TILT

Main information

  • Trade name:
  • TILT 250 EC SYSTEMIC FUNGICIDE
  • Pharmaceutical form:
  • Emulsifiable
  • Units in package:
  • 1L, 5L, 10L, 20L, 50L, 90L, 100L,110L, 200L, 1000L
  • Class:
  • AgChem
  • Medicine domain:
  • Equipment
  • Medicine type:
  • Agrochemical
  • Manufactured by:
  • SYNGENTA AUST

Documents

Localization

  • Available in:
  • TILT 250 EC SYSTEMIC FUNGICIDE
    Australia
  • Language:
  • English

Therapeutic information

  • Therapeutic group:
  • APRICOT | BANANA | BARLEY | BORONIA | OATS | PEANUT | PEPPERMINT - OIL PRODUCTION ONLY | PERENNIAL RYEGRASS CROP | PINEAPPLE | P
  • Therapeutic area:
  • Group 3 Fungicide
  • Therapeutic indications:
  • BARLEY LEAF SCALD | BASE OR BUTT ROT - T. PARADOXA | BLACK SIGATOKA | BLIND SEED DISEASE | BLOSSOM BLIGHT - MONILINIA FRUCTICOLA | BLOSSOM BLIGHT - MONILINIA LAXA | CORDANA LEAF SPOT - CORDANA JOHNSTONII | CORDANA LEAF SPOT - CORDANA MUSAE | CROWN RUST (PUCCINIA CORONATA) ON OATS | EARLY LEAF SPOT ON PEANUT | LATE LEAF SPOT ON PEANUT | LEAF RUST | LEAF SMUT ON POPPY | LEAF SPECKLE ON BANANA | LEAF SPOT OR YELLOW SIGATOKA ON BANANA | NET FORM OF NET BLOTCH | PINEAPPLE DISEASE | POWDERY MILDEW - BULMERIA GRAMINIS | PRUNE RUST | RUST ON BORONIA | RUST ON MINT | RUST ON PEANUT | SEPTORIA LEAF BLOTCH - SUPPESSION | SEPTORIA NODORUM BLOTCH ON WHEAT | SEPTORIA TRITICI BLOTCH | SPOT FORM NET BLOTCH - PYRENOPHORA TERES | STEM RUST | YELLOW LEAF SPOT ON WHEAT | YELLOW OR STRIPE RUST | BARLEY SCALD | BROWN ROT | BUTT ROT | CERATOCYSTIS PARADOXA | PEANUT RUST | PUCCINIA RECONDITA F.SP. TRITI | PUCCINIA STRIIFORMIS | PUCCINIA TRITICINA | SEPTORIA TRITICI | SIGATOKA | WHEAT LEAF RUST | YELLOW RUST | YELLOW SIGATOKA | YELLO
  • Product summary:
  • Controls certain fungal diseases of bananas, oats, peanuts, perennial ryegrass, pineapples, stone fruit, sugarcane, wheat and other crops.Cereals: DO NOT apply more than 2 applications of TILT (or any other group C fungicide) in any one season on the same paddock.

Other information

Status

  • Source:
  • Australian Pesticides and Veterinary Medicines Authority (APVMA)
  • Authorization status:
  • Registered and available
  • Authorization number:
  • 30490/54129
  • Authorization date:
  • 22-11-2011
  • Last update:
  • 15-06-2017

Patient Information leaflet: composition, indications, side effects, dosage, interactions, adverse reactions, pregnancy, lactation

Tilt 250 EC Systemic Fungicide

Version: 2

Page 1

Pack sizes: 5, 20, 100, 110, 1000

August

2011

POISON

KEEP OUT

REACH OF CHILDREN

READ SAFETY DIRECTIONS BEFORE OPENING OR USING

Tilt®

Systemic

Fungicide

ACTIVE CONSTITUENT:

PROPICONAZOLE

SOLVENT:

LIQUID HYDROCARBON

GROUP

FUNGICIDE

Controls certain fungal diseases

Bananas, Oats, Peanuts,

Perennial Ryegrass, Pineapples, Stone Fruit, Sugarcane, Wheat

other crops

certain States as specified

the Directions for

IMPORTANT: Read

attached

booklet

before use

5, 20, 100, 110

1000 LITRES

Syngenta

Crop Protection

Limited

Leve/1, 2-4 Lyonpark Road, Macquarie Park

2113

In a

transport

emergency

dial

000,

Police

Fire

Brigade

specialist

advice

emergency

only, ca/11800 033

hours)

APVMA

Approval

30490

54129

Item

number

Approved

Infopest

Verified

Tilt

Systemic Fungicide

Pack

sizes:

1000

DIRECTIONS FOR USE

Restraints:

Version: 2

Page

2 of 8

August

2011

Cereals:

DO NOT apply more than 2 applications of TILT (or any other Group C fungicide)

any one season

the same paddock.

f TILT

t d

t . .

