in a dry place. Store in a closed container.

P403+P235: Store in a well-ventilated place. Keep cool.

DISPOSAL

P501: Dispose of small quantities and empty containers by wrapping with paper and putting in garbage. For

larger quantities, if recycling or reclaiming is not possible, use a commercial waste disposal service.

Other/supplementary hazards. None known.

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Physical Description & colour

: Colourless to pale yellow solution.

Odour:

Characteristic odour of isopropanol.

Major Health Hazards:

eye irritant.

No specific medical attention is advised. Treat symptomatically.

Section 3 - Composition/Information on Ingredients

Ingredients

CAS No

Conc,%

TWA (mg/m

STEL (mg/m

Selamectin

165108-07-6

60mg/mL

not set

not set

Isopropanol

67-63-0

600-800mg/mL

1230

Other non hazardous ingredients

secret

to 100

not set

not set

This is a commercial product whose exact ratio of components may vary slightly. Minor quantities of other non

hazardous ingredients are also possible.

The SWA TWA exposure value is the average airborne concentration of a particular substance when calculated over a normal 8 hour working day

for a 5 day working week. The STEL (Short Term Exposure Limit) is an exposure value that may be equalled (but should not be exceeded) for no

longer than 15 minutes and should not be repeated more than 4 times per day. There should be at least 60 minutes between successive exposures

at the STEL. The term "peak "is used when the TWA limit, because of the rapid action of the substance, should never be exceeded, even briefly.

Section 4 - First Aid Measures

General Information:

You should call The Poisons Information Centre if you feel that you may have been poisoned, burned or irritated by

this product. The number is 13 1126 from anywhere in Australia and is available at all times. Have this SDS with you

when you call.

Inhalation:

First aid is not generally required. If in doubt, contact a Poisons Information Centre or a doctor.

Skin Contact:

Wash gently and thoroughly with water (use non-abrasive soap if necessary) for 5 minutes or until

chemical is removed.

Eye Contact:

Immediately flush the contaminated eye(s) with lukewarm, gently flowing water for 20 minutes or until

the product is removed, while holding the eyelid(s) open. Take care not to rinse contaminated water into the

unaffected eye or onto the face. Obtain medical attention immediately. Take special care if exposed person is wearing

contact lenses.

Ingestion:

If product is swallowed or gets in mouth, do NOT induce vomiting; wash mouth with water and give some

water to drink. If symptoms develop, or if in doubt contact a Poisons Information Centre or a doctor.

Most Important Symptoms and Effects, Both Acute and Delayed: None known.

Symptoms and Effects of Exposure: None known.

Medical Conditions Aggravated by Exposure: None known.

Indication of the Immediate Medical Attention and Special Treatment Needed: None known.

Notes to Physician: None.

Section 5 - Fire Fighting Measures

Hazards arising from the product

: The major hazard in fires is usually inhalation of heated and toxic or oxygen

deficient (or both), fire gases. There is a moderate risk of an explosion from this product if commercial quantities are

involved in a fire. Firefighters should take care and appropriate precautions. Any explosion will likely spread the fire to

surrounding materials. Water spray may be used to cool packages involved in a fire, reducing the chances of an

explosion. Vapours from this product are heavier than air and may accumulate in sumps, pits and other low-lying

spaces, forming potentially explosive mixtures. They may also flash back considerable distances.

Fire decomposition products from this product may be toxic if inhaled. Take appropriate protective measures.

Product Name: Revolution

Page: 3 of 7

This version issued: 21 May 2014

SAFETY DATA SHEET

Issued by: Zoetis Australia Pty Ltd

Phone: 1800 814 883

Poisons Information Centre: 13 1126 from anywhere in Australia

Suitable Extinguishing Media

: In case of fire, use carbon dioxide, dry chemical, foam, water fog. Alcohol

resistant foam is the preferred firefighting medium but, if it is not available, fine water spray can be used. Try to

contain spills, minimise spillage entering drains or water courses.

Special Protective Equipment and Precautions for Firefighters

: If a significant quantity of this product is

involved in a fire, call the fire brigade. There is a danger of a violent reaction or explosion if significant quantities of

this product are involved in a fire. Recommended personal protective equipment is full fire kit and breathing

apparatus.

