Verapamil 120mg tablets

Main information

  • Trade name:
  • Verapamil 120mg tablets
  • Dosage:
  • 120mg
  • Pharmaceutical form:
  • Tablet
  • Administration route:
  • Oral
  • Class:
  • No Controlled Drug Status
  • Prescription type:
  • Valid as a prescribable product
  • Medicine domain:
  • Humans
  • Medicine type:
  • Allopathic drug

Documents

Localization

  • Available in:
  • Verapamil 120mg tablets
    United Kingdom
  • Language:
  • English

Therapeutic information

  • Product summary:
  • BNF: 02060200; GTIN: 5012617009777

Status

  • Source:
  • eMC
  • Authorization number:
  • PL 0142/0283
  • Last update:
  • 28-01-2019

Patient Information leaflet: composition, indications, side effects, dosage, interactions, adverse reactions, pregnancy, lactation

you must only take this medicine if you are

breast-feeding if your doctor thinks it is necessary.

Driving and using machines

When starting Verapamil tablets, you may find that your

ability to drive a car or use machinery is impaired. You should

take care when driving or using machines until you know how

you react to this medicine.

Verapamil tablets contains

lactose (a type of sugar). If your doctor has told you that

you cannot tolerate some sugars, see your doctor before

taking this medicine.

sunset yellow (E110), which may cause allergic

reactions.

Always take Verapamil tablets exactly as your doctor or

pharmacist has told you. Check with your doctor or

pharmacist if you are not sure. Swallow this medicine with

a glass of water

Adults

The recommended dose is:

For high blood pressure: 120 mg twice a day. Your doctor

may increase this to a maximum of 160 mg two or three

times a day.

For angina: 120 mg three times a day. Your doctor may

lower this dose.

For heart rhythm disorders: 40 mg to 120 mg three times a

day.

Elderly

The dose will be the same as that for adults. If you have a

liver or kidney problem, your doctor may lower your dose.

Children

The doctor will decide if this medicine is suitable for your

child, depending on your child’s condition and age.

The recommended dose for children is:

Up to 2 years of age: 20 mg two or three times a day.

2 years of age and above: 40 mg to 120 mg two or three

times a day.

If you take more Verapamil tablets than you should

Talk to a doctor or go to a hospital straight away. Take the

medicine pack with you so the doctor knows what you have

taken.

If you forget to take Verapamil tablets

Take your tablets as soon as you remember. However, if it is

nearly time for the next dose, skip the missed dose. Do not

take a double dose (two doses at the same time) to make up

for a forgotten dose.

If you stop taking Verapamil tablets

Do not stop taking this medicine without talking to your doctor

first. If you stop taking this medicine it may make your

condition worse.

If you have any further questions on the use of this medicine,

ask your doctor or pharmacist.

Like all medicines, Verapamil tablets can cause side effects,

although not everybody gets them.

If you have any of the following side effects, STOP

TAKING this medicine and see a doctor or go to a

hospital straight away:

yellowing of the skin or eyes, a fever or tenderness

around the middle. These are signs that your liver may

not be functioning as well as usual.

an allergic reaction which may cause an itchy skin rash,

flaking skin, red and raised lumps (hives), blistering of

your skin, mouth, eyes or genitals, sudden wheezing,

fluttering or tightness of your chest or collapse, swelling

of your face, lips, tongue or throat or difficulty in breathing

or swallowing

heart problems such as low blood pressure (hypotension),

slow heart beats, unusual heart beats, heart attack or

heart failure. This is more likely if you are taking high

doses or you already have damage to your heart

swelling of the limbs

If you get any of the following side effects, see your

doctor as soon as possible:

swelling of your blood vessels which may show as pain in

the fingers and toes

numbness or tingling

muscle or joint pain

The most common side effect is constipation. Other side

effects include;

muscle weakness

tremor or movement disorders

breast development in older men or breasts start to

produce milk (males and females). These effects are rare

and are resolved upon stopping taking the tablets

difficulty in getting an erection

flushing of your face

skin rash or itching

hair loss

headaches, feeling dizzy or tired

tinnitus (ringing or buzzing in the ears)

vertigo

abdominal pain or discomfort

feeling sick (nausea) or being sick (vomiting)

swollen and overgrown gums

This medicine may also cause an increase in levels of a

hormone called prolactin. This will only be detected through

tests performed by your doctor.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist.

