Consumer Medicine Information
What is in this leaflet
This leaflet answers some common
questions about TRUSAMIDE. It
does not contain all the available
It does not take the place of talking to
your doctor or pharmacist.
All medicines have risks and
benefits. Your doctor has
weighed the risks of you using
TRUSAMIDE against the benefits
they expect it will have for you.
If you have any concerns about
using this medicine, ask your
doctor or pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
What it is used for
TRUSAMIDE is used to lower
raised pressure in the eye and to
treat glaucoma. Glaucoma is a
condition in which the pressure of
fluid in the eye may be high.
However, some people with
glaucoma may have normal eye
pressure. Also, some people with
raised eye pressure may not have
Glaucoma is caused by a build-up
of the fluid which flows through
the eye. This build-up occurs
because the fluid drains out of
your eye more slowly than it is
being pumped in. Since new fluid
continues to enter the eye, joining
the fluid already there, the
pressure continues to rise. This
raised pressure may damage the
back of the eye resulting in
gradual loss of sight. Damage can
progress so slowly that the person
is not aware of this gradual loss of
Sometimes even normal eye pressure
is associated with damage to the back
of the eye.
There are usually no symptoms of
glaucoma. The only way of knowing
that you have glaucoma is to have
your eye pressure, optic nerve and
visual field checked by an eye
specialist or optometrist. If
glaucoma is not treated it can lead to
serious problems. You may have no
symptoms but eventually glaucoma
can lead to total blindness. In fact,
untreated glaucoma is one of the
most common causes of blindness.
Although TRUSAMIDE helps
control your glaucoma it does not
For more information about
glaucoma, contact Glaucoma
Australia Inc., PO Box 420, Crows
Nest 1585, telephone 02 9906 6640.
TRUSAMIDE is used, either alone
or in combination with other eye
drops or medicines, to lower raised
pressure within your eye(s).
TRUSAMIDE lowers pressure in the
eye by reducing the production of
TRUSAMIDE belongs to a family of
medicines called carbonic anhydrase
TRUSAMIDE is not addictive.
Before you use it
When you must not use it
Do not use TRUSAMIDE if:
you have an allergy to
TRUSAMIDE or any of
the ingredients listed at the
end of this leaflet
you are breast-feeding
or intend to breast-feed
It is not known whether
TRUSAMIDE passes into
Do not put the eye drops into
your eye(s) while you are
wearing soft contact lenses.
The preservative in TRUSAMIDE
(benzalkonium chloride) may be
deposited in soft contact lenses.
You can put your soft contact
lenses back into your eyes at least
15 minutes after you have used
Do not use TRUSAMIDE if:
the seal around the cap
the bottle shows signs
the expiry date on the pack
If you use this medicine after the
expiry date has passed, it may not
If you are not sure whether you
should start using TRUSAMIDE,
talk to your doctor.
Do not give TRUSAMIDE to a
The safety and effectiveness of
TRUSAMIDE in children have not
Before you start to use it
Tell your doctor if:
you are pregnant or
intend to become pregnant
Your doctor will discuss the risks
and benefits of using
TRUSAMIDE during pregnancy
and a decision can be made if you
should or should not use it.
you have now or have had
in the past any medical
conditions, especially the
you have an allergy to
The active ingredient of
hydrochloride, is a sulfonamide-
related compound. Therefore, if you
are allergic to sulfonamide
medicines you may be allergic to
TRUSAMIDE. Check with your
doctor or pharmacist if you are not
sure whether you are allergic to
you have any allergies to
any other medicines or any
other substances, such as foods,
preservatives or dyes.
If you have not told your
doctor about any of the above,
tell them before you use
Taking other medicines
Tell your doctor if you are using
any other medicines or eye drops,
including medicines that you buy
without a prescription from your
pharmacy, supermarket or health
Some medicines and TRUSAMIDE
may interfere with each other. These
tablets used to treat glaucoma
large amounts of aspirin
These medicines may be affected by
TRUSAMIDE, or may affect how
well it works. You may need
different amounts of your medicine,
or you may need to take different
Your doctor or pharmacist has more
information on medicines to be
careful with or avoid while using
How to use it
How much to use
Your doctor will tell you how many
drops you need to use each day.