Hazchem Code:

2YE

Section 6 - Accidental Release Measures

Personal precautions, protective equipment and emergency procedures:

This product is sold in small

packages, and the accidental release from one of these is not usually a cause for concern. For minor spills, clean up,

rinsing to sewer and put empty container in garbage. Although no special protective clothing is normally necessary

because of occasional minor contact with this product, it is good practice to wear impermeable gloves when handling

chemical products. In the event of a major spill, prevent spillage from entering drains or water courses and call

emergency services.

Environmental Precautions: None.

Methods and Material for Containment and Cleaning Up. This product is sold in small packages. No special

measures are usually necessary following spills.

Measures for Cleaning / Collecting: Contain the source of the spill if it is safe to do so. Absorb spills with non-

combustible absorbent material and transfer into a labelled container for disposal.

Additional Consideration for Large Spills: Non-essential personnel should be evacuated from affected area.

Report emergency situations immediately. Clean up operations should only be undertaken by trained personnel.

Section 7 - Handling and Storage

Handling

: Keep exposure to this product to a minimum, and minimise the quantities kept in work areas. Check

Section 8 of this SDS for details of personal protective measures, and make sure that those measures are followed.

The measures detailed below under "Storage" should be followed during handling in order to minimise risks to

persons using the product in the workplace. Also, avoid contact or contamination of product with incompatible

materials listed in Section 10.

Storage

: Store in a cool, well ventilated area, and make sure that surrounding electrical devices and switches are

suitable. Check containers periodically for leaks. Containers should be kept closed in order to minimise contamination

and possible evaporation. Make sure that the product does not come into contact with substances listed under

"Incompatibilities" in Section 10. If you keep more than 2500kg or L of Dangerous Goods of Packaging Group II, you

may be required to license the premises or notify your Dangerous Goods authority. If you have any doubts, we

suggest you contact your Dangerous Goods authority in order to clarify your obligations. Check packaging - there may

be further storage instructions on the label.

Section 8 - Exposure Controls and Personal Protection

Control Parameters:

The following Australian Standards will provide general advice regarding safety clothing and equipment:

Respiratory equipment: AS/NZS 1715, Protective Gloves: AS 2161, Occupational Protective Clothing: AS/NZS 4501

set 2008, Industrial Eye Protection: AS1336 and AS/NZS 1337, Occupational Protective Footwear: AS/NZS2210.

SWA Exposure limits

TWA (mg/m

3

)

STEL (mg/m

3

)

Isopropanol

1230

Engineering Controls:

No special equipment is usually needed when occasionally handling small quantities. The

following instructions are for bulk handling or where regular exposure in an occupational setting occurs without proper

containment systems.

This product should only be used in a well ventilated area. If natural ventilation is inadequate, use of a fan is

suggested.

Eye Protection:

Protective glasses or goggles should be worn when this product is being used. Failure

to protect your eyes may cause them harm. Emergency eye wash facilities are also recommended in an area close to

where this product is being used.

Skin Protection:

You should avoid contact even with mild skin irritants. Therefore you should wear suitable

impervious elbow-length gloves and facial protection when handling this product. See below for suitable material

types.

Protective Material Types:

We suggest that protective clothing be made from the following materials: Viton,

nitrile.

Product Name: Revolution

Page: 4 of 7

This version issued: 21 May 2014

SAFETY DATA SHEET

Issued by: Zoetis Australia Pty Ltd

Phone: 1800 814 883

Poisons Information Centre: 13 1126 from anywhere in Australia

Respirator:

Usually, no respirator is necessary when using this product. However, if you have any doubts consult

the Australian Standard mentioned above.

Eyebaths or eyewash stations should, if practical, be provided near to where this product is being handled

commercially.

Section 9 - Physical and Chemical Properties:

Appearance

Colourless to pale yellow solution.

Odour:

Characteristic odour of isopropanol.

Odour Threshold:

No data.

pH:

No data.

Freezing/Melting Point:

No specific data. Liquid at normal temperatures.