This includes any possible side effects not listed in this

leaflet. You can also report side effects directly via the Yellow

Card Scheme at www.mhra.gov.uk/yellowcard.

Keep this medicine out of the sight and reach of

children.

Do not store above 25°C. Store in the original package to

protect from light or store in the original container and keep

the container tightly closed.

Do not use this medicine after the expiry date, which is stated

on the package or container. The expiry date refers to the

last day of that month.

Do not throw away any medicines via wastewater or

household waste. Ask your pharmacist how to throw away

medicines you no longer use. These measures will help to

protect the environment.

What Verapamil tablets contain

The active substance (the ingredient that makes the tablets

work) is verapamil hydrochloride.

The other ingredients in the tablets are maize starch, lactose,

gelatin, magnesium stearate, colloidal anhydrous silica, talc,

titanium dioxide (E171), quinoline yellow (E104), sunset

yellow

(E110),

hydroxypropyl

cellulose,

hydroxypropyl

methylcellulose, ethylcellulose and diethyl phthalate.

What Verapamil tablets look like and contents of the

pack

Verapamil tablets are round, convex, pale yellow, film coated

tablets with a marking engraved on one side.

The 40 mg tablets are engraved with MP68 and have a

diameter of approximately 6.5 mm.

The 80 mg tablets are engraved with MP69 and have a

diameter of approximately 8 mm.

The 120 mg tablets are engraved with MP70 and have a

diameter of approximately 9.5 mm.

Al three strengths of Verapamil Tablets come in blister packs

of 28 and 84 tablets and in containers of 100 and 500 tablets.

Not all pack sizes may be marketed.

Marketing Authorisation Holder

Genethics Europe Limited,

41 – 43 Klimentos, Klimentos Tower,

Nicosia 1061, Cyprus

Manufacturer

DDSA Pharmaceuticals Limited,

84 Pembroke Road,

London, W8 6NX, UK

For more information about this product, please contact the

Marketing Authorisation Holder.

This leaflet was last revised in 10/2017

GE0038-0039-0040/O/PIL/GE2

PACKAGE LEAFLET: INFORMATION FOR THE USER

VERAPAMIL 40 mg, 80 mg

& 120 mg TABLETS

Verapamil hydrochloride

1. What Verapamil tablets are and what they

are used for

2. What you need to know before you take

Verapamil tablets

3. How to take Verapamil tablets

4. Possible side effects

5. How to store Verapamil tablets

6. Contents of the pack and other information

Verapamil

belongs

group

medicines

called

calcium channel blockers. The heart muscle and the

muscle in your blood vessel walls need calcium to contract

and tighten.

Verapamil stops calcium from getting into these muscles.

This

relaxes your heart and blood vessels

makes your heart pump out less blood every time it beats

slows down your heart rate (pulse).

Verapamil can be used to:

treat high blood pressure (hypertension). It may be

prescribed on its own or in combination with other heart

medicines

treat and prevent chest pain (angina)

treat and prevent heart rhythm problems such as heart

flutter (supraventricular tachycardia).

If you are not sure why you have been prescribed this

medicine then please ask your doctor.

Do not take Verapamil tablets and tell your doctor if

you:

are allergic to Verapamil or any other ingredients in the

tablets (listed in section 6 of this leaflet). The signs of an

allergic reaction include a rash, itching or shortness of

breath

have second or third-degree atrioventricular block or

sino-atrial block. This is a disorder where parts of your

heart may beat at the wrong time causing it not to pump

blood around the body very well

have a heart beat disorder, such as sick sinus syndrome,

Wolff-Parkinson-White syndrome or

Lown-Ganong-Levine syndrome

have a problem where your heart beats very slowly

(severe bradycardia)

have low blood pressure (hypotension)

are being treated with ivabradine (for heart conditions)

have an inherited blood disorder known as porphyria.

Do not take this medicine if any of the above apply to you. If

you are not sure, talk to your doctor or pharmacist before

taking this medicine.

