Country: United Kingdom
Language: English
Source: VMD (Veterinary Medicines Directorate)
Dinoprost
Norbrook Laboratories Limited
QG02AD01
Dinoprost
Solution for injection
POM-V - Prescription Only Medicine – Veterinarian
Cattle
Prostaglandin
Expired
1996-01-09
Revised: 16 th December 2008 AN: 02406/2007 1. NAME OF THE VETERINARY MEDICINAL PRODUCT Noroprost 0.5 % w/v Solution for Injection. 2. QUALITATIVE AND QUANTITATIVE COMPOSITION ACTIVE SUBSTANCE: Each ml of product contains 5 mg (0.5% w/v) of Dinoprost (Prostaglandin F 2 ), EXCIPIENTS: 2.5 mg (0.25% w/v) Phenol as antimicrobial preservative. For a full list of excipients, see section 6.1 3. PHARMACEUTICAL FORM Solution for injection. Clear, colourless solution. 4. CLINICAL PARTICULARS 4.1 TARGET SPECIES Cattle 4.2 INDICATIONS FOR USE, SPECIFYING THE TARGET SPECIES Noroprost is indicated for its luteolytic effect on corpora lutea in cattle. This luteolytic action of Noroprost may be utilised as follows: 1. To improve control of the time of oestrus in cycling cattle. 2. To control breeding in cattle. 3. To induce parturition in cattle. 4. Synchronisation of recipient cattle for embryo transplantation. 5. To induce abortion in cattle. 6. To treat cattle which have a functional corpus luteum but do not express behavioural oestrus (sub-oestrus or silent heat). 7. For treatment of chronic metritis and pyometra in cattle. 8. For treatment of ovarian luteal cysts. Revised: 16 th December 2008 AN: 02406/2007 4.3 CONTRAINDICATIONS Do not administer by the intravenous route. Animals should not be treated if they suffer from either acute or sub acute disorders of the vascular system, gastrointestinal tract or respiratory system. 4.4 SPECIAL WARNINGS FOR EACH TARGET SPECIES No special warnings. 4.5 SPECIAL PRECAUTIONS FOR USE SPECIAL PRECAUTIONS FOR USE IN ANIMALS Noroprost is ineffective when administered prior to day 5 after ovulation. Observe aseptic precautions during use. SPECIAL PRECAUTIONS TO BE TAKEN BY THE PERSON ADMINISTERING THE VETERINARY MEDICINAL PRODUCT TO ANIMALS Prostaglandins of the F 2 type can be absorbed through the skin and MAY CAUSE BRONCHOSPASM OR MISCARRIAGE. Care should be taken when handling the product to AVOID SELF-INJECTION OR SKIN CONTACT. In case of accidental self-injection, seek medical Read the complete document