Boiling Point:

84°C at 100kPa

Flash point

:

19°C

Upper Flammability Limit:

No data.

Lower Flammability Limit:

No data.

Autoignition temperature:

No data.

Flammability Class:

Flammable Category 2 (GHS); Highly Flammable (AS1940).

Upper Flammability Limit:

No data.

Lower Flammability Limit:

No data.

Autoignition temperature:

No data.

Flammability (solid, gas):

Not applicable.

Decomposition Temperature:

No data.

Volatiles:

Isopropanol content.

Vapour Pressure:

No data.

Vapour Density:

No data.

Relative Density:

0.815-0.847

Water Solubility:

Soluble.

Solvent Solubility:

No data.

Volatility:

No data.

Evaporation Rate:

No data.

Partition Coefficient (n-octanol/water)

No data

Autoignition temp:

No data.

Viscosity:

Not applicable.

Section 10 - Stability and Reactivity

Reactivity:

This product is unlikely to react or decompose under normal storage conditions. However, if you have

any doubts, contact the supplier for advice on shelf life properties.

Stability:

Stable if stored under normal conditions.

Conditions to Avoid:

This product should be kept in a cool place, preferably below 30°C. Protect this product from

light. Store in the closed original container in a dry, cool, well-ventilated area out of direct sunlight.

Incompatibilities:

strong oxidising agents.

Hazardous decomposition products:

Combustion forms carbon dioxide, and if incomplete, carbon monoxide

and possibly smoke. Water is also formed. Carbon monoxide poisoning produces headache, weakness, nausea,

dizziness, confusion, dimness of vision, disturbance of judgment, and unconsciousness followed by coma and death.

Polymerisation:

This product will not undergo polymerisation reactions.

Section 11 - Toxicological Information

S

S

S

y

y

y

m

m

m

p

p

p

t

t

t

o

o

o

m

m

m

s

s

s

c

c

c

a

a

a

u

u

u

s

s

s

e

e

e

d

d

d

b

b

b

y

y

y

E

E

E

x

x

x

p

p

p

o

o

o

s

s

s

u

u

u

r

r

r

e

e

e

General Information:

No data.

Product Name: Revolution

Page: 5 of 7

This version issued: 21 May 2014

SAFETY DATA SHEET

Issued by: Zoetis Australia Pty Ltd

Phone: 1800 814 883

Poisons Information Centre: 13 1126 from anywhere in Australia

Routes of exposure:

No data.

Symptoms of exposure:

No data.

Inhalation:

Short term exposure:

Available data indicates that this product is not harmful. In addition product is unlikely to

cause any discomfort or irritation.

Long Term exposure:

No data for health effects associated with long term inhalation.

Skin Contact:

Short term exposure:

Available data indicates that this product is not harmful. It should present no hazards in

normal use. However product may be irritating, but is unlikely to cause anything more than mild transient discomfort.

Long Term exposure:

No data for health effects associated with long term skin exposure.

Eye Contact:

Short term exposure

: This product is an eye irritant. Symptoms may include stinging and reddening of eyes and

watering which may become copious. Other symptoms may also become evident. If exposure is brief, symptoms

should disappear once exposure has ceased. However, lengthy exposure or delayed treatment may cause permanent

damage.

Long Term exposure

: No data for health effects associated with long term eye exposure.

Ingestion:

Short term exposure

: Significant oral exposure is considered to be unlikely. However, this product may be

irritating to mucous membranes but is unlikely to cause anything more than transient discomfort.

Long Term exposure

: No data for health effects associated with long term ingestion.

Specific Target Organ Toxicity (STOT) – single exposure:

No data.

Specific Target Organ Toxicity (STOT) – repeated exposure:

No data.

Aspiration Hazard:

No data.

Early Onset Symptoms Related to Exposure:

No data.

Delayed Health Effects from Exposure:

No data.

Exposure Levels and Health Effects:

No data.

Interactive Effects:

No data.