You will not be given Verapamil tablets if you:

have a sudden and rapid fall in blood pressure

(cardiogenic shock)

have heart failure that is not being treated

have a sudden heart attack, particularly if you have a

slow heart beat, low blood pressure or a type of heart

failure called ‘left ventricular failure’.

You will not be given this medicine if any of the above apply

to you. If you are not sure, talk to your doctor or pharmacist

before taking this medicine.

Warnings and precautions

Tell your doctor before you take this medicine if you:

have liver or kidney problems

have first degree atrioventricular block. This is a disorder

where parts of your heart may beat at the wrong time

causing it not to pump blood around the body very well

have a condition where the nerve to muscle transmission

is affected e.g. myasthemia gravis, Lambert-Eaton

syndrome, advanced Duchenne muscular dystrophy.

are pregnant or breast-feeding (see ‘Pregnancy and

breast-feeding’ section)

If you are not sure if any of the above apply to you, talk to

your doctor or pharmacist before taking this medicine.

Tests and operations while you are taking Verapamil

tablets

your doctor may monitor your blood pressure regularly

if you are going to be given an anaesthetic, tell the doctor

or dentist that you are taking Verapamil tablets.

Other medicines and Verapamil tablets

Tell your doctor or pharmacist if you are taking, have recently

taken or might take any other medicines, including medicines

bought without a prescription. This is because Verapamil

tablets can affect the way some medicines work. Also some

medicines can affect the way Verapamil tablets works.

In particular, tell your doctor or pharmacist if you are taking

any of the following:

Medicines to treat heart failure, such as Digoxin, Digitoxin

or Eplerenone

Medicines used to lower blood pressure and treat

abnormal heart rhythms, such as beta blockers

(e.g. Atenolol, Metoprolol or Propranolol), Alpha blockers

(e.g. Prazosin and Terazosin), Amiodarone,

Disopyramide, Flecainide or Quinidine

Dabigatran, used to thin the blood

Medicines containing ivabradine for the treatment of

certain heart diseases

Simvastatin, atorvastatin or lovastatin used to lower

cholesterol levels

Diuretics (also called ‘water pills’)

Medicines to treat epilepsy, such as Carbamazepine,

Phenytoin, Phenobarbital or Primidone

Midazolam used to make you sleepy

Lithium to treat mental health problems

Medicines to treat depression, such as Amitriptyline or

Imipramine and the herbal product St John’s Wort

Buspirone to treat anxiety

Theophylline to treat asthma

Rifampicin to treat TB (tuberculosis)

Atazanavir or Ritonavir to treat HIV (Human

Immunodeficiency Virus)

Clarithromycin, Erythromycin or Telithromycin to treat

bacterial infections

Cimetidine to treat stomach ulcers

Ciclosporin, Everolimus, Sirolimus or Tacrolimus used to

stop the rejection of organs after transplants

Glibenclamide, used to treat certain types of diabetes

Aspirin, a non-steroidal anti-inflammatory painkiller

(NSAID) used to relieve pain and reduce fever

Almotriptan, used to treat migraine

Injected Dantrolene to treat severe muscle spasms

Muscle relaxants, such as Atracurium or Suxamethonium

Darifenacin to treat urinary problems

Dutasteride to treat an enlarged prostate gland.

Doxorubicin, an anti-cancer medicine

Colchicine or suplfinpyrazone used to treat gout

If you go into hospital or have treatment for other conditions,

tell the doctor you are taking Verapamil tablets

Verapamil tablets with food and drink

do not drink grapefruit juice whilst taking Verapamil

tablets. This is because grapefruit juice may change the

blood levels of your medicine

you should monitor the amount of alcohol you drink

whilst taking Verapamil tablets. This is because

Verapamil can affect the way the body gets rid of alcohol.

This means that you may not have to drink as much for

your blood alcohol levels to be above the legal limit to

drive. It will also take you longer to sober up.

