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Twin

Main information

  • Trade name:
  • Twin Pack Two Collars Bob Martin 15% w/w Flea and Tick for Dogs and Puppies over 12 weeks old
  • Available from:
  • Virbac S.A.
  • Medicine domain:
  • Animals
  • Medicine type:
  • Allopathic drug
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Documents

Localization

  • Available in:
  • Twin Pack Two Collars Bob Martin 15% w/w Flea and Tick for Dogs and Puppies over 12 weeks old
    United Kingdom
  • Language:
  • English

Other information

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Status

  • Source:
  • VMD - Veterinary Medicines Directorate
  • Authorization status:
  • Expired
  • Authorization number:
  • 05653/4095
  • Last update:
  • 21-12-2016

Summary of Product characteristics

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Revised: 17 December 2008

AN: 00737/2008

SUMMARY OF PRODUCT CHARACTERISTICS

1. NAME OF THE VETERINARY MEDICINAL PRODUCT

Twin-Pack Two Collars Bob Martin 15%w/w Flea and Tick for Dogs and Puppies over 12 Weeks

Old

2. QUALITATIVE AND QUANTITATIVE COMPOSITION

Each collar of

Contains:

Active ingredient

Dimpylate 15 % w / w……………………………………..

Excipients

For pink collar:

Lithol Rubine K4566 - 0.001 % w / w…………………...

Titanium dioxide (E171) 0.45 % w / w………................

For black collar:

Flash black 19976 0.026 % w / w………......................

0.01066g

For brown collar:

Flash black 19976 0.0087 % w / w………....................

Red ferric oxide (E172) 0.035 % w / w…………………

For red collar:

Ariabel scarlet 0.5 % w / w……………………...............

Or

Lithol rubine K4566 0.1 % w / w…………………………

For beige collar:

Flash beige 40232 – 0.3 % w / w………………………..

For green collar:

Tartrazine lake (E102) 0.28 % w / w…………………….

Blue alphazurine lake 0.12 % w / w……………………..

Titanium dioxide (E171) 0.1 % w / w……………………

For blue collar:

Flash blue 47949 – 0.16 % w / w………………………..

For yellow collar:

Titanium dioxide (E171) 0.12 % w / w………………….

Quinoline yellow aluminium lake (E104) 0.48% w/w….

Or

Flash yellow 47948 – 0.3 % w / w……………………….

For white collar:

Titanium dioxide (E171) 0.15 % w / w………………….

On the active strip, a reflective band may be attached.

24g

3.6g

0.0002g

0.108g

0.00624g

0.002088g

0.0084g

0.12g

0.024g

0.072g

0.0672g

0.0288g

0.024g

0.0384g

0.0288g

0.1152g

0.072g

39.2g

5.88g

0.000392g

0.1764g

0.010192g

0.0034104g

0.01372g

0.196g

0.0392g

0.1176g

0.10976g

0.04704g

0.0392g

0.06272g

0.04704g

0.18816g

0.1176g

41g

6.15g

0.00041g

0.1845g

0.003567g

0.01435g

0.205g

0.041g

0.123g

0.1148g

0.0492g

0.041g

0.0656g

0.0492g

0.1968g

0.123g

0.615g

1

Revised: 17 December 2008

AN: 00737/2008

3. PHARMACEUTICAL FORM

Collar.

Coloured supple plastic strip provided with a buckle.

4. CLINICAL PARTICULARS

4.1 Target species

Dogs.

4.2 Indications for use, specifying the target species

For the control of fleas and ticks on dogs for up to 5 months.

4.3 Contraindications

Do not use on puppies under 12 weeks of age.

4.4 Special warnings for each target species

Do not allow animals to chew the collar.

Fleas from pets often infest animal’s basket, bedding and regular resting areas such as carpets

and soft furnishings which should be treated with a suitable insecticide and vacuumed regularly.

4.5 Special precautions for use

i. Special precautions for use in animals

For external use only.

ii. Special precautions for the person administering the veterinary medicinal product to

animals

Wash hands thoroughly after handling the collar.

Dimpylate is an organophosphorus compound: DO NOT handle the collar if under medical

advice not to work with ANTICHOLINESTERASES.

Do not allow children to play with collar. Do not allow children to suck or chew the collar.

Do not smoke, eat or drink while handling the collar.

DO NOT SLEEP WITH PETS WEARING FLEA COLLARS.

IF YOU FEEL UNWELL FOLLOWING THE USE OF THIS PRODUCT, SEEK MEDICAL

ADVICE.

4.6 Adverse reactions (frequency and seriousness)

Remove collar immediately should any signs of skin irritation or adverse reaction occur.

REMOVE COLLAR FROM DOG IMMEDIATELY SHOULD ANY SIGNS OF DROWSINESS,

LISTLESSNESS, TREMOR, HYPERSALIVATION OR RESPIRATORY DIFFICULTIES DEVELOP

SOON AFTER FIXING OF COLLAR

4.7 Use during pregnancy, lactation or lay

Not for use on nursing or lactating bitches.

