APVMA Approval No:
VAXSAFE MG VACCINE (LIVING)
35907 / 107711
VAXSAFE MG VACCINE (LIVING)
FOR ANIMAL TREATMENT ONLY
Each dose contains >10 7.0 CCU* living, attenuated, temperature-sensitive Mycoplasma
gallisepticum vaccine Strain ts-11.
*Colour Changing Units
Statement of Claims: An aid in the control of chronic respiratory disease (CRD) caused by
M. gallisepticum (MG) in susceptible (MG free) chickens at risk of infection.
Susceptible (MG free) layer flocks vaccinated with Vaxsafe® MG vaccine prior to MG
challenge exhibit less respiratory disease, require less anti-microbial medication and during
lay will produce more eggs than comparably challenged non-vaccinated flocks. Safety
testing has shown M. gallisepticum Strain ts-11 to be virtually non-pathogenic in chickens
and not readily transmitted between birds.
30mL (2000 doses)
Directions for Use:
Direction for Use
This product is contraindicated for vaccinating unhealthy birds.
This product is contraindicated for vaccination of birds undergoing medication with an
antimicrobial known to inhibit M. gallisepticum multiplication, eg, Tetracycline, Tiamulin,
Tylosin, Enrofloxacin, Lincospectin, Gentamycin or macrolide antibiotics.
Vaxsafe® MG contains live organisms and correct storage and administration are
essential for successful use.
Do not refreeze Vaxsafe® MG after thawing.
Withdraw antibiotics from the flock for a period equivalent to the recommended
withholding period prior to vaccination and do not use after vaccination.
Where antibiotics must be used, preference should be given to agents with low
mycoplasma activity such as penicillin, amoxycillin or neomycin. They should not be given
within 4 weeks after vaccination.
Do not dilute. Thawed vaccine should be used as supplied.
Dosage and Administration
Pullets are normally vaccinated between 6-14 weeks of age with the minimum age for
efficacious use being 4 weeks.
Application is by eye drop.
All birds in the flock should be vaccinated.
Vaccination need only be done once. Revaccination is not necessary and is not
Method of Vaccination:
Thaw unopened vials rapidly in a large (5 – 10 L) volume of warm (35 oC) water and use
within 1 hour after thawing. Mix the contents of the vial by gentle agitation during thawing.
Invert the bottle repeatedly following thawing to ensure the contents have resuspended.
If held at room temperature, use the entire contents immediately.
Remove the aluminium seal and rubber stopper before inserting a plastic dropper tip
supplied with the vaccine. Each drop should be ~15 microlitres of vaccine.
Hold each bird with its head tilted to one side.
Invert the dropper bottle allowing a single drop to form at the tip and fall freely into the
open eye, gently flooding it. The drop (before release) and tip should NOT touch the eye
Allow the bird to blink before releasing it.
Pullets should first be tested for MG infection. Testing for the presence of MG in the flock
is normally by way of the rapid serum agglutination test (RSAT) with blood samples being
tested within 24 hours of collection.
Operators should contact their laboratory service for advice on the collection and number
of blood samples to be taken.
Only flocks with no antibodies to MG should be vaccinated. Vaccination of infected birds
will not provide any economic benefit.
Vaccination should be carried out on MG free birds at least 3 weeks before exposure to
virulent MG is likely to occur.
Vaccination can be timed to coincide with other flock management practices (e.g. beak
trimming, Vaxsafe® MS (Mycoplasma synoviae) and fowl pox vaccination).
USER SAFETY INFORMATION:
If vaccine is accidentally splashed into the operator’s eyes, the eyes and face should
be thoroughly washed with water to avoid any potential reaction to culture medium
Additional information is available on the product Safety Data Sheet.
First Aid Instructions:
If poisoning occurs, contact a Doctor or Poisons Information Centre on 13 11 26.
First Aid Warnings:
Discard unused vaccine and empty vaccine bottles into a disinfectant solution (e.g. chlorine
based bleach). Dispose of any such inactivated, unused vaccine and empty containers by
wrapping in paper and putting in garbage.
In cases of spillage, soak up the liquid with an absorbent sponge or cloth and incinerate.
Treat the surface with a disinfectant solution (e.g. chlorine based bleach).
Vaxsafe® MG should always be protected from direct sunlight. For long term storage
Vaxsafe® MG should be stored at or below -70 oC. For short term storage (maximum of 4
weeks) Vaxsafe® MG can be stored in a domestic chest freezer (at or below -18 oC).