MULTINE SELENISED

New Zealand - English - Ministry for Primary Industries

Active ingredient:
clostridium tetani toxoid; sodium selenate; clostridium perfringens type d toxoid; clostridium novyi type b toxoid/cells; clostridium septicum toxoid; clostridium chauvoei toxoid/cells
Available from:
Schering-Plough Animal Health Ltd
INN (International Name):
clostridium septicum toxoid, clostridium tetani toxoid, clostridium perfringens type d toxoid, sodium selenate, clostridium chau
Composition:
clostridium tetani toxoid 0 vaccine; sodium selenate 6 g/litre; clostridium perfringens type d toxoid 0 vaccine; clostridium novyi type b toxoid/cells 0 vaccine; clostridium septicum toxoid 0 vaccine; clostridium chauvoei toxoid/cells 0 vaccine
Therapeutic area:
Vaccine
Authorization status:
ACVM Registered
Authorization number:
A000935
Authorization date:
1968-11-20

Read the complete document

Read the complete document

MULTINE SELENISED

250 mL and 500 mL – Leaflet, Carton and Label

A000935

Page 1 of 10

MULTINE SELENISED

31-Mar-2021

Leaflet

WARNING

Keep out of reach of children

FOR ANIMAL TREATMENT ONLY

MULTINE

®

SELENISED

5-in-1 Clostridial Vaccine

plus Selenium

Each 2 mL provides 5 mg of Selenium.

500 mL (250 doses)

[250 mL (125 doses)]

Read entire leaflet before use.

MULTINE SELENISED contains toxoids of Clostridium perfringens (type D), C. septicum, C.

tetani; anacultures of C. novyi (type B), C. chauvoei; plus 2.5 mg/mL of Selenium (as

sodium selenate).

MULTINE SELENISED also contains potash alum adjuvant and 0.015% w/v thiomersal.

INDICATIONS

MULTINE SELENISED provides protection to sheep and goats for the following clostridial

diseases: Pulpy Kidney, Tetanus, Blackleg, Black Disease and Malignant Oedema.

Selenium can treat and prevent selenium responsive diseases such as white muscle

disease, infertility, depressed growth rates and wool production.

PRECAUTIONS

NOT FOR USE IN LAMBS AT DOCKING/TAILING.

MULTINE SELENISED should only be used when there is a known requirement for

selenium i.e. there has been a veterinary diagnosis of selenium deficiency.

Do not use at the same time as any other selenised fertiliser, prill or product and do not

exceed the stated dose or frequency without consulting a veterinarian.

MULTINE SELENISED is not registered for use in cattle. The amount of selenium used

in this product is appropriate for sheep.

EQUIPMENT

Use sharp needles.

Change needles frequently (every 12 to 20 sheep).

Needles and vaccinator guns should be sterile before starting. Needles can be sterilised

by boiling for 10 minutes and storing in methylated spirits.

ASSEMBLY OF VAXIPAK

®

AND DRAW-OFF SET

1. Attach end of draw-off tube to the vaccinator gun.

2. Pierce centre of rubber stopper of Vaxipak with draw-off needle, ensuring that plastic

overcap snaps into position on the Vaxipak cap.

3. Plastic cord is provided for hanging MULTINE SELENISED in a convenient position e.g.

from neck, belt, rail.

DIRECTIONS FOR USE

MULTINE SELENISED

250 mL and 500 mL – Leaflet, Carton and Label

A000935

Page 2 of 10

MULTINE SELENISED

31-Mar-2021

By law the user must take due care, obtaining expert advice when necessary, to avoid

unnecessary pain and distress when using the product other than as directed on the

label.

VACCINATION

Shake well before use.

Ensure vaccinator gun delivers correct dose.

Vaccinate only clean, dry animals.

Inject in the anterior (front) half of the neck.

Inject subcutaneously i.e. between the skin and muscle.

Part the wool, raise the skin to form a “tent” and insert the needle into the “tent opening”

so that the needle is almost parallel with the neck.

DOSE

Sheep and goats: 2 mL.

VACCINATION PROGRAMME

The choice of vaccine and programme depends on timing of disease risk, age and class of

animal. The following programmes can be used as a guide:

Sensitiser

Booster

Notes

Use of other

Multine products

Lambs

Weaning or

from 12

weeks

4-6 weeks

after

sensitiser

Animals not fully

protected until

after booster

vaccination

Any other Multine

product [MULTINE

(A000934),

MULTINE B12

(A011311) or

MULTINE B12

SELENISED

(A011766)] can be

used as a booster.

