Pigzin

Main information

  • Trade name:
  • Pigzin Premix for Medicated Feedingstuff
  • Pharmaceutical form:
  • Premix for medicated feed
  • Medicine domain:
  • Animals
  • Medicine type:
  • Allopathic drug

Documents

Localization

  • Available in:
  • Pigzin Premix for Medicated Feedingstuff
    Ireland
  • Language:
  • English

Therapeutic information

  • Therapeutic group:
  • zinc oxide
  • Therapeutic area:
  • Pigs Food

Status

  • Source:
  • HMA - Europe
  • Authorization number:
  • UK/V/0487/001
  • Authorization date:
  • 13-12-2012
  • EU code:
  • UK/V/0487/001
  • Last update:
  • 09-08-2016

Summary of Product characteristics: dosage, interactions, side effects

Revised:May2013

AN:00905/2012

SUMMARYOFPRODUCTCHARACTERISTICS

1. NAMEOFTHEVETERINARYMEDICINALPRODUCT

PigzinPremix,100% w

Premixformedicatedfeedingstuff

2. QUALITATIVEANDQUANTITATIVECOMPOSITION

Qualitativecomposition

ZincOxide

Forfulllistofexcipientsseesection

6.1 Quantitativecomposition

100% w

/

w

3. PHARMACEUTICALFORM

Premixformedicatedfeedingstuff

Asoft,whiteorfaintlyyellowishwhiteamorphouspowder.

4. CLINICALPARTICULARS

4.1 Targetspecies

Pigsupto10weeksofage

4.2 Indicationsforuse,specifyingthetargetspecies

Forthetreatmentandcontrolofdiarrhoeainpigs

4.3 Contraindications

Noneknown

4.4 Specialwarningsforeachtargetspecies

Noneknown

4.5 Specialprecautionsforuse

i.Specialprecautionsforuseinanimals

Noneknown

ii.Specialprecautionsforthepersonadministeringtheveterinary

medicinalproducttoanimals

Revised:May2013

AN:00905/2012

Weareitheradisposablehalf-maskrespiratorconformingto

EuropeanStandardEN149oranon-disposablerespiratorto

EuropeanStandardEN140withafiltertoEN143whenmixingor

handlingthefeed.

Avoidcontactwiththeskinbywearingprotectiveclothing,including

impermeablegloves.Incaseofaccidentalskincontact,washthe

exposedskinwithsoapandwater.

Avoidcontactwiththeeyesbywearingprotectivegogglesorsafety

glasses.Incaseofaccidentaleyecontactirrigatethoroughlywith

largequantitiesofwater.

Contaminatedclothingshouldberemovedandwashedbefore

beingreused.

Incaseofaccidentalingestion,drinkplentyofwaterandseek

medicalattention.

Washhandsafteruse.

iii.

Otherprecautions

Noneknown

4.6 Adversereactions(frequencyandseriousness)

Noneknown

4.7 Useduringpregnancy,lactationorlay

Notapplicable

4.8 Interactionwithothermedicinalproductsandotherformsof

interaction

Noneknown

4.9 Amount(s)tobeadministeredandadministrationroute

Fororaladministrationonly

Forincorporationintodryfeedataregistered/licensedmill.Formore

information:

IntheUKrefertoVMGNNo3,GuidanceforRetailers,

Revised:May2013

AN:00905/2012

InIrelandseekadvicefromtheDepartmentofAgriculture,Food

andtheMarine.

Administer2900-3100mg/kgPigzinPremix(whichprovides2320-2489

mg/kgelementalzinc)sothattheamountofzincalreadypresentinthe

feed(naturallyoccurringzincplusaddednutritionalzinc)istakenaccount

oftoensurethatthefinalfeedcontains2500mg/kgofelementalzinc.

Toensureadequatedistributionoftheproductinthefinalfeeditis

recommendedthatitbepremixedwithasuitablequantityoffeed

ingredientsbeforeblendingintothefinalfeed.Thefinalfeedshouldbe

fedastheonlyfeedforupto14days.

4.10 Overdose(symptoms,emergencyprocedures,antidotes),if

necessary

Noknownproblems.

4.11 Withdrawalperiod(s)

Animalsmustnotbeslaughteredforhumanconsumptionduring

treatment.Animalsmaybeslaughteredforhumanconsumptiononlyafter

28daysaftertheendoftreatment.

5. PHARMACOLOGICALPROPERTIES

Pharmacotherapeuticgroup:

Anti-diarrhoeal

ATCVetCode:QA07XA91

5.1 Pharmacodynamicproperties

Themodeofactionofzincoxideinthetreatmentandcontrolofdiarrhoea

hasnotbeendetermined.Ithasbeenshowntohaveafavourableeffect

onthegutmicroflorabyhelpingtopreventthereductionindiversityof

microflorathatoccurredintheintestinesofcontrolpigsduringthesecond

weekafterweaning.

5.2 Pharmacokineticproperties

Absorption –Zincisanessentialtraceelementforlivestockrequiredfor

themaintenanceofdailybodilyfunction.Zincoxideisknowntobe

relativelypoorlyabsorbedandtherapeuticlevelshaveincreasedblood

levelsbyafactoroftwo.

Distribution –Therapeuticlevelsofzincoxidefedforfourweeksafter

weaninghavebeenshowntoincreasezinclevelsintheliverandkidney

Revised:May2013

AN:00905/2012

ofpigsbyafactorofapproximatelyfiveandtworespectively.No

increasesinmusclelevelswerenoted.

Biotransformation –Zincisatraceelementessentialfordailymetabolism

inthebody.Sincetherapeuticlevelsarepoorlyabsorbed,itisbelieved

thatmostisvoidedunchangedinthefaeces.

Elimination –Mostzincfromzincoxideisexcretedwithoutabsorption.

6. PHARMACEUTICALPARTICULARS

6.1 Listofexcipients

None

6.2 Incompatibilities

Noneknown

6.3 Shelflife

Shelflifeoftheveterinarymedicinalproductaspackagedforsale:2

Years.

Shelflifeafterincorporationintomealorpelletedfeed:3Months

6.4 Specialprecautionsforstorage

Storeinacleandryplace.Donotstoreabove25°C

Storeintightlyclosedoriginalcontainer.

Storeawayfromfood,drinkandanimalfeedingstuffs

Closethebagsecurelyafteruse.

Theshelflifeafterincorporationintofeedisthreemonths.

6.5 Natureandcompositionofimmediatepackaging

Three-plypapersackscontaining25kgofasoft,whiteoryellowishwhite

amorphouspowder.

Sacksarefilledviaasidevalve,whichistuckedinandgluedtoforma

closure.

6.6 Specialprecautionsforthedisposalofunusedveterinarymedicinal

productorwastematerialsderivedfromtheuseofsuchproducts,if

appropriate

Anyunusedveterinarymedicinalproductorwastematerialsderivedfrom

suchveterinarymedicinalproductsshouldbedisposedofinaccordance

withlocalrequirements.

Revised:May2013

AN:00905/2012

7. MARKETINGAUTHORISATIONHOLDER

DSMNutritionalProducts(UK)Limited

DelvesRoad

HeanorGateIndustrialEstate

Heanor

Derbyshire

DE757SG

8. MARKETINGAUTHORISATIONNUMBER

Vm19108/4000

9. DATEOFFIRSTAUTHORISATION

05May2000

10. DATEOFREVISIONOFTHETEXT

May2013

Approved: 17/05/2013