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Seven

Main information

  • Trade name:
  • Seven Seas Kitzyme 15% w/w Flea Rid Reflective Flea Collar
  • Available from:
  • Virbac S.A.
  • Medicine domain:
  • Animals
  • Medicine type:
  • Allopathic drug
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Documents

Localization

  • Available in:
  • Seven Seas Kitzyme 15% w/w Flea Rid Reflective Flea Collar
    United Kingdom
  • Language:
  • English

Other information

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Status

  • Source:
  • VMD - Veterinary Medicines Directorate
  • Authorization status:
  • Expired
  • Authorization number:
  • 05653/4098
  • Last update:
  • 21-12-2016

Summary of Product characteristics

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Revised: 24 August 2010

AN: 02270/2008

SUMMARY OF PRODUCT CHARACTERISTICS

1. NAME OF THE VETERINARY MEDICINAL PRODUCT

Seven Seas Kitzyme 15% w/w Flea Rid Reflective Flea Collar

2. QUALITATIVE AND QUANTITATIVE COMPOSITION

Active ingredient

Dimpylate

Each 14g collar contains

2.1 g of dimpylate

15 % w/w

Excipients

Flash Black 19976 0.026 % w/w for black collar

Flash Black 19976

Red Ferric oxide (E172) 0.0087 % w/w for brown collar

0.035 % w/w for brown collar

Ariabel Scarlet

Lithol Rubine K4566

Lithol Rubine K4566 0.5 % w/w for red collar

0.1 % w/w for red collar

0.001 % w/w for pink collar

Flash Beige 40232

Flash Blue 47949

Titanium Dioxide (E171)

Titanium Dioxide (E171)

Titanium Dioxide (E171)

Titanium Dioxide (E171)

Quinoline Yellow Certolake (E104)

Flash Yellow 47948 0.3 % w/w for beige collar

0.16 % w/w for blue collar

0.15 % w/w for white collar

0.45 % w/w for pink collar

0.1 % w/w for green collar

0.12 % w/w for yellow collar

0.48 % w/w for yellow collar

0.3 % w/w for yellow collar

Tartrazine Lake (E102)

Blue Alphazurine Lake 0.28 % w/w for green collar

0.12 % w/w for green collar

Matrix:

On the active strip, a reflecting band may be stuck.

3. PHARMACEUTICAL FORM

Collar

Black or brown or beige or red or blue or green or yellow or pink or white supple

plastic trip provided with a buckle and with a characteristic odour.

4. CLINICAL PARTICULARS

4.1 Target Species

Cats

1

Revised: 24 August 2010

AN: 02270/2008

4.2 Indications for use

For the control of fleas on cats for up to 4 months

4.3 Contra-indications

Do not use on kittens under 6 months of age

4.4 Special warnings for each target species

Do not allow animals to chew the collar.

Fleas from pets often infest animals’ basket, bedding and regular resting areas

such as carpets and soft furnishings which should be treated with a suitable

insecticide and vacuumed regularly.

4.5 Special precautions for use

i. Special precautions for use in animals

Do not use if your cat is sick or recovering from an illness.

ii. User warnings

Do not allow children to play with the collar.

Do not allow children to suck or chew the collar.

Do not smoke, eat or drink while handling collar.

DO NOT SLEEP WITH PETS WEARING FLEA COLLARS.

Dimpylate is an organophosphorus compound: DO NOT handle if under

medical advice not to work with ANTICHOLINESTERASES.

IF YOU FEEL UNWELL AFTER HANDLING THE COLLAR, SEEK MEDICAL

ADVICE.

Wash hands thoroughly after handling the collar.

4.6 Adverse reactions (frequency and seriousness)

A slight irritation on the neck may occasionally occur.

Remove collar immediately should any signs of skin irritation or adverse reaction

occur

REMOVE COLLAR FROM CAT IMMEDIATELY SHOULD ANY SIGNS OF

DROWSINESS, LISTLESSNESS OR RESPIRATORY DIFFICULTIES DEVELOP

SOON AFTER FIXING OF COLLAR.

