contains the active ingredient rabeprazole sodium
CONSUMER MEDICINE INFORMATION
What is in this leaflet
This leaflet answers some common
questions about ZABEP 20.
It does not contain all of the available
information. It does not take the place
of talking to your doctor or pharmacist.
All medicines have benefits and risks.
Your doctor has weighed the risks of
you taking ZABEP 20 against the
benefits they expect it will have for
If you have any concerns about
taking this medicine, talk to your
doctor or pharmacist.
Keep this leaflet with your medicine.
You may need to read it again.
What ZABEP 20 is used
ZABEP 20 is used to:
treat reflux oesophagitis or reflux
disease. This can be caused by
food and acid from the stomach
flowing the wrong way (reflux)
back up the food pipe, also known
as the oesophagus.
Reflux can cause a burning
sensation in the chest rising up the
throat, also known as heartburn.
help stop reflux oesophagitis from
coming back or relapsing
treat peptic ulcers. Depending on
the position of the ulcer it is called
a gastric or duodenal ulcer occurs
in the stomach. A duodenal ulcer
occurs in the duodenum which is
the tube leading out of the
These ulcers can be caused by too
much acid being made in the
Most people who have a peptic
ulcer also have a bacteria called
Helicobacter pylori in their
stomach. Your doctor may also
prescribe a course of antibiotics
(clarithromycin and amoxicillin) for
you. When ZABEP 20 is taken with
antibiotics, the combination therapy
will kill the Helicobacter pylori and
let your ulcer heal.
The presence of the bacteria
Helicobacter pylori may cause the
stomach to become inflamed,
resulting in pain, nausea and
vomiting. When ZABEP 20 is taken
with antibiotics, they will help kill
Helicobacter pylori and allow the
stomach to heal.
ZABEP 20 belongs to a group of
medicines called proton pump
inhibitors (PPIs). ZABEP 20 works by
decreasing the amount of acid the
stomach makes, to give relief from the
symptoms and allow healing to take
place. Your food will still be digested
in the normal way.
Your doctor may have prescribed
ZABEP 20 for another reason. Ask
your doctor if you have any questions
about why ZABEP 20 has been
prescribed for you.
ZABEP 20 is available only with a
Before you take ZABEP
When you must not take it
Do not take ZABEP 20 if you are
allergic to medicines containing
rabeprazole sodium, or any other
proton inhibitors (omeprazole,
pantoprazole) or any of the
ingredients listed at the end of this
Some of the symptoms of an allergic
reaction may include skin rash, itching
or hives, swelling of the face, lips or
tongue which may cause difficulty in
swallowing or breathing, wheezing or
shortness of breath.
Do not take ZABEP 20 if the expiry
date (Exp.) printed on the pack has
Do not take ZABEP 20 if the
packaging is torn or shows signs of
Before you start to take it
Tell your doctor if you are allergic to
any other medicines, foods, dyes or
Tell your doctor if you are pregnant
or plan to become pregnant.
Tell your doctor if you are
breastfeeding or wish to breastfeed.
Your doctor will discuss the risks and
benefits of taking ZABEP 20 when
Tell your doctor if you have, or ever
have had, liver disease.
If you have not told your doctor
about any of the above, tell them
before you start taking ZABEP 20.
Taking other medicines
Tell your doctor if you are taking any
other medicines, including any that
you buy without a prescription from
a pharmacy, supermarket or health
Some medicines may be affected by
ZABEP 20, or may affect how well it
works. These include:
digoxin, a medicine used to treat
ketoconazole, a medicine used to
treat fungal infections.
atazanavir, a medicine used (with
other antiretrovirals) to treat HIV-1
Your doctor can tell you what to do if
you are taking any of these medicines.
If you are not sure whether you are
taking any of these medicines, check
with your doctor or pharmacist.
Your doctor and pharmacist have more
information on medicines to be careful
with or avoid while taking ZABEP 20.
How to take ZABEP 20
How much to take
The usual dose is one tablet at the same
time each day. For treating
Helicobacter pylori infections in
combinations with antibiotics
(clarithromycin and amoxicillin), the
dose is one tablet twice each day,
morning and evening.
Your doctor may advise you to take a
different dose. This depends on your
condition and whether or not you are
taking any other medicines.
Follow all directions given to you by
your doctor and pharmacist
How to take ZABEP 20
Swallow the tablets with a glass of
Do not crush or chew the tablets.
They have a special coating, which
protects them from the acid in your
stomach. If you crush or chew ZABEP
20 tablets, they will not work as well. It
does not matter if you take ZABEP 20
with food or on an empty stomach.
If you forget to take ZABEP 20
If it is almost time for your next dose,
skip the dose you missed and take
your next dose when you are meant
Otherwise, take the missed dose as
soon as you remember, and then go
back to taking your tablets as you
Do not take a double dose to make up
for the dose you missed.