C

C

C

l

l

l

a

a

a

s

s

s

s

s

s

i

i

i

f

f

f

i

i

i

c

c

c

a

a

a

t

t

t

i

i

i

o

o

o

n

n

n

o

o

o

f

f

f

H

H

H

a

a

a

z

z

z

a

a

a

r

r

r

d

d

d

o

o

o

u

u

u

s

s

s

I

I

I

n

n

n

g

g

g

r

r

r

e

e

e

d

d

d

i

i

i

e

e

e

n

n

n

t

t

t

s

s

s

Ingredient

Risk Phrases

Isopropanol

Conc>=20%: Xi; R36

Selamectin:

Oral, Rat >1600mg/kg

Oral, Mouse = >1600mg/kg

Isopropanol:

Oral, Rat >2000mg/kg

Oral, Mouse = 3600mg/kg

Dermal, Rabbit = 12800mg/kg

Inhalation, Rat = 16mg/L/4hr

Repeated Dose Toxicity:

(Duration,

Species,

Route,

Dose,

End Point,

Target Organ)

Isopropyl alcohol

20 Week(s)

Inhalation 4000 ppm

NOAEL Liver, Central nervous system

104 Week(s)

Inhalation 5000 ppm

Kidney

Selamectin

3 Month(s)

Oral

5 mg/kg/day

NOAEL

Liver

3 Month(s)

Oral

40 mg/kg/day

NOAEL

None identified

Reproduction & Developmental Toxicity:

(Study Type,

Species,

Route,

Dose,

End Point,

Effect(s))

Reproductive & Fertility

10 mg/kg/day

NOAEL

Foetotoxicity

Prenatal & Postnatal Development Rat

10 mg/kg/day

NOAEL

Developmental toxicity

Prenatal & Postnatal Development Rat

Oral

40 mg/kg/day

NOAEL

Maternal Toxicity

Bacterial Mutagenicity (Ames) Salmonella Negative

In Vitro Cytogenetics Human Lymphocytes Negative

Mammalian Cell Mutagenicity Chinese Hamster Ovary (CHO) cells HGPRT Negative

Prenatal & Postnatal Development Rat Oral 40 mg/kg/day NOAEL Maternal Toxicity

There is no data to hand indicating any particular target organs.

Respiratory or Skin Sensitisation:

No data.

Germ Cell Mutagenicity:

No data.

Carcinogenicity:

No data.

Reproductive Toxicity:

No data.

Product Name: Revolution

Page: 6 of 7

This version issued: 21 May 2014

SAFETY DATA SHEET

Issued by: Zoetis Australia Pty Ltd

Phone: 1800 814 883

Poisons Information Centre: 13 1126 from anywhere in Australia

Carcinogen Status:

SWA:

No significant ingredient is classified as carcinogenic by SWA.

NTP:

No significant ingredient is classified as carcinogenic by NTP.

IARC:

Isopropanol is Class 3 - unclassifiable as to carcinogenicity to humans.

See the IARC website for further details. A web address has not been provided as addresses frequently change.

Section 12 - Ecological Information

This product is toxic to aquatic organisms. This product is biodegradable. It will not accumulate in the soil or water or

cause long term problems.

Aquatic Toxicity, Selamectin:

(Species,

Method,

End Point, Duration,

Result)

Daphnia magna (Water Flea)

OECD

EC50

48 Hours

26 ng/L

Mysidopsis bahia (Mysid Shrimp)

LC50

96 Hours

28 ng/L

Cyprinodon variegatus (Sheepshead Minnow)

LC50

48 Hours

> 500 µg/L

Selenastrum capricornutum (Green Alga)

OECD

EC50

72 Hours

>763 µg//L

Oncorhynchus mykiss (Rainbow Trout)

OECD

LC50

96 Hours

266 µg/L

Toxicity information:

No data.

Persistence and degradability:

No data.

Bioaccumulative potential:

No data.

Mobility in soil:

No data.

Other adverse effects:

No data.

Section 13 - Disposal Considerations

Disposal:

Dispose of small quantities and empty containers by wrapping with paper and putting in garbage. For

larger quantities, if recycling or reclaiming is not possible, use a commercial waste disposal service.

Section 14 - Transport Information

UN Number:

1219

Proper Shipping name:

ISOPROPANOL

Transport Class or Division:

Packing Group:

Limited quantities:

ADG 7 specifies a Limited Quantity value of 1 L for this class of product.