4.7 Use during pregnancy, lactation or lay

Not for use on nursing or lactating queens.

Remove fleas from young kittens and nursing queens by careful use of a flea

comb.

2

Revised: 24 August 2010

AN: 02270/2008

4.8 Interaction with other medicinal products and other forms of Interaction

Do not use any other insecticides while the collar is being worn or within 7 days of

removal.

4.9 Amounts to be administrated and administration route

Insecticidal Collar for cats weighing 14 g and 35 cm in length

Remove collar from sachet and fasten around the cat’s neck adjusting until a

comfortable fit is achieved. In the fully grown cat, correct fitting will allow one

finger to be inserted between the collar and the neck. Any excess length of collar

extending beyond the buckle should be cut off and disposed of with the domestic

refuse. Leave in place until the collar’s effective life is exhausted. Replace after 4

months if re-infestation with fleas is a risk.

4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary

Dimpylate is an organophosphorus compound and atropine is antidotal.

Signs of overdosage include drowsiness, listlessness or respiratory difficulty.

4.11 Withdrawal Period

Not applicable

5. PHARMACOLOGICAL PROPERTIES

ATC VetCode: QP53AF15

Collar for cats contains Dimpylate as a parasiticide.

5.1 Pharmacodynamic properties

Dimpylate, an organophosphorus parasiticide is active against common fleas

(Ctenocephalides) of cats. It acts mainly by inhibiting insect enzymes such as

cholinesterases. This is achieved when Dimpylate competes with acetylcholine,

responsible for nerve impulses, by binding to the esterase site of the

cholinesterase molecules.

Acetylcholine, degraded at a lower pace, accumulates and induces disorders.

Because the metabolism of Dimpylate in insects is very slow, irreversible poisoning

is achieved.

In mammals, cholinesterase activity similarly decreases. However, this is only

transitory since enzyme synthesis is resumed and dimpylate is degraded within a

very short period of time.

Dimpylate being slowly released from the collar’s matrix, the product remains

active for up to 4 months.

3

Revised: 24 August 2010

AN: 02270/2008

6. PHARMACEUTICAL PARTICULARS

6.1 List of excipients

Flash Black 19976

Red Ferric oxide (E172)

Ariabel Scarlet

Lithol Rubine K4566

Flash Beige 40232

Tartrazine Lake (E102)

Blue Alphazurine Lake

Titanium Dioxide (E171)

Flash Blue 47949

Quinoline Yellow Certolake (E104)

Flash Yellow 47948

Dibutyl Phthalate

Epoxidised Soyabean Oil

Calcium Stearate

Polyvinyl Chloride

6.2 Incompatibilities

None Known

6.3 Shelf life

Shelf life of the veterinary medicinal product as packaged for sale: 2 years

6.4 Special precautions for storage

Do not store above 25°C.

Protect from direct sunlight.

Do not remove collar from the pack until ready-to-use.

6.5 Nature and composition of immediate packaging

Blister pack: pocket and lid in acrylonitrile / methyl acrylate / butadiene co-polymer.

Strip-pack: paper / polyethylene / aluminium foil / polyethylene laminate.

Twin pack presentations containing 2 blister packs or 2 strip packs.

Not all pack sizes may be marketed

6.6 Special precautions for the disposal of unused veterinary medicinal

products or waste materials derived from the use of such products

Any unused veterinary medicinal product or waste materials derived from such

veterinary medicinal products should be disposed of in accordance with local

requirements.

EXTREMELY DANGEROUS to fish and aquatic life. Do not contaminate ponds,

waterways or ditches with the product or empty container.

4

Revised: 24 August 2010

AN: 02270/2008

7. MARKETING AUTHORISATION HOLDER

VIRBAC S.A.

1ère avenue - 2065 m - L.I.D.

06516 Carros Cedex

FRANCE

8. MARKETING AUTHORISATION NUMBER

Vm 05653/4098

9. DATE OF FIRST AUTHORISATION

23/01/2000

10. DATE OF REVISION OF THE TEXT

August 2010

5

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