Pregnancy and breast-feeding

Talk to your doctor before taking this medicine if you are

pregnant, think you might be pregnant, planning to have a

baby or are breast-feeding.

you must only take this medicine in the first 3 months of

pregnancy (1st trimester) if your doctor thinks it is

essential

Read all of this leaflet carefully before you start taking

this

medicine

because

it

contains

important

information for you.

- Keep this leaflet. You may need to read it again.

- If you have any further questions, ask your doctor or

pharmacist.

- This medicine has been prescribed for you only.

Do not pass it on to others. It may harm them, even if

their signs of illness are the same as yours.

- If you get any side effects talk to your doctor or

pharmacist. This includes any possible side effects not

listed in this leaflet. See section 4.

This leaflet contains

2. What you need to know before you

take Verapamil tablets

1. What Verapamil tablets are and what

they are used for

you must only take this medicine if you are

breast-feeding if your doctor thinks it is necessary.

Driving and using machines

When starting Verapamil tablets, you may find that your

ability to drive a car or use machinery is impaired. You should

take care when driving or using machines until you know how

you react to this medicine.

Verapamil tablets contains

lactose (a type of sugar). If your doctor has told you that

you cannot tolerate some sugars, see your doctor before

taking this medicine.

sunset yellow (E110), which may cause allergic

reactions.

Always take Verapamil tablets exactly as your doctor or

pharmacist has told you. Check with your doctor or

pharmacist if you are not sure. Swallow this medicine with

a glass of water

Adults

The recommended dose is:

For high blood pressure: 120 mg twice a day. Your doctor

may increase this to a maximum of 160 mg two or three

times a day.

For angina: 120 mg three times a day. Your doctor may

lower this dose.

For heart rhythm disorders: 40 mg to 120 mg three times a

day.

Elderly

The dose will be the same as that for adults. If you have a

liver or kidney problem, your doctor may lower your dose.

Children

The doctor will decide if this medicine is suitable for your

child, depending on your child’s condition and age.

The recommended dose for children is:

Up to 2 years of age: 20 mg two or three times a day.

2 years of age and above: 40 mg to 120 mg two or three

times a day.

If you take more Verapamil tablets than you should

Talk to a doctor or go to a hospital straight away. Take the

medicine pack with you so the doctor knows what you have

taken.

If you forget to take Verapamil tablets

Take your tablets as soon as you remember. However, if it is

nearly time for the next dose, skip the missed dose. Do not

take a double dose (two doses at the same time) to make up

for a forgotten dose.

If you stop taking Verapamil tablets

Do not stop taking this medicine without talking to your doctor

first. If you stop taking this medicine it may make your

condition worse.

If you have any further questions on the use of this medicine,

ask your doctor or pharmacist.

Like all medicines, Verapamil tablets can cause side effects,

although not everybody gets them.

If you have any of the following side effects, STOP

TAKING this medicine and see a doctor or go to a

hospital straight away:

yellowing of the skin or eyes, a fever or tenderness

around the middle. These are signs that your liver may

not be functioning as well as usual.

an allergic reaction which may cause an itchy skin rash,

flaking skin, red and raised lumps (hives), blistering of

your skin, mouth, eyes or genitals, sudden wheezing,

fluttering or tightness of your chest or collapse, swelling

of your face, lips, tongue or throat or difficulty in breathing

or swallowing

heart problems such as low blood pressure (hypotension),

slow heart beats, unusual heart beats, heart attack or

heart failure. This is more likely if you are taking high

doses or you already have damage to your heart

swelling of the limbs

If you get any of the following side effects, see your

doctor as soon as possible:

swelling of your blood vessels which may show as pain in

the fingers and toes

numbness or tingling

muscle or joint pain

The most common side effect is constipation. Other side

effects include;

muscle weakness

tremor or movement disorders

breast development in older men or breasts start to

produce milk (males and females). These effects are rare

and are resolved upon stopping taking the tablets

difficulty in getting an erection

flushing of your face

skin rash or itching

hair loss

headaches, feeling dizzy or tired

tinnitus (ringing or buzzing in the ears)

vertigo

abdominal pain or discomfort

feeling sick (nausea) or being sick (vomiting)

swollen and overgrown gums

This medicine may also cause an increase in levels of a

hormone called prolactin. This will only be detected through

tests performed by your doctor.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist.