Animals

with

unknown

vaccination

history

As soon as

possible

4-6 weeks

after

sensitiser

Animals not fully

protected until

after booster

vaccination

Previously

vaccinated

animals

required

Annual

Best done prior to

lambing to provide

protection for

suckling offspring;

or prior to periods

of high risk

As with all vaccines, efficacy is based on the immune response of animals to vaccination.

The level of exposure to challenge, management issues and health status of animal affects

the level of protection from disease.

SHEEP VACCINATION PROGRAMME

Initial vaccination programme

To protect lambs at weaning, hoggets and adult sheep against clostridial disease.

MULTINE SELENISED

250 mL and 500 mL – Leaflet, Carton and Label

A000935

Page 3 of 10

MULTINE SELENISED

31-Mar-2021

Unvaccinated sheep (including lambs from weaning) must be given 2 injections, a

sensitiser and booster at least 4-6 weeks apart.*

Thereafter, sheep should be boosted annually.

Lambs and sheep should be fully vaccinated (sensitiser and booster) at least 2 weeks

prior to periods of risk.

Use MULTINE or NILVAX for hoggets, ewes; and MULTINE for lambs.

*Note

The interval between the sensitiser and booster should be at least 4 weeks and can be

longer, e.g. new breeding ewes can be sensitised at tupping and boosted just before

lambing to give good lamb colostral immunity and good ewe protection over the high-risk

lambing period. The ewe herself will not be fully protected until after the booster has been

given. Ensure the booster is completed at least 2 weeks before the anticipated risk period.

Contact your animal health advisor for more information.

Vaccination of the pregnant ewe

Ewes which have been previously vaccinated are boosted:

- 2 to 4 weeks before lambing with either MULTINE SELENISED, MULTINE (A000934),

MULTINE B12 (A011311) or MULTINE B12 SELENISED (A011766)

- 2 to 6 weeks before lambing with NILVAX

®

SELENISED (A003977),

to give optimum lamb protection via colostrum. This also boosts the ewe prior to

lambing, a period of high risk for ewes.

Colostral immunity from ewes vaccinated with MULTINE SELENISED usually provides

protection to the lamb for up to 3 months and NILVAX SELENISED (A003977) up to 4

months.**

Lambs born to ewes which were vaccinated in late pregnancy receive immunity via the

colostrum.

Lambs absorb this immunity in the first day of life; therefore, it is important they suckle as

soon as possible.

**Note

The degree of protection passed to lambs from the ewe will vary depending on the ewe’s

level of immunity and the amount of colostrum absorbed by the lamb. These factors are, in

turn, affected by the time since ewe vaccination, the lamb’s ability to suckle, suckling

frequency, and number of lambs being suckled. Therefore, within a flock there may be

varying time periods of protection.

If the ewe has not been fully vaccinated pre-lamb

For immediate and short-term (2 to 3 weeks) protection lambs should be given LAMB

VACCINE (A001009) or LAMB VACCINE SELENISED (A001011) at docking/tailing. This

provides Tetanus protection as well as providing a Pulpy Kidney sensitiser.

GOAT VACCINATION PROGRAMME

MULTINE SELENISED can be used to protect against all 5 diseases in the same way as

MULTINE SELENISED is used in sheep. However, it is advisable to seek veterinary advice

before starting a programme for goats.

ADVERSE EFFECTS

As with any vaccine, hypersensitivity reactions may occur in animals following vaccination.

Immediate treatment with adrenaline (epinephrine) is recommended. Antihistamines and

corticosteroids may also be useful.

WITHHOLDING PERIODS

Nil.

MULTINE SELENISED

250 mL and 500 mL – Leaflet, Carton and Label

A000935

Page 4 of 10

MULTINE SELENISED

31-Mar-2021

WARNING

HANDLING PRECAUTIONS: May be harmful if swallowed. Causes mild skin irritation.

Contains thiomersal (0.015%) which may cause an allergic skin reaction. Suspected of

causing cancer by repeated oral exposure. Do not handle until all safety instructions have

been read and understood. Wear protective gloves and clothing. Avoid skin contact. Wash

hands and exposed skin after handling. Take off contaminated clothing and wash before

reuse.

FIRST AID: If on skin wash with plenty of soap and water. If swallowed and you feel

unwell or if skin irritation/rash occurs seek medical advice - National Poisons Centre 0800

POISON (0800 764 766) or a doctor.