1cat1ons

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unq1c1

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eren

1on.

Rate

Crop

Disease

State

WHP

Critical

Comments

hectare

High

volume

Apricots

Prune Rust

SA only

Dilute

spraying

1 day

This

subject

anti-resistance

(Tranzschelia

ml/100

strategy

discolor)

Apply by dilute or concentrate spraying

Concentrate

equipment. Apply the same amount

product

spraying

the target crop whether applying this

Refer

product

dilute or concentrate spraying

Mixing/

methods.

Application

Curative

Control:

Apply when the disease

section

first occurs. Further applications should

made when the disease occurs

growth.

NOT make more than 5

applications to any individual tree during the

season.

Protective

Treatment: Spray mancozeb or

zineb mixed with TILT 250 EC at the full

recommended rates of application.

Bananas

Leaf Spot

Ground

1 day

This

subject

a DMI anti-resistance

(including

(Mycosphaerella

Qld,

Application

strategy

bananas

musicola),

200 to 400 mL

Ground

application: Apply by misting

interplanted

Leaf Speckle

only

plus 3 to 5 L

machine or airblast sprayer. Use rates towards

with

(Mycosphaerel/a

water miscible oil,

the higher end of the range where weather

avocados)

musae),

a convenient

conditions favour diseases or where

Cordana Leaf

volume of water

equipment or terrain does not

rmit thorough

Spot

Aerial

Application

spray coverage of all foliage.

(Cord

400 mL

Sth Qld, NSW:

Ground

and aerial

johnstonii)

plus 3

application:

Commence spraying at the start

water miscible oil,

the sumll)er rainy season. Apply a

a minimum

maximum of 5

Group 3 .

sprays per season.

water

Apply a maximum

2 consecutive sprays

TILT 250

day intervals before

Aerial

Application

applying further treatments of a protectant

without

water

fungicide from a different activity group.

400 mL

Nth Qld, WA, NT:

Ground

and aerial

plus

application:

Commence spraying at the start

spraying oil

the wet season. Apply a regular schedule

{This use does not

protectant sprays. When the disease potential

require further

is high, apply a maximum

2 consecutive

dilution with water)

sprays

TILT 250

at 14 to

Leaf Spot

Ground

intervals before applying further treatments

a protectant fungicide from a different activity

(Mycosphaerel/a

Application

group. Apply a maximum of 6

Group 3

sprays

musico/a),

400 mL

per season. Continue with treatments using

Leaf Speckle

only

plus 3

alternative protectant fungicide for the

(Mycosphaerel/a

water miscible oil,

remainder

the season. Use the lower rate

musae),

a convenient

Nth Qld.

NOT apply during July,

Cordana Leaf

volume

water

August, September and October.

Spot

Aerial

Application

(Cordana

400 mL

musae)

plus 3 to 5 L

Black Sigatoka

Qld,

water miscible oil,

(Mycosphaerella

a minimum

fijiensis var

only

water

difformis)

Aerial

Application

without

water

400 mL

plus 8 to

L of

spraying

(This use does not

require further

dilution with water)

Tilt

Systemic Fungicide

Version: 2

Page

3 of 8

Pack

sizes: 5,

1000

August

2011

Rate

Crop

Disease

State

WHP

Critical Comments

Per

hectare

High volume

Barley

Powdery Mildew

500 mL

Harvest

Spray at the first sign of the disease during the

(8/umeria

States

4 weeks

tillering stage. A repeat spray

to 28 days

graminis)

Grazing

later may be required. Ensure thorough

Barley Scald

500 mL

7 days

coverage

stems and leaves.

Powdery Mildew:

Higher rates provide longer

(Rhynchosporium

protection.

secalis

Blotch-

500 mL

Apply from jointing (Z30) and before

Spot form

significant infecti

averages 10%

the flag-

(Pyrenophora

2 leaf. Ensure thorough coverage

stems

teres

and leaves. Use higher rates under high

maculata)

infection pressure or when longer residual

Net form

protection

required . Lower rates are

effective under low disease pressure but have

(Pyrenophora

reduced residual effect. Two applications of

teres

teres

the lower rate 14 to 28 days apart will

generally provide better control than a single

application at the higher rate. When conditions

are particularly favourable, the net form

disease can be particularly aggressive and the

higher rate only should

used under these

conditions.