Use TRUSAMIDE only
when prescribed by your
When TRUSAMIDE is used alone,
the usual dose for adults is one drop
three times a day, in either one or
If your doctor has recommended that
you use TRUSAMIDE with a beta-
blocker eye drop, then the usual dose
for adults is one drop of
TRUSAMIDE twice a day, in either
one or both eyes.
Follow all directions given to you
by your doctor carefully.
They may differ from the
information contained in this leaflet.
After using TRUSAMIDE, wait at
least 10 minutes before putting any
other eye drops in your eye(s).
When to use it
If you are using TRUSAMIDE three
times a day, use the drops first thing
in the morning, in the early afternoon
and at bedtime (i.e. approximately 8
hours apart). If you are using
TRUSAMIDE twice a day, use the
drops in the morning and in the
evening (i.e. approximately 12 hours
Use TRUSAMIDE every day, at
about the same time each day,
unless your doctor tells you
Using your eye drops at the same
time each day will have the best
effect on your eye pressure. It will
also help you remember when to use
the eye drops.
How to use it
You may find it easier to put drops in
your eye while you are sitting or
Before opening the bottle for the
first time, make sure the two safety
seals joining the cap to the bottle
are not broken. If they are, do not
use the bottle and return it to your
You will notice a small space
between the cap and the bottle -
this is normal.
If you are wearing soft contact
lenses, remove them before
putting the drops in your eye.
Wash your hands well with
soap and water.
To open the bottle for the
first time, hold the bottle upright
and turn the cap in the direction of
the arrows until you can lift it off.
This will break the two safety
Place the cap upside down
(arrows face down) on a flat
surface. Do not touch the inside
of the cap. This will help keep the
inside of the cap clean and keep
germs out of the eye drops.
Hold the bottle upside down
in one hand, with your thumb or
index finger over the "finger push"
Using your other hand,
gently pull down your lower
eyelid to form a pouch.
Tilt your head back and look
Put the tip of the bottle close
to your lower eyelid. Do not let it
touch your eye.
Release one drop into the
pouch formed between your eye
and eyelid by gently squeezing the
Close your eye and keep it
closed. Do not blink or rub your
While your eye is still closed,
place your index finger against the
inside corner of your eye and press
against your nose for about two
This will help to stop the medicine
from draining through the tear
duct to the nose and throat, from
where it can be absorbed into
other parts of your body. Ask
your doctor for more specific
instructions on this technique.
Replace the cap, sealing it
tightly. Do not overtighten the
Wash your hands again with
soap and water to remove any
Wait at least 15 minutes before
replacing your contact lenses.
Be careful not to touch the dropper
tip against your eye, eyelid or
anything else to avoid
contaminating the eye drops.
Contaminated eye drops may give
you an eye infection.
You may feel a slight burning
sensation in the eye shortly after
using the eye drops.
If this persists, or is very
uncomfortable, contact your
doctor or pharmacist.
How long to use it
TRUSAMIDE helps control your
condition but does not cure it.
Therefore TRUSAMIDE must be
used every day. Continue using
TRUSAMIDE for as long as your
If you forget to use it
If it is almost time for your next
dose, skip the dose you missed and
use your next dose when you are
meant to. Otherwise, use the drops
as soon as you remember, and then
go back to using them as you would
If you are not sure whether to skip
the dose, talk to your doctor or
Do not use double the amount to
make up for the dose that you
If you have trouble remembering
to use your eye drops, ask your
pharmacist for some hints.