ACCIDENTAL SELF-INJECTION: Obtain medical attention - show this leaflet and/or

SDS. Accidental self-injection may lead to an inflammatory response and medical advice

should be sought on the management of deep injections, particularly those near a joint or

associated with bruising. If possible, the application of gentle squeezing pressure with

absorbent material (e.g. facial tissues) at the injection site will swab up unabsorbed

vaccine. Strong squeezing of the site should be avoided. The damaged area should be

thoroughly cleansed, and a topical antiseptic applied.

ADVICE TO DOCTOR: Treat symptomatically. Some risk of hypersensitivity from

injection. Contains safety tested inactivated bacterial toxins. Contamination of the needle

must be considered.

ENVIRONMENTAL HAZARDS: Harmful to aquatic life with long lasting effects. Harmful to

the terrestrial environment with long lasting effects. Avoid unintended release into the

environment.

DISPOSAL: Dispose of unused contents in a suitable landfill. Dispose of empty Vaxipak

by puncturing and burying in a suitable landfill. Do NOT burn.

See safety data sheet (SDS) for further information: www.msd-animal-health.co.nz

STORAGE

Store away from light at 2°C to 8°C. DO NOT FREEZE. Store locked up.

A partially used pack can be kept for use for up to 6 weeks if the following steps are taken:

1. Carefully remove the draw-off tube from the rubber stopper.

2. Empty the draw-off tube and vaccinator by depressing the plunger several times.

3. Remove the draw-off tube from the vaccinator gun.

4. Disinfect the stopper by wiping it with a clean cloth soaked in methylated spirits.

5. Store the vaccine in its original cardboard carton and place upright in the refrigerator (2°C

to 8°C). DO NOT FREEZE. Store locked up.

6. Re-use with sterile needles, vaccinator gun and draw-off tube.

Registered pursuant to the ACVM Act 1997, No. A000935.

See www.foodsafety.govt.nz for registration conditions.

Approved pursuant to the HSNO Act 1996, HSR000015.

See www.epa.govt.nz for approval conditions.

Registered to

Schering-Plough Animal Health Ltd

33 Whakatiki Street,

Upper Hutt 5018

Phone: 0800 800 543

www.msd-animal-health.co.nz

MULTINE SELENISED

250 mL and 500 mL – Leaflet, Carton and Label

A000935

Page 5 of 10

MULTINE SELENISED

31-Mar-2021

® Registered trademark

© Copyright [Year]

MADE FOR NEW ZEALAND, IN NEW ZEALAND

MSD AH logo

MULTINE SELENISED

250 mL and 500 mL – Leaflet, Carton and Label

A000935

Page 6 of 10

MULTINE SELENISED

31-Mar-2021

Carton – Front panel

WARNING

Keep out of reach of children

FOR ANIMAL TREATMENT ONLY

MULTINE

®

SELENISED

5-in-1 Clostridial Vaccine

plus Selenium

Provides protection against Pulpy Kidney, Tetanus, Blackleg, Black Disease and Malignant

Oedema in sheep and goats.

Each 2 mL provides 5 mg of Selenium.

125 doses

2 mL per dose

[250 doses]

250 mL

[500 mL]

MSD AH logo

Carton – Side panel 1

MULTINE

®

SELENISED

5-IN-1 VACCINE

250 mL (125 doses)

[500 mL (250 doses)]

Carton – Side panel 2

MULTINE

®

SELENISED

5-IN-1 VACCINE

250 mL (125 doses)

[500 mL (250 doses)]

Batch No.

Expiry

MULTINE SELENISED

250 mL and 500 mL – Leaflet, Carton and Label

A000935

Page 7 of 10

MULTINE SELENISED

31-Mar-2021

Carton – Back panel

MULTINE

®

SELENISED

5-IN-1 VACCINE

Read entire leaflet before use.

MULTINE SELENISED contains toxoids of Clostridium perfringens (type D), C. septicum, C.

tetani; anacultures of C. novyi (type B) and C. chauvoei; plus 2.5 mg/mL of Selenium (as

sodium selenate).

Selenium can treat and prevent selenium responsive diseases such as white muscle

disease, infertility, depressed growth rates and wool production.