Remove fleas from young puppies and nursing bitches by careful use of a flea comb.

2

Revised: 17 December 2008

AN: 00737/2008

4.8 Interaction with other medicinal products and other forms of interaction

Do not use any other insecticides while the collar is being worn or within 7 days of removal.

4.9 Amounts to be administered and administration route

Remove collar from pack and fasten around the dog’s neck. When fitted to the growing dog, ensure

the collar is loosened as the animal grows. In the fully-grown dog, correct fitting will allow two

fingers to be inserted between the collar and the neck. Any excess length of collar extending

beyond the buckle should be cut and disposed of with the domestic refuse.

The collar does not need to be removed when the animal is being bathed as insecticidal activity

remains unaffected by water. Leave in place until the collar’s effective life is exhausted.

Replace after 5 months if reinfestation with fleas or ticks is a risk.

Insecticidal collar for dogs weighing 24 g and 60 cm in length.

Insecticidal collar for large dogs weighing 41 g and 65 cm in length.

Bicoloured brown and phosphorescent insecticidal collar weighing 39 g and 65 cm in length.

4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary

Dimpylate is an organophosphorus insecticide and atropine is antidotal.

Remove collar immediately if any signs of skin irritation or adverse reactions occur. Signs of

overdosage include drowsiness, listlessness, tremor, hypersalivation or respiratory difficulty.

4.11 Withdrawal period

Not applicable

5. PHARMACOLOGICAL PROPERTIES

ATC Vet Code: QP53AF03

The collars contain dimpylate as a parasiticide.

5.1 Pharmacodynamic properties

Dimpylate, an organophosphorus parasiticide is active against common fleas (Ctenocephalides)

and ticks (Rhipicephalus or Dermacentor) of dogs. It acts mainly by inhibiting insect enzymes such

as cholinesterases. This is achieved when dimpylate competes with acetylcholine, responsible for

nerve impulses, by binding to the esterase site of the cholinesterase molecules.

Acetylcholine, degraded at a lower pace, accumulates and induces disorders. Because the

metabolism of dimpylate in insects is very slow, irreversible poisoning is achieved.

5.2 Pharmacokinetic properties

In mammals, cholinesterase activity similarly decreases. However, this is only transitory since

enzyme synthesis is resumed and dimpylate is degraded within a very-short period of time.

Dimpylate being slowly released from the collar matrix, the product remains active for up to

5 months.

3

Revised: 17 December 2008

AN: 00737/2008

6. PHARMACEUTICAL PARTICULARS

6.1 List of excipients

Dyes

Flash black 19976…………………………………………………………………for black collar

Flash black 19976 and red ferric oxide………………………………………… for brown collar

Ariabel scarlet or lithol rubine K4566………………………………………….…for red collar

Flash beige 40232…………………………………………………………………for beige collar

Tartrazine lake (E102), blue alphazurine lake and titanium dioxide………….for green collar

Flash blue 47949…………………………………………………………………..for blue collar

Titanium dioxide (E171) and quinoline yellow aluminium lake (E104) or

flash yellow 47948………………………………………………………………….for yellow collar

Titanium dioxide……………………………………………………………………for white collar

Titanium dioxide and lithol rubine K4566………………………………………..for pink collar

Lankromark LN193, Ferric Oxide Red (E172) and

vegetable charcoal………………………………………………………………...for bicoloured brown

and phosphorescent strip.

- Dibutyl phthalate

- Epoxidised soya-bean oil

- Calcium stearate

- Polyvinyl chloride

- Zinc Sulphide

6.2 Incompatibilities

None known.

6.3 Shelf life

Shelf life of the veterinary medicinal product as packaged for sale: 2 years

6.4 Special precautions for storage

Do not remove the collar from the pack until ready-to-use.

Do not store above 25 °C.

Protect from direct sunlight.

6.5 Nature and composition of immediate packaging

Collars of 24g, 39.2g and 41g impregnated PVC strips.

Blister pack of two collars: pocket and lid in acrylonitrile/methyl acrylate/butadiene co-polymer on

backing card.

Sachet: paper/polyethylene/aluminium foil/polyethylene laminate.

Box containing one or two sachets of one collar.

Not all pack sizes may be marketed.

6.6 Special precautions for the disposal of unused veterinary medicinal product or waste

materials derived from the use of such products, if appropriate

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal

products should be disposed of in accordance with local requirements.

EXTREMELY DANGEROUS to fish and aquatic life. Do not contaminate ponds, waterways or

ditches with the product or empty packaging.

4

Revised: 17 December 2008

AN: 00737/2008

7. MARKETING AUTHORISATION HOLDER

Virbac S.A.

1’ere Avenue – 2065 m

L.I.D.

06516 Carros Cedex

France

8. MARKETING AUTHORISATION NUMBER

Vm 05653 / 4095

9. DATE OF FIRST AUTHORISATION

Date: 23 January 2000

10. DATE OF REVISION OF THE TEXT

Date: December 2008

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