Boronia

Rust

Tas,

500 mL

Apply 2 to 5 applications at 10

(Puccinia

intervals during the main disease period. Use

boroniae)

only

the lower rate when application

made

protectively before disease occurs. Use the

higher rate when the disease

first observed

and when the minimum number of

applications are applied.

Oats

Stem Rust

500 mL

Harvest

Apply at the first sign

disease and before

(Puccinia

States

4 weeks

there

an average

over 2 pustules per

graminis

Grazing

tiller.

Ensur

thorough coverage of stems and

venae)

7 days

leaves.

Crown Rust

250 to 500 mL

Apply after flag blade leaf

fully emerged or

(Puccinia

Z39 and before disease levels reach 1% of

coronata

flag leaf area. Consider control if disease

venae)

greater than 5

any lower leaf layer.

Use higher rates under high infection pressure

or when longer residual protection

required.

Lower rates are effective under low disease

pressure but have reduced residual effect.

Ensure thorough coverage.

Suppression

Apply after flag blade leaf

fully emerged or

Septoria Leaf

Z39 if infection averages 10% on the flag-2

Blotch

leaf. The high rate of application gives a

(Leptosphaeria

longer period

protection than the lower

avenaria)

rates. Use higher rates

high potential crops

when conditions favour severe disease

development during flowering. Lower rates are

effective under low disease pressure but have

reduced residual effect. Ensure thorough

coverage.

Peanuts

Early Leaf Spot

400 to 600 mL

14 days

This use

is

subject to a

OMI

anti-resistance

(Cercospora

Qld,

strategy.

arachidico/a),

NSW,

Spray when disease symptoms are first

Late Leaf Spot

observed. Apply at 14 day intervals while

(Cercosporidium

only

weather conditions favour disease. Use rates

persona tum)

towards the higher end

the range when wet

conditions prevail.

Use a fungicide from a different activity group

Rust

Sth Qld

600 mL

(non-OM I) after 3 consecutive sprays using

(Puccinia

only

TILT 250 EC alone. Apply a maximum

arachidis)

sprays per season. The leaves

peanuts

sprayed may become darker green

colour

and modified

shape. These effects will not

adversely affect yield at recommended rates.

Tilt 250

Systemic Fungicide

Version: 2

Page 4 of 8

Pack

sizes:

1000

August

2011

Rate

Crop

Disease

State

WHP

Critical

Comments

hectare

High

volume

Peppermint

Mint Rust

NSW,

500 mL

5 weeks

Apply 2 to 5 applications at 10

14 day

Spearmint

(Puccinia

Vic,

intervals during the main disease period.

grown for oil

menthae)

DO NOT use

mint

grown

fresh

production

only

only

market.

Perennial

Stem Rust

4 weeks

Apply at ear emergence and again at

Ryegrass

(Puccinia

only

anthesis.

graminis),

Blind Seed

Disease

(Gioeotinia

granigena)

Plums

Prune Rust

NSW,

Dilute

spraying

1 day

This

subject

a DMI

anti-resistance

for prune

(Tranzsche/ia

Vic, SA

mL/100 L

strategy.

production

discolor)

only

Apply by dilute or concentrate spraying

Concentrate

equipment.

Apply the same amount

spraying

product to the target crop whether applying

Refer

this product by dilute or concentrate spraying

Mixing/

methods.

Application

Curative

Control:

Apply when the disease

section

first occurs. Further applications should

made when the disease occurs

growth. DO NOT make more than 5

applications

any individual tree during the

season.

Protective

Treatment: Spray mancozeb or

zineb mixed with TILT 250 EC at the full

recommended rates

application.

Pineapples

Base Rot

Qld, NT

20 mL/100

Preplant

dip:

Ensure thorough coverage by

(Thie/aviopsis

only

totally immersing the planting material

paradoxa)

dip solution. Allow 50 mL of the dip solution

per plant. Apply the higher rate under

conditions

high disease pressure.

Poppies

Leaf Smut

500 mL

4 weeks

Usage recommended by poppy contract-

Papaver

(En tyloma

only

companies. Apply

mid season application

somniferum

fuse urn)

the full flower/petal drop period when

disease

present.