This includes any possible side effects not listed in this

leaflet. You can also report side effects directly via the Yellow

Card Scheme at www.mhra.gov.uk/yellowcard.

Keep this medicine out of the sight and reach of

children.

Do not store above 25°C. Store in the original package to

protect from light or store in the original container and keep

the container tightly closed.

Do not use this medicine after the expiry date, which is stated

on the package or container. The expiry date refers to the

last day of that month.

Do not throw away any medicines via wastewater or

household waste. Ask your pharmacist how to throw away

medicines you no longer use. These measures will help to

protect the environment.

What Verapamil tablets contain

The active substance (the ingredient that makes the tablets

work) is verapamil hydrochloride.

The other ingredients in the tablets are maize starch, lactose,

gelatin, magnesium stearate, colloidal anhydrous silica, talc,

titanium dioxide (E171), quinoline yellow (E104), sunset

yellow

(E110),

hydroxypropyl

cellulose,

hydroxypropyl

methylcellulose, ethylcellulose and diethyl phthalate.

What Verapamil tablets look like and contents of the

pack

Verapamil tablets are round, convex, pale yellow, film coated

tablets with a marking engraved on one side.

The 40 mg tablets are engraved with MP68 and have a

diameter of approximately 6.5 mm.

The 80 mg tablets are engraved with MP69 and have a

diameter of approximately 8 mm.

The 120 mg tablets are engraved with MP70 and have a

diameter of approximately 9.5 mm.

Al three strengths of Verapamil Tablets come in blister packs

of 28 and 84 tablets and in containers of 100 and 500 tablets.

Not all pack sizes may be marketed.

Marketing Authorisation Holder

Genethics Europe Limited,

41 – 43 Klimentos, Klimentos Tower,

Nicosia 1061, Cyprus

Manufacturer

DDSA Pharmaceuticals Limited,

84 Pembroke Road,

London, W8 6NX, UK

For more information about this product, please contact the

Marketing Authorisation Holder.

This leaflet was last revised in 10/2017

GE0038-0039-0040/O/PIL/GE2

3. How to take Verapamil tablets

4. Possible side effects

5. How to store Verapamil tablets

6. Contents of the pack and other

information

PACKAGE LEAFLET: INFORMATION FOR THE USER

VERAPAMIL 40 mg, 80 mg

& 120 mg TABLETS

Verapamil hydrochloride

1. What Verapamil tablets are and what they

are used for

2. What you need to know before you take

Verapamil tablets

3. How to take Verapamil tablets

4. Possible side effects

5. How to store Verapamil tablets

6. Contents of the pack and other information

Verapamil

belongs

group

medicines

called

calcium channel blockers. The heart muscle and the

muscle in your blood vessel walls need calcium to contract

and tighten.

Verapamil stops calcium from getting into these muscles.

This

relaxes your heart and blood vessels

makes your heart pump out less blood every time it beats

slows down your heart rate (pulse).

Verapamil can be used to:

treat high blood pressure (hypertension). It may be

prescribed on its own or in combination with other heart

medicines

treat and prevent chest pain (angina)

treat and prevent heart rhythm problems such as heart

flutter (supraventricular tachycardia).

If you are not sure why you have been prescribed this

medicine then please ask your doctor.

Do not take Verapamil tablets and tell your doctor if

you:

are allergic to Verapamil or any other ingredients in the

tablets (listed in section 6 of this leaflet). The signs of an

allergic reaction include a rash, itching or shortness of

breath

have second or third-degree atrioventricular block or

sino-atrial block. This is a disorder where parts of your

heart may beat at the wrong time causing it not to pump

blood around the body very well

have a heart beat disorder, such as sick sinus syndrome,

Wolff-Parkinson-White syndrome or

Lown-Ganong-Levine syndrome

have a problem where your heart beats very slowly

(severe bradycardia)

have low blood pressure (hypotension)

are being treated with ivabradine (for heart conditions)

have an inherited blood disorder known as porphyria.

Do not take this medicine if any of the above apply to you. If

you are not sure, talk to your doctor or pharmacist before

taking this medicine.