If you use too much
If you think that you or anyone
else may have swallowed any or all
of the contents of a bottle of
TRUSAMIDE, or used too many
drops, immediately telephone your
doctor or Poisons Information
Centre (telephone 13 11 26) for
advice, or go to accident and
emergency at your nearest
hospital. Do this even if there are
no signs of discomfort or
While you are using
Things you must do
Have your eye pressure checked
when your eye specialist says, to
make sure TRUSAMIDE is
If you develop an eye infection,
receive an eye injury, or have eye
surgery tell your doctor.
Your doctor may tell you to use a
new container of TRUSAMIDE
because of possible contamination of
the old one, or may advise you to stop
your treatment with TRUSAMIDE.
If you become pregnant while
using TRUSAMIDE tell your
If you are about to be started on
any new medicine tell your doctor
and pharmacist that you are using
Things you must not do
Do not give TRUSAMIDE to
anyone else, even if they have the
same condition as you.
Do not stop using
TRUSAMIDE without first
talking to your doctor.
If you stop using your eye drops,
your eye pressures may rise again
and damage to your eye may occur.
Things to be careful of
Be careful driving or operating
machinery until you know how
TRUSAMIDE affects you.
TRUSAMIDE generally does not
cause any problems with your ability
to drive a car or operate machinery.
However, it may cause certain side
effects in some people, including
blurred vision and dizziness. Make
sure you know how you react to
TRUSAMIDE before you drive a car
or operate machinery.
Tell your doctor or pharmacist
as soon as possible if you do not
feel well while you are using
TRUSAMIDE helps most people
with high eye pressure and
glaucoma, but it may have
unwanted side effects in a few
people. All medicines can have
side effects. Sometimes they are
serious, most of the time they are
not. You may need medical
treatment if you get some of the
Ask your doctor or pharmacist
to answer any questions you
Tell your doctor if you notice
any of the following and they
eye problems such as burning,
stinging, itching, conjunctivitis,
watering of the eye(s), redness of
the eye(s), swelling or crusting of
the eyelids(s), eye pain, blurred
bitter taste, dry mouth
numbness or tingling in fingers
These are usually mild side effects of
If any of the following happen,
stop using TRUSAMIDE and tell
your doctor immediately or go to
accident and emergency at your
wheezing, difficulty in
breathing, shortness of breath
swelling of the face, lips, mouth,
tongue or throat which may
cause difficulty in breathing or
severe and sudden onset of
pinkish, itchy swellings on
the skin, also called hives or
skin rash, itchiness
These may be serious side effects.
You may have an allergic reaction to
TRUSAMIDE. You may need
urgent medical attention. Serious
side effects are rare.
Other side effects not listed above
may also occur in some patients.
Tell your doctor if you notice any
Do not be alarmed by this list of
possible side effects. You may not
experience any of them.
After using it
Keep your eye drops in a cool dry
place where the temperature stays
Do not store it or any other
medicine in the bathroom or near a
Do not leave it in the car or on
Do not carry the eye drops in
pockets of your clothes.
Heat and dampness can destroy some
Keep the eye drops away from
Keep it where children cannot
A locked cupboard at least one-and-
a-half metres above the ground is a
good place to store medicines.
Do not leave the cap off the bottle
for any length of time to avoid
contaminating the eye drops.
Write the date on the bottle when
you open the eye drops and throw
out any remaining solution after
TRUSAMIDE contains a
preservative which helps prevent
germs growing in the solution for
the first four weeks after opening the
bottle. After this time there is a
greater risk that the drops may
become contaminated and cause an
eye infection. A new bottle should
If your doctor tells you to stop using
the eye drops or they have passed
their expiry date, ask your
pharmacist what to do with any
What does it look like
TRUSAMIDE comes as eye drops
in a 5 mL bottle.
equivalent to dorzolamide 2%
benzalkonium chloride as
TRUSAMIDE is supplied in
Aspen Pharma Pty Ltd
34-36 Chandos Street
St Leonards NSW 2065
This leaflet was prepared in March
Australian Register Numbers:
TRUSAMIDE - AUST R 217251