Stone

Fruit

Brown Rot

Vic,

Dilute

spraying

1 day

This

use is

subject

a DMI

anti-resistance

(Blossom Blight)

Tas,

25 mL/100 L

strategy.

(blossom phase)

Apply by dilute or concentrate spraying

(Moni/inia taxa)

only

Concentrate

equipment. Apply the same amount

product

Brown Rot

Qld,

spraying

to the target crop whether applying this

Refer to the

product by dilute or concentrate spraying

(blossom

phase)

NSW,

Mixing/

methods.

(Monilinia

Tas,

Application

Apply at early

0%) blossom and again

fructico/a)

section

at full bloom. A further application

made at

shuck-fall. Only 2 consecutive applications of

only

DMI fungicides can

made during this

period.

Brown Rot

Qld,

Apply by dilute or concentrate spraying

(fruit

NSW,

equipment. Apply the same amount

product

(Monilinia

Vic,

to the target crop whether applying this

Tas,

product by dilute

or concentrate spraying

fructicola)

methods.

Apply 3 weeks and 1 week before harvest.

only

Only 2 consecutive applications

fungicides can

made during this period.

The last Blossom Blight spray and the first

Brown Rot (fruit phase) spray should be

regarded

consecutive applications.

For varieties with extended harvesting

periods, a third spray during the picking period

may be applied if conditions are favourable for

disease development.

Tilt 250

Systemic Fungicide

Version: 2

Page 5 of 8

Pack sizes:

100,

110, 1000

August

2011

Rate

Crop

Disease

State

WHP

Critical Comments

Per hectare

High volume

Sugarcane

Pineapple

Qld,

20 mL/100 L

Ensure thorough coverage

the cut ends

disease

NSW,

sugar cane setts.

(Ceratocystis

paradoxa)

only

Wheat

Stripe Rust

Qld,

500 mL

Harvest

Spray between jointing and end

flowering

(Puccinia

NSW,

4weeks

when 10 to 20%

leaves are infected. A

striiformis)

Vic,

Grazing

repeat spray

to 28 days later may be

7 days

required. Use higher rate under high infection

pressure

where longer residual protection is

only

required.

Spray when 10 to 20% of leaves are infected.

only

A repeat spray

to 28 days later may

required. Use the higher rate under high

infection pressure

when longer residual

protection is required.

Powdery Mildew

150 to 500 mL

Spray at the first sign

the disease during the

(8/umeria

States

tillering stage. A repeat spray

to 28 days

graminis)

later may be required. Ensure thorough

coverage

stems and leaves. Higher rates

provide longer protection.

Stem Rust

500 mL

Apply at the first sign

disease and before

(Puccini

there are more than 2 pustules per tiller.

graminis)

Ensure thorough coverage

stems and

leaves.

Septoria Tritici

250 to 500 mL

Apply once between 70% flag leaf emergence

Blotch

and early flowering. Use the higher rate under

(Mycosphaerella

high infection pressure or where longer

graminicola)

residual protection is required.

Leaf Rust

150 to 500 mL

Apply after flag leaf is 70% emerged and

(Puccinia

before disease levels reach 1% of flag leaf

recondita f.sp.

area. Consider control if disease

greater

tritici; Puccinia

than 5 to 10% on any lower leaf layer. Use

triticina)

higher rates under high infection pressure

when longer residual protection

required.

Lower rates are effective under low disease

pressure but have reduced residual effect.

Ensure thorough coverage.

Septaria

Nodorum

Apply after flag leaves are around 70%

Blotch

emerged

infection averages 10% on the

(Phaeosphaeria

flag-2 leaf. The high rate

application gives a

longer period

protection than the lower

nodorum)

rates. Use higher rates on high potential crops

when conditions favour severe disease

development during flowering. Lower rates are

effective under low disease pressure but have

reduced residual effect. Ensure thorough

coverage.

Yellow Spot

250 to 500 mL

Apply once between 70% flag leaf emergence

(Pyrenophora

and early flowering. Use the higher rate under

tritici-repentis)

high infection pressure or where longer

residual protection is required. Apply after

70% flag leaf emergence and before disease

levels reach 5% on flag leaf. Higher rates give

longer residual protection and often better

economic returns.

NOT TO BE USED FOR ANY PURPOSE, OR

IN

ANY MANNER, CONTRARY TO THIS LABEL UNLESS

AUTHORISED UNDER APPROPRIATE LEGISLATION.