Dangerous Goods Class:

Class 3: Flammable liquids.

Class 3 Flammable Liquids shall not be loaded in the same vehicle or packed in the same freight container with

Classes 1 (Explosives), 2.1 (Flammable Gases where flammable liquids and flammable gases are both in bulk), 2.3

(Toxic Gases), 4.2 (Spontaneously Combustible Substances), 5.1 (Oxidising Agents), 5.2 (Organic Peroxides), 6

(Toxic Substances, except Flammable Liquid is nitromethane), and 7 (Radioactive Substances). They may however

be loaded in the same vehicle or packed in the same freight container with Classes 2.1 (Flammable Gases except

where the Flammable Liquids and Flammable Gases are in bulk), 2.2 (Non-Flammable Non-Toxic Gases), 4.1

(Flammable Solids), 4.3 (Dangerous When Wet Substances), 6 (Toxic Substances, where Flammable Liquid is

nitromethane), 8 (Corrosive Substances), 9 (Miscellaneous Dangerous Goods), Foodstuffs or foodstuff empties.

Hazchem Code:

2YE

Special precaution for user:

None known.

Additional Information:

None known.

Environmental Hazard:

This product is classed as environmentally hazardous. Take appropriate precautions

when transporting, handling or cleaning up spills.

Section 15 - Regulatory Information

Poison Schedule:

None allocated.

AICS:

All of the significant ingredients in this formulation are compliant with NICNAS regulations.

The following ingredient: Selamectin, is mentioned in the SUSMP.

Product Name: Revolution

Page: 7 of 7

This version issued: 21 May 2014

SAFETY DATA SHEET

Issued by: Zoetis Australia Pty Ltd

Phone: 1800 814 883

Poisons Information Centre: 13 1126 from anywhere in Australia

Section 16 - Other Information

This SDS contains only safety-related information. For other data see product literature.

Data Sources:

The data contained in this SDS may have been gathered from confidential internal sources, raw

material suppliers, or from the published literature.

Acronyms:

ADG Code

Australian Code for the Transport of Dangerous Goods by Road and Rail (7

edition)

AICS

Australian Inventory of Chemical Substances

SWA

Safe Work Australia, formerly ASCC and NOHSC

CAS number

Chemical Abstracts Service Registry Number

Hazchem Code

Emergency action code of numbers and letters that provide information to emergency

services especially firefighters

IARC

International Agency for Research on Cancer

NOS

Not otherwise specified

NTP

National Toxicology Program (USA)

R-Phrase

Risk Phrase

SUSMP

Standard for the Uniform Scheduling of Medicines & Poisons

UN Number

United Nations Number

This version issued: 21 May 2014

and is valid for 5 years from this date.

Supercedes

Revision History:

Date of Revision

Reason

Contact Points:

Zoetis

1800 814 883

Police and Fire Brigade:

Dial 000

If ineffective:

Dial Poisons Information Centre

(13 1126 from anywhere in Australia)

THIS SDS SUMMARISES OUR CURRENT AND BEST KNOWLEDGE OF THE HEALTH AND SAFETY HAZARD

INFORMATION ABOUT THE PRODUCT DETAILED IN THIS SDS, AND HOW TO SAFELY HANDLE AND USE

THE PRODUCT IN THE WORKPLACE FOR THE RECOMMENDED USE. EACH USER OF THE PRODUCT MUST

REVIEW THIS SDS IN THE CONTEXT OF HOW THE PRODUCT WILL BE HANDLED AND USED IN THEIR OWN

WORKPLACE. IF CLARIFICATION OR FURTHER INFORMATION IS NEEDED TO ENSURE THAT AN

APPROPRIATE RISK ASSESSMENT CAN BE MADE, THE USER SHOULD CONTACT ZOETIS.

Please read all labels carefully before using product.

This SDS is prepared in accord with the SWA document “Preparation of Safety Data Sheets for Hazardous

Chemicals - Code of Practice” (December 2011)

© 2014 Zoetis Inc, All rights reserved.

Prepared by Kilford & Kilford Pty Ltd

End of Safety Data Sheet

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