You will not be given Verapamil tablets if you:

have a sudden and rapid fall in blood pressure

(cardiogenic shock)

have heart failure that is not being treated

have a sudden heart attack, particularly if you have a

slow heart beat, low blood pressure or a type of heart

failure called ‘left ventricular failure’.

You will not be given this medicine if any of the above apply

to you. If you are not sure, talk to your doctor or pharmacist

before taking this medicine.

Warnings and precautions

Tell your doctor before you take this medicine if you:

have liver or kidney problems

have first degree atrioventricular block. This is a disorder

where parts of your heart may beat at the wrong time

causing it not to pump blood around the body very well

have a condition where the nerve to muscle transmission

is affected e.g. myasthemia gravis, Lambert-Eaton

syndrome, advanced Duchenne muscular dystrophy.

are pregnant or breast-feeding (see ‘Pregnancy and

breast-feeding’ section)

If you are not sure if any of the above apply to you, talk to

your doctor or pharmacist before taking this medicine.

Tests and operations while you are taking Verapamil

tablets

your doctor may monitor your blood pressure regularly

if you are going to be given an anaesthetic, tell the doctor

or dentist that you are taking Verapamil tablets.

Other medicines and Verapamil tablets

Tell your doctor or pharmacist if you are taking, have recently

taken or might take any other medicines, including medicines

bought without a prescription. This is because Verapamil

tablets can affect the way some medicines work. Also some

medicines can affect the way Verapamil tablets works.

In particular, tell your doctor or pharmacist if you are taking

any of the following:

Medicines to treat heart failure, such as Digoxin, Digitoxin

or Eplerenone

Medicines used to lower blood pressure and treat

abnormal heart rhythms, such as beta blockers

(e.g. Atenolol, Metoprolol or Propranolol), Alpha blockers

(e.g. Prazosin and Terazosin), Amiodarone,

Disopyramide, Flecainide or Quinidine

Dabigatran, used to thin the blood

Medicines containing ivabradine for the treatment of

certain heart diseases

Simvastatin, atorvastatin or lovastatin used to lower

cholesterol levels

Diuretics (also called ‘water pills’)

Medicines to treat epilepsy, such as Carbamazepine,

Phenytoin, Phenobarbital or Primidone

Midazolam used to make you sleepy

Lithium to treat mental health problems

Medicines to treat depression, such as Amitriptyline or

Imipramine and the herbal product St John’s Wort

Buspirone to treat anxiety

Theophylline to treat asthma

Rifampicin to treat TB (tuberculosis)

Atazanavir or Ritonavir to treat HIV (Human

Immunodeficiency Virus)

Clarithromycin, Erythromycin or Telithromycin to treat

bacterial infections

Cimetidine to treat stomach ulcers

Ciclosporin, Everolimus, Sirolimus or Tacrolimus used to

stop the rejection of organs after transplants

Glibenclamide, used to treat certain types of diabetes

Aspirin, a non-steroidal anti-inflammatory painkiller

(NSAID) used to relieve pain and reduce fever

Almotriptan, used to treat migraine

Injected Dantrolene to treat severe muscle spasms

Muscle relaxants, such as Atracurium or Suxamethonium

Darifenacin to treat urinary problems

Dutasteride to treat an enlarged prostate gland.

Doxorubicin, an anti-cancer medicine

Colchicine or suplfinpyrazone used to treat gout

If you go into hospital or have treatment for other conditions,

tell the doctor you are taking Verapamil tablets

Verapamil tablets with food and drink

do not drink grapefruit juice whilst taking Verapamil

tablets. This is because grapefruit juice may change the

blood levels of your medicine

you should monitor the amount of alcohol you drink

whilst taking Verapamil tablets. This is because

Verapamil can affect the way the body gets rid of alcohol.

This means that you may not have to drink as much for

your blood alcohol levels to be above the legal limit to

drive. It will also take you longer to sober up.

Pregnancy and breast-feeding

Talk to your doctor before taking this medicine if you are

pregnant, think you might be pregnant, planning to have a

baby or are breast-feeding.

you must only take this medicine in the first 3 months of

pregnancy (1st trimester) if your doctor thinks it is

essential