Tilt 250 EC Systemic Fungicide

Pack sizes:

20, 100, 110, 1000 L)

WITHHOLDING PERIODS

Peppermint, Spearmint:

Barley, Oats, Poppies, Wheat:

Peanuts:

Bananas,

Stone

Fruit:

Perennial Ryegrass:

Forage

fodder

Barley, Oats, Wheat:

Pineapple, Sugarcane:

GENERAL INSTRUCTIONS

Versi

Page 6

August

2011

DO NOT HARVEST FOR 5 WEEKS AFTER APPLICATION

DO NOT HARVEST FOR 4 WEEKS AFTER APPLICATION

DO NOT HARVEST FOR 14 DAYS AFTER APPLICATION

DO NOT HARVEST FOR 1 DAY AFTER APPLICATION

DO NOT GRAZE OR CUT FOR STOCK FOOD FOR 4

WEEKS AFTER APPLICATION

DO NOT GRAZE OR CUT FOR STOCK FOOD FOR 7 DAYS

AFTER APPLICATION

WITHHOLDING PERIOD NOT REQUIRED

Wheat-

Stripe

rust-

susceptible

varieties:

Apply when 10% leaves infected.

Wheat-

Stripe

rust-

moderately

susceptible

varieties:

Apply when 15 to 20% leaves infected.

Mixing

Add the required amount directly to the spray tank and mix well.

Pineapples-

prep/ant

dip:

Add the required amount

TILT 250

directly to the dip and mix well. Avoid

excessive contamination

the dip with organic matter.

Application

Cereals:

applied by boom spray or aircraft. Ensure complete coverage

leaves and stems

obtained. The object of spraying

to keep the upper 2 to 3 leaves green and functioning through grain filling

stage.

With aircraft,

a guide, apply 10 to

L/ha with the lower rate being used when applications are made with a

cross wind of not less than 5 knots. Use the higher rates when applying to dense crops.

Apricots,

Plums

other

Stone Fruit: Apply by high volume (dilute) sprayer or by concentrate sprayer.

Dilute spraying

Use a sprayer designed to apply high volumes of water up to the point of runoff and matched to the crop being

sprayed. Set up and operate the sprayer to achieve even coverage throughout the crop canopy. Apply

sufficient water to cover the crop to the point

runoff. Avoid excessive runoff. The required water volume may

determined by applying different test volumes, using different settings

the sprayer, from industry

guidelines or expert advice.

the amount of product specified

the Direction for Use table for each 100 L

of water. Spray to the point of run-off. The required dilute spray volume will change and the sprayer set up and

operation may also need to

changed, as the crop grows.

Concentrate spraying

Use a sprayer designed and set up for concentrate spraying (that

a sprayer which applies water volumes

less than those required to reach the point

runoff) and matched to the crop being sprayed. Set up and

operate the sprayer to achieve even coverage throughout the crop canopy using your chosen water volume.

Determine

appropriate dilute spray volume (see Dilute spraying above) for the crop canopy. This

needed

to calculate the concentrate mixing rate. The mixing rate for concentrate spraying can then

calculated

following way:

EXAMPLE ONLY

Dilute spray volume

determined above: for example 2000 L/ha

Your chosen concentrate spray volume: for example 500 Llha

The concentration factor

this example

: 4 x (ie, 2000 L

500 L

If the dilute label rate

then the concentrate rate becomes 4 x 25, that

00 L of

concentrate spray.

The chosen spray volume, amount

product per 100 L of water, and the sprayer set up and operation may

need to be changed

the crop grows. For further information

concentrate spraying, users are advised to

consult relevant industry guidelines, undertake appropriate competency training and follow industry Best

Practices.

Compatibility

TILT 250

compatible with many commonly used orchard sprays which includes Ridomil® Gold Plus and

some formulations of azinphos-methyl, demeton-s-methyl, diazinon, methomylliquid, propargite, parathion,

dimethoate, copper oxychloride, mancozeb, zineb and chlorothalonil. Mixtures with more than one

above are not recommended.

Tilt 250 EC Systemic Fungicide

Version: 2

Page 7 of 8

Pack sizes:

20, 100, 110, 1000 L)

August

2011

Fungicide

Resistance Warning

GROUP

FUNGICIDE

TILT 250

a member

the DMI group

fungicides. For fungicide resistance management TILT 250

a Group 3 fungicide. Some naturally occurring individual fungi resistant to TILT 250

and other Group 3

fungicides may exist through normal genetic variability

any fungal population. The resistant individuals can

eventually dominate the fungi population if these fungicides are used repeatedly. These resistant fungi will not

controlled by TILT 250

and other Group 3 fungicides, thus resulting

a reduction

efficacy and

possible yield loss. Since the occurrence

resistant fungi

difficult to detect prior to use, Syngenta Crop

Protection Pty Limited accepts

liability for any losses that may result from the failure of TILT 250

control resistant fungi.

