Xifaxan 200 mg CMI February 2017
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XIFAXAN 200 mg Tablets
Consumer Medicine Information
What is in this Leaflet
This leaflet answers some common questions about
XIFAXAN 200 mg tablets.
It does not contain all the available information. It does not
take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits.
If you have any concerns about taking this medicine, ask
your doctor or pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
What XIFAXAN 200 mg is used for:
gastrointestinal tract and very little is absorbed. XIFAXAN
200 mg is used to treat travellers’ diarrhoea that is caused by
bacteria that do not invade the gut wall, in people aged 12
years and older. XIFAXAN is not effective for diarrhoea
caused by bacteria that invade the gut wall. There is no
experience using XIFAXAN to treat travellers’ diarrhoea in
children under 12 years of age. XIFAXAN may be prescribed
for you before you travel overseas, so you have it with you if
you need to treat an episode of diarrhoea.
Before you travel overseas, ask your doctor or
pharmacist if you have any questions about why
XIFAXAN has been prescribed for you, or how to use it.
Your doctor may have recommended XIFAXAN tablets for
Before you take XIFAXAN 200 mg
When you must not take it
Do not take XIFAXAN tablets if:
You have an allergy to rifaximin or any of the rifamycin
ingredient contained in this medicine, listed at the end
of this leaflet. Some of the symptoms of an allergic
reaction may include shortness of breath, wheezing or
difficulty breathing; swelling of the face, lips, tongue or
other parts of the body; rash, itchiness or hives on the
You have bowel obstruction (a blocked bowel)
You also have a fever, or blood in your stools. These
are signs that the diarrhoea may be caused by an
invasive bacteria that will not be effectively treated by
Do not take this medicine after the expiry date printed on
the pack or if the packaging is torn or shows signs of
tampering. If it has expired or is damaged, return it to your
pharmacist for disposal.
If you are not sure whether you should start taking this
medicine, see medical advice.
Before you start to take it
Tell your doctor if you have allergies to any other
medicines, foods, preservatives or dyes.
Tell your doctor if you are pregnant or plan to become
Your doctor can discuss with you the risks and benefits
Tell you doctor if you are breastfeeding.
It is not known if your baby can absorb rifaximin from breast
milk if you are breastfeeding.
If you have not told your doctor about any of the above,
tell him/her before you start taking XIFAXAN tablets.
Taking other medicines
Tell you doctor or pharmacist if you are taking any other
medicines, including any that you get without a
prescription from your pharmacy, supermarket or health
There is a possibility that XIFAXAN can interact with
other medicines, including ciclosporin, oral
contraceptives and warfarin.
Your doctor and pharmacist have more information on which
medicines to be careful with or avoid while taking this
How to take XIFAXAN 200 mg tablets
How much to take
The recommended dosage of XIFAXAN tablets is one
200 mg tablet three times a day for three days
(a total of 9 doses).
How to take it
Swallow the tablet whole with a glass of water. You can
take XIFAXAN tablets with or without food.
If you forget to take it
If it is nearly time for your next dose, skip the dose you
missed and take the next dose when you are meant to.
Otherwise, take it as soon as you remember, and then
go back to taking your medicine as you would normally.
Do not take a double dose to make up for the dose that
If you have trouble remembering to take your medicine, ask
your pharmacist for some hints.
If you take too much (overdose)
If in Australia, immediately telephone your doctor or the
advice, or go to the Accident and Emergency department at
the nearest hospital, if you think that you or anyone else may
have taken too many XIFAXAN tablets. If overseas, seek
discomfort or poisoning.
While you are using XIFAXAN tablets
Things you must do
Tell any other doctors, dentists, and pharmacists who
treat you that you are taking this medicine.
If you experience fever, if your diarrhoea becomes
worse, you have blood in your stools, or if symptoms
have not resolved after 3 days of treatment, then contact
a doctor for assessment. Do not take a second course of
Things you must not do
Do not take XIFAXAN tablets to treat any other
conditions unless your doctor tells you to.
Do not give your medicine to anyone else, even if they
have the same condition as you.
Do not stop taking your medicine or lower the dosage
without checking with your doctor.
Xifaxan 200 mg CMI February 2017
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If you stop taking it suddenly, your condition may worsen or
you may have unwanted side effects.
Tell a doctor or pharmacist as soon as possible if you
do not feel well while you are using XIFAXAN.
All medicines can have unwanted effects. Sometimes they
are serious, most of the time they are not. Do not be alarmed
by this list of possible side effects. You may not experience
any of them.
Ask a doctor or pharmacist to answer any questions
that you may have.
Tell your doctor or pharmacist if you notice any of the
following common side effects and they worry you:
wind, abdominal bloating, abdominal pain, constipation,
involuntary, painful, or ineffective straining on the toilet
The above list includes the more common side effects of
your medicine reported in adults being treated for traveller’s
diarrhoea. They are usually mild and short-lived.
Less common side effects include:
Thrush, cold sore, swollen throat, inflammation or
infection of the nose or throat
Loss of appetite, dehydration
Depressed mood, sleeplessness, nervousness
Cough, dry or sore throat, runny nose, shortness of
breath, blocked nose
Muscle cramps, muscle pain, back or neck pain
Chills, cold sweats, perspiration, flu-like illness
Rash, blotchy skin, hot flushes.
Tell your doctor as soon as possible if you notice any of
Diarrhoea. XIFAXAN, like nearly all antibiotics, can alter
the mix of bacteria in the intestine. This can lead to an
overgrowth of a bacteria called Clostridium difficile
(C. difficile). If you take XIFAXAN, there is a small risk
that you could experience diarrhoea caused by C.
difficile. If you develop severe diarrhoea after you have
stopped XIFAXAN, contact your doctor immediately.
As with other medicines there is a small risk of serious
allergic reactions. Consult your doctor immediately or
go to the Accident & Emergency department of your
nearest hospital if you notice any of the following:
swelling of the face, lips or tongue which may make
swallowing or breathing difficult
asthma, wheezing, shortness of breath
sudden or severe itching, skin rash, hives
Tell your doctor or pharmacist if you notice anything
that is making you feel unwell.
Other side effects not listed above may also occur in some
After using XIFAXAN tablets
Keep your tablets in the blister packaging until it is time
to take them
If you take the tablets out of the packaging they will not keep
temperature stays below 25˚C.
Do not store XIFAXAN tablets or any other medicines in
the bathroom or near a sink. Do not leave it on a window
sill or in the car.
Heat and dampness can destroy some medicines.
Keep it where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the
ground is a good place to store medicines.
If your doctor tells you stop taking this medicine or the
expiry date has passed, ask your pharmacist what to do
with any medicine that is left over.
What it looks like
XIFAXAN 200 mg tablets are pink, round, biconvex, film-
XIFAXAN tablets contains 200 mg of rifaximin as the active
ingredient. The tablets also contain:
Sodium starch glycolate Type A
Colloidal anhydrous silica
The film coating contains
Iron oxide red
XIFAXAN tablets are supplied in Australia by:
Norgine Pty Ltd
3/14 Rodborough Road
Frenchs Forest NSW 2086
Phone: 1800 766 936
This Leaflet was prepared in February 2017
Australian Registration No. AUST R 222643