VACCINATION PROGRAMME

Sensitiser

Booster

Notes

Use of other

Multine products

Lambs

Weaning or

from 12

weeks

4-6 weeks

after

sensitiser

Animals not fully

protected until

after booster

vaccination

Any other Multine

product [MULTINE

(A000934),

MULTINE B12

(A011311) or

MULTINE B12

SELENISED

(A011766)] can be

used as a booster

Animals

with

unknown

vaccination

history

As soon as

possible

4-6 weeks

after

sensitiser

Animals not fully

protected until

after booster

vaccination

Previously

vaccinated

animals

Not required

Annual

Best done just

prior to lambing to

provide protection

for suckling

offspring; or prior

to periods of high

risk

DOSE: Sheep and goats: 2 mL.

Vaccinate subcutaneously in the anterior (front) half of the neck.

PRECAUTIONS

NOT FOR USE IN LAMBS AT DOCKING/TAILING.

MULTINE SELENISED should only be used when there is a known requirement

for selenium i.e. there has been a veterinary diagnosis of selenium deficiency.

Do not use at the same time as any other selenised fertiliser, prill or product and do

not exceed the stated dose or frequency without consulting a veterinarian.

MULTINE SELENISED is not registered for use in cattle. The amount of selenium used

in this product is appropriate for sheep.

WITHHOLDING PERIODS: Nil.

MULTINE SELENISED

250 mL and 500 mL – Leaflet, Carton and Label

A000935

Page 8 of 10

MULTINE SELENISED

31-Mar-2021

WARNING

HANDLING PRECAUTIONS: May be harmful if swallowed. Causes mild skin

irritation. Contains thiomersal (0.015%) which may cause an allergic skin reaction.

Suspected of causing cancer by repeated oral exposure. Do not handle until all

safety instructions have been read and understood. Wear protective gloves and

clothing. Avoid skin contact. Wash hands and exposed skin after handling. Take off

contaminated clothing and wash before reuse.

FIRST AID: If on skin wash with plenty of soap and water. If swallowed and you

feel unwell or if skin irritation/rash occurs seek medical advice - National Poisons

Centre 0800 POISON (0800 764 766) or a doctor.

ACCIDENTAL SELF-INJECTION: Obtain medical attention. See leaflet for advice.

DISPOSAL: Dispose of unused contents in a suitable landfill. Dispose of empty

vaxipak by puncturing and burying in a suitable landfill. Do NOT burn.

See safety data sheet (SDS) for further information: www.msd-animal-health.co.nz

STORAGE: Store away from light at 2°C to 8°C. DO NOT FREEZE. Store locked up.

Unused vaccine can be stored for up to 6 weeks after opening (see leaflet for storage

conditions).

Registered pursuant to the ACVM Act 1997, No. A000935.

See www.foodsafety.govt.nz for registration conditions.

Approved pursuant to HSNO Act 1996, HSR000015.

See www.epa.govt.nz for approval conditions.

MULTINE SELENISED

250 mL and 500 mL – Leaflet, Carton and Label

A000935

Page 9 of 10

MULTINE SELENISED

31-Mar-2021

Carton – Top panel

MULTINE

®

SELENISED

5-IN-1 VACCINE

250 mL (125 doses)

[500 mL (250 doses)]

Registered to

Schering-Plough Animal Health Ltd

Phone: 0800 800 543

www.msd-animal-health.co.nz

® Registered trademark

© Copyright [Year]

MSD AH logo

Carton – Bottom panel

MADE FOR NEW ZEALAND, IN NEW ZEALAND

Barcode

MULTINE SELENISED

250 mL and 500 mL – Leaflet, Carton and Label

A000935

Page 10 of 10

MULTINE SELENISED

31-Mar-2021

Label

WARNING

Keep out of reach of children

FOR ANIMAL TREATMENT ONLY

MULTINE

®

SELENISED

5-in-1 Clostridial Vaccine

plus Selenium

Read entire leaflet before use. Shake well before use.

DOSE: Sheep and goats: 2 mL.

Vaccinate subcutaneously in the anterior (front) half of the neck.

NOT FOR USE IN LAMBS AT DOCKING/TAILING. Only for use in selenium deficient

animals.

STORAGE: Store away from light at 2°C to 8°C. DO NOT FREEZE. Store locked up.

Unused vaccine can be stored for up to 6 weeks after opening (see leaflet for storage

conditions).

WITHHOLDING PERIODS: Nil.

ACVM No. A000935.

250 mL (125 doses)

[500 mL (250 doses)

MSD AH logo

Batch No.

Expiry

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