PRECAUTION

Re-entry Period

DO NOT enter treated area until spray has dried.

PROTECTION OF WILDLIFE, FISH, CRUSTACEA AND ENVIRONMENT

DO NOT contaminate streams, rivers or waterways with the chemical or used containers.

PROTECTION

LIVESTOCK

Low hazard to bees. No special precautions are required.

STORAGE AND DISPOSAL

20 L

pack

sizes

Store

the closed, original container

a cool, well ventilated area. DO NOT store for prolonged periods

direct sunlight.

Triple or preferably pressure rinse containers before disposal. Add rinsings to spray tank. DO NOT dispose of undiluted

chemicals

site. For pineapples, dispose of spent dip

approved landfill, or bury under at least 500

soil

non-crop, non-pasture area away from water sources or homes. If recycling , replace cap and return clean containers to

recycler or designated collection point.

not recycling, break, crush, or puncture and bury empty containers

a local

authority landfill.

If no landfill is available, bury the containers below 500 mm

a disposal pit specifically marked and set

up for this purpose clear

waterways, desirable vegetation and tree roots. Empty containers and product should not be

burnt.

100, 110

1000 L

pack

sizes

Store in the closed, original container in a cool, well ventilated area. DO NOT store for prolonged periods

direct sunlight.

Empty contents fully into application equipment. Close all valves and return to point

supply for refill or storage. For

pineapples, dispose of spent dip

approved landfill, or bury under at least 500 mm of soil in a non-crop, non-pasture

area away from water sources or homes.

SAFETY DIRECTIONS

Harmful

swallowed

. Will damage

eyes.

Will

irritate

nose

throat

skin.

Avoid

contact

with

eyes and

skin.

DO NOT inhale vapour. When

opening

container

preparing

spray

wear:

cotton

overalls

buttoned

neck

wrist

washable

elbow

length

PVC,

nitrile

neoprene

gloves

goggles

disposable

fume

mask

covering

mouth

and nose.

When

using

prepared

spray

wear:

cotton

overalls

buttoned

neck

wrist

washable

elbow

length

PVC,

nitrile

neoprene

gloves

goggles

product

eyes,

wash

immediately

with

water

product

skin,

immediately

wash

area

with

soap

water.

Wash

hands

after

use.

After

each

day's

wash

gloves

goggles

contaminated

clothing.

FIRST AID

poisoning

occurs

contact

doctor

Poisons

Information

Centre.

Phone

126.

swallowed,

NOT induce vomiting. Give a gl

ater

MATERIAL SAFETY DATA SHEET

If additional hazard information

required refer to the Material Safety Data Sheet. For a copy phone 1800 067

108 or visit our website

www.syngenta.com

Tilt 250 EC Systemic Fungicide

Version: 2

Page 8 of 8

Pack sizes:

20, 100, 110, 1000 L)

August

2011

MANUFACTURER'S WARRANTY AND EXCLUSION OF LIABILITY

Syngenta has no control over storage, handling and manner of use

this product. Where this material

stored, handled or used correctly and

accordance with directions, no express or implied representations or

warranties concerning this product (other than non-excludable statutory warranties) will apply. Syngenta

accepts

liability for any loss or damage arising from incorrect storage, handling or use.

Product names marked

®or

™,

the ALLIANCE FRAME

the SYNGENTA Logo and the PURPOSE ICON

are Trademarks

a Syngenta Group Company

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Lupin Pharmaceuticals, Inc. Issues Voluntary Recall of Ceftriaxone for Injection USP, 250mg, 500mg, 1g and 2g

Lupin Pharmaceuticals, Inc. Issues Voluntary Recall of Ceftriaxone for Injection USP, 250mg, 500mg, 1g and 2g

Lupin Pharmaceuticals, Inc. is voluntarily recalling 5 lots of Ceftriaxone for Injection, USP, 250mg, 10 lots of Ceftriaxone for Injection, USP, 500mg, 24 lots of Ceftriaxone for Injection, USP, 1g and 3 lots of Ceftriaxone for Injection, USP 2g, to the hospital/physician level. The products have been found to contain visual grey particulate matter in reconstituted vials.