If you are not sure what to do, ask
your doctor or pharmacist.
How long to take ZABEP 20
Keep taking ZABEP 20 for as long as
your doctor recommends.
If you take too much ZABEP
Immediately telephone your doctor,
or the Poisons Information Centre
(telephone 13 11 26), or go to
Accident and Emergency at the
nearest hospital, if you think you or
anyone else may have taken too much
ZABEP 20. Do this even if there are
no signs of discomfort or poisoning.
You may need urgent medical attention.
While you are taking
Things you must do
Before starting any new medicine,
tell your doctor or pharmacist that
you are taking ZABEP 20.
Always swallow ZABEP 20 tablets
Tell all the doctors, dentists and
pharmacists who are treating you
that you are taking ZABEP 20.
Tell your doctor if you become
pregnant while taking ZABEP 20.
If you plan to have surgery, including
dental surgery, tell your doctor or
dentist that you are taking ZABEP
Things you must not do
Do not use ZABEP 20 to treat any
other conditions unless your doctor
tells you to.
Do not give ZABEP 20 to anyone
else, even if they have the same
condition as you.
Do not crush or chew the tablets.
Do not give ZABEP 20 to children.
Things that may help your
Some self help measures suggested
below may help your condition. Talk to
your doctor or pharmacist for more
information about these measures.
alcohol - your doctor may advise
you to limit your alcohol intake.
aspirin and many other medicines
used to treat arthritis/period
pain/headaches - these medicines
may irritate the stomach and may
make your condition worse. Your
doctor or pharmacist may suggest
other medicines you can take.
caffeine - your doctor may advise
you to limit the number of drinks
which contain caffeine, such as
coffee, tea, cocoa and cola drinks,
because they contain ingredients
that may irritate your stomach.
eating habits - eat smaller, more
frequent meals. Eat slowly and
chew your food carefully. Try not
to rush at meal times.
smoking - your doctor may advise
you to stop smoking or at least cut
weight - your doctor may suggest
losing some weight to help your
Tell your doctor or pharmacist as
soon as possible if you do not feel well
while you are taking ZABEP 20.
Like all other medicines, ZABEP 20
may have unwanted side effects in
some people. Sometimes they are
serious, most of the time they are not.
You may need medical treatment if you
get some of the side effects.
Do not be alarmed by this list of
possible side effects.
You may not experience any of them.
Ask your doctor or pharmacist to
answer any questions you may have.
Tell your doctor if you notice any of
the following and they worry you:
breast enlargement in men
itchy rash accompanied by skin
Tell your doctor immediately if you
notice any of the following:
bleeding or bruising more easily
signs of frequent infections such as
fever, severe chills, sore throat or
Tell your doctor immediately and do
not take your next dose of ZABEP 20
if you notice any of the following:
signs of allergy such as skin rash,
reddening, blister or itching,
swelling of the face, lips or other
parts of the body, shortness of
breath or wheezing.
Other side effects not listed above
may also occur in some patients. Tell
your doctor if you notice anything
that is making you feel unwell.
Other problems are more likely to
arise from the ulcer itself rather than
For these reasons contact your
doctor immediately if you notice any
of the following:
pain or indigestion
you begin to vomit blood or food
you pass black (blood-stained)
After using ZABEP 20
Keep ZABEP 20 where children
cannot reach it.
A locked cupboard at least one-and-a-
half metres above the ground is a good
place to store medicines.
Keep the tablets in their pack until it
is time to take them.
If you take the tablets out of the pack
they may not keep well.
Keep your tablets in a cool dry place
where the temperature stays below
Do not store ZABEP 20 or any other
medicine in the bathroom or near a
Do not leave ZABEP 20 in the car or
on window sills.
Heat and dampness can destroy some
If your doctor tells you to stop taking
ZABEP 20, or your tablets have
passed their expiry date, ask your
pharmacist what to do with any that
are left over.
What it looks like
ZABEP 20 - elliptical yellow tablet
with no markings.
Each carton of ZABEP 20 contains 30
enteric coated tablets.
The active ingredient in ZABEP 20 is
Each ZABEP 20 enteric coated tablet
contains 20 mg of rabeprazole sodium.
The tablets also contain:
methacrylic acid-ethyl acrylate
sodium lauryl sulphate
iron oxide yellow (E172)
titanium dioxide (E171).
The tablets do not contain gluten,
lactose, sucrose, tartrazine or any other
Alphapharm Pty Limited
(ABN 93 002 359 739)
Level 1, 30 The Bond
30-34 Hickson Road
Millers Point NSW 2000
Phone: (02) 9298 3999
Australian registration numbers:
ZABEP 20 - AUST R 191867
Date of preparation: May 2015.