FDA - U.S. Food and Drug Administration

7-12-2018

Magnesium citrate malate as a source of magnesium added for nutritional purposes to food supplements

Magnesium citrate malate as a source of magnesium added for nutritional purposes to food supplements

Published on: Thu, 06 Dec 2018 The present scientific opinion deals with the assessment of the bioavailability of magnesium, from the proposed nutrient source, magnesium citrate malate (MgCM), when added for nutritional purposes to food supplements. MgCM is a mixed salt consisting of magnesium cations and citrate and malate anions, and with a magnesium content of 12–15%. MgCM is proposed to be used in food supplements that are intended to provide up to 300–540 mg/day magnesium. The data provided demonst...

Europe - EFSA - European Food Safety Authority Publications

3-8-2018

Scientific guideline:  Cholic acid capsules 50 mg and 250 mg product-specific bioequivalence guidance, adopted

Scientific guideline: Cholic acid capsules 50 mg and 250 mg product-specific bioequivalence guidance, adopted

Cholic acid capsules 50 mg and 250 mg product-specific bioequivalence guidance

Europe - EFSA - European Food Safety Authority EFSA Journal

31-7-2018

Public Notification: Black Rhino 25000 contains hidden drug ingredient

Public Notification: Black Rhino 25000 contains hidden drug ingredient

The Food and Drug Administration is advising consumers not to purchase or use Black Rhino 25000, a product promoted for sexual enhancement. This product was identified during an examination of international mail shipments.

FDA - U.S. Food and Drug Administration

31-7-2018

Public Notification: Krazzy Rhino 25000 contains hidden drug ingredient

Public Notification: Krazzy Rhino 25000 contains hidden drug ingredient

The Food and Drug Administration is advising consumers not to purchase or use Krazzy Rhino 25000, a product promoted for sexual enhancement. This product was identified during an examination of international mail shipments.

FDA - U.S. Food and Drug Administration

31-7-2018

Public Notification: Gold Rhino 25000 contains hidden drug ingredient

Public Notification: Gold Rhino 25000 contains hidden drug ingredient

The Food and Drug Administration is advising consumers not to purchase or use Gold Rhino 25000, a product promoted for sexual enhancement. This product was identified during an examination of international mail shipments.

FDA - U.S. Food and Drug Administration

31-7-2018

Public Notification: Platinum Rhino 25000 contains hidden drug ingredient

Public Notification: Platinum Rhino 25000 contains hidden drug ingredient

The Food and Drug Administration is advising consumers not to purchase or use Platinum Rhino 25000, a product promoted for sexual enhancement. This product was identified during an examination of international mail shipments.

FDA - U.S. Food and Drug Administration

10-7-2018

Preventieve HIV-remmers (PrEP) worden verstrekt voor een periode van vijf jaar

Preventieve HIV-remmers (PrEP) worden verstrekt voor een periode van vijf jaar

PrEP wordt binnen een onderzoekssetting voor een periode van vijf jaar verstrekt aan de hoogrisicogroep van mannen die seks hebben met mannen (MSM). Dat heeft minister Bruno Bruins (Medische Zorg) vandaag bekend gemaakt. Op basis van schattingen van het RIVM zullen ongeveer 6500 mannen hiervan gebruik gaan maken en kunnen hiermee  250 hiv-infecties per jaar worden voorkomen. Voor gebruikers gaat een eigen bijdrage gelden van maximaal 25%, dat komt overeen met ongeveer 12 euro per maand. Ook wordt hen gev...

Netherlands - Ministerie van Volksgezondheid, Welzijn en Sport

4-5-2018

Badger Botanicals Recalls Red Suma, Green Suma, Green Hulu 2, And Red Hulu 2 Kratom Supplements Because Of Possible Salmonella Health Risk

Badger Botanicals Recalls Red Suma, Green Suma, Green Hulu 2, And Red Hulu 2 Kratom Supplements Because Of Possible Salmonella Health Risk

Badger Botanicals, LLC of Springville, Utah is recalling Green Suma, Red Suma, Green Hulu 2, and Red Hulu 2 kratom dietary supplements sold directly to consumers via the company website from January 1st, 2018 to April l 12th, 2018 in pouches of 250g, because it has the potential to be contaminated with Salmonella.

FDA - U.S. Food and Drug Administration

15-1-2014

Revocation of wholesale distribution and manufacturing authorisations granted to Singad Pharma ApS

Revocation of wholesale distribution and manufacturing authorisations granted to Singad Pharma ApS

On 20 December 2013 and on 10 January 2014, the Danish Health and Medicines Authority decided to revoke the section 39 authorisations for wholesale distribution and manufacturing of medicinal products with the authorisation IDs 25081 and 25082 granted to Singad Pharma ApS (company number 255894).

Danish Medicines Agency

10-12-2018

EU/3/17/1906 (PTC Therapeutics International Limited)

EU/3/17/1906 (PTC Therapeutics International Limited)

EU/3/17/1906 (Active substance: Recombinant adeno-associated viral vector serotype 5 carrying the gene for the human frataxin protein) - Transfer of orphan designation - Commission Decision (2018)8634 of Mon, 10 Dec 2018 European Medicines Agency (EMA) procedure number: EMA/OD/0000002509

Europe -DG Health and Food Safety

10-12-2018

EU/3/16/1786 (PTC Therapeutics International Limited)

EU/3/16/1786 (PTC Therapeutics International Limited)

EU/3/16/1786 (Active substance: Recombinant adeno-associated viral vector serotype 2 carrying the gene for the human aromatic L-amino acid decarboxylase protein) - Transfer of orphan designation - Commission Decision (2018)8630 of Mon, 10 Dec 2018 European Medicines Agency (EMA) procedure number: EMA/OD/0000002507

Europe -DG Health and Food Safety

10-12-2018

EU/3/16/1651 (PTC Therapeutics International Limited)

EU/3/16/1651 (PTC Therapeutics International Limited)

EU/3/16/1651 (Active substance: Recombinant adeno-associated viral vector serotype 9 carrying the gene for the human E6-AP ubiquitin protein ligase) - Transfer of orphan designation - Commission Decision (2018)8632 of Mon, 10 Dec 2018 European Medicines Agency (EMA) procedure number: EMA/OD/0000002508

Europe -DG Health and Food Safety

28-11-2018

PHEBURANE (Eurocept International BV)

PHEBURANE (Eurocept International BV)

PHEBURANE (Active substance: Sodium Phenylbutyrate) - Centralised - Transfer Marketing Authorisation Holder - Commission Decision (2018)8043 of Wed, 28 Nov 2018 European Medicines Agency (EMA) procedure number: EMEA/H/C/2500/T/20

Europe -DG Health and Food Safety

30-10-2018

EU/3/14/1250 (Akcea Therapeutics UK Ltd)

EU/3/14/1250 (Akcea Therapeutics UK Ltd)

EU/3/14/1250 (Active substance: Phosphorothioate oligonucleotide targeted to transthyretin) - Transfer of orphan designation - Commission Decision (2018)7282 of Tue, 30 Oct 2018 European Medicines Agency (EMA) procedure number: EMA/OD/098/13/T/01

Europe -DG Health and Food Safety

29-10-2018

Replagal (Shire Human Genetic Therapies AB)

Replagal (Shire Human Genetic Therapies AB)

Replagal (Active substance: Agalsidase alfa) - Centralised - Yearly update - Commission Decision (2018)7250 of Mon, 29 Oct 2018

Europe -DG Health and Food Safety

3-7-2018

Samsca (Otsuka Pharmaceutical Europe Ltd)

Samsca (Otsuka Pharmaceutical Europe Ltd)

Samsca (Active substance: tolvaptan) - Centralised - 2-Monthly update - Commission Decision (2018) 4250 of Tue, 03 Jul 2018 European Medicines Agency (EMA) procedure number: EMEA/H/C/980/II/31

Europe -DG Health and Food Safety

6-6-2018

Stocrin (Merck Sharp and Dohme B.V.)

Stocrin (Merck Sharp and Dohme B.V.)

Stocrin (Active substance: efavirenz) - Centralised - Transfer Marketing Authorisation Holder - Commission Decision (2018)3689 of Wed, 06 Jun 2018 European Medicines Agency (EMA) procedure number: EMEA/H/C/250/T/113

Europe -DG Health and Food Safety

23-4-2018

Mylotarg (Pfizer Limited)

Mylotarg (Pfizer Limited)

Mylotarg (Active substance: gemtuzumab ozogamicin) - New authorisation - Commission Decision (2018)2504 of Mon, 23 Apr 2018 European Medicines Agency (EMA) procedure number: EMEA/H/C/4204

Europe -DG Health and Food Safety