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Memocal

Main information

  • Trade name:
  • Memocal 40 CM Solution for Injection
  • Medicine domain:
  • Animals
  • Medicine type:
  • Allopathic drug
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Documents

Localization

  • Available in:
  • Memocal 40 CM Solution for Injection
    United Kingdom
  • Language:
  • English

Other information

Status

  • Source:
  • VMD - Veterinary Medicines Directorate
  • Authorization status:
  • Expired
  • Authorization number:
  • 41687/4010
  • Last update:
  • 21-12-2016

Summary of Product characteristics

Revised: October 2012

AN: 00838/2012

SUMMARY OF PRODUCTS CHARACTERISTICS

1. NAME OF THE VETERINARY MEDICINAL PRODUCT

Memocal 40 CM Solution for Injection

2. QUALITATIVE AND QUANTITATIVE COMPOSITION

Active Substance:

Calcium Borogluconate 40% CM contains Calcium Borogluconate 40% w/v 

and Magnesium Hypophosphite Hexahydrate 5% w/v.

Each 400ml contains:

11.9g calcium (provided by calcium gluconate and calcium borogluconate) 

and 

1.85g magnesium (provided by magnesium hypophosphite).

Also contains 6.48% w/v Boric Acid

Excipients:

For a full list of excipients, see section 6.1

3.  PHARMACEUTICAL FORM

Solution for injection

A clear pale yellow solution

4.  CLINICAL PARTICULARS

4.1  Target species

Cattle

4.2  Indications for use, specifying the target species

Memocal 40 CM Solution for Injection is indicated in the treatment of 

hypocalcaemia in cattle where increased blood magnesium levels are 

required

4.3  Contraindications

None

4.4  Special Warnings for each target species

None

Page 1 of 4

Revised: October 2012

AN: 00838/2012

4.5      Special precautions for use

Special precautions for use in animals

The solution should be warmed to body temperature before 

administration. Intravenous injections should be given slowly in 

order to avoid possible neuromuscular dysfunction and cardiac 

insufficiency. Normal aseptic precautions should be observed. 

Sites of subcutaneous administration should be massaged gently.

ii.    Special precautions to be taken by the person administering the 

veterinary medicinal product to animals

Care should be taken to avoid accidental self injection; may cause 

irritation at the site of injection.

4.6     Adverse reactions (frequency and seriousness)

Occasional temporary swelling may occurs at sites of subcutaneous 

administration 

4.7     Use during pregnancy, lactation or lay

Memocal 40 CM Solution for Injection is safe for use during pregnancy 

and lactation.

4.8     Interaction with other medicinal products and other forms of 

interaction

None

4.9     Amounts to be administered and administration route

Administer by subcutaneous or slow intravenous injection

Cattle: 200 - 400ml

4.10   Overdose (symptoms, emergency procedures, antidotes), if 

necessary

Not applicable

4.11   Withdrawal period

Meat: Zero days

Milk: Zero days

Page 2 of 4

Revised: October 2012

AN: 00838/2012

5.      PHARMACOLOGICAL PROPERTIES

Pharmacotherapeutic group: Calcium, combinations with other drugs

ATCVet code: QA12A

5.1    Pharmacodynamic properties

Calcium Borogluconate and Magnesium Hypophosphite are soluble 

salts of calcium and magnesium respectively used extensively in fluid 

infusions in correction of metabolic disturbances. On parenteral 

administration they rapidly increase plasma concentrations of calcium, 

magnesium and phosphorus. This is effective in the treatment of 

hypocalcaemia with associated magnesium and phosphorus 

deficiencies.

6.       PHARMACEUTICAL PARTICULARS

6.1     List of excipients

Boric acid or Sodium Bicarbonate for pH adjustment

Water for injections

6.2     Incompatibilities

None Known

6.3     Shelf life

Shelf life of the veterinary medicinal product as packaged for sale: 

Glass bottles: 2 years

Polyproprylene vials: 18 months

6.4     Special precautions for storage

Do not store above 25°C. Protect from light.

This product does not contain an antimicrobial preservative. Any 

solution remaining in the vial following withdrawal of the required dose 

should be discarded.

6.5     Nature and composition of immediate packaging 

Memocal 40 CM Solution for Injection is marketed in either 400 ml 

Amber Type III glass vials sealed using black rubber wads and 

aluminium screw caps, or 400 ml polypropylene containers sealed with 

bromobutyl bungs and aluminium caps.

Page 3 of 4

Revised: October 2012

AN: 00838/2012

6.6     Special precautions for the disposal of unused veterinary 

medicinal product or waste materials derived from the use of 

such products

Any unused veterinary medicinal product or waste materials derived 

from such veterinary medicinal products should be disposed of in 

accordance with local requirements.

7.       MARKETING AUTHORISATION HOLDER

Listow Limited

9 Belgrave Square

London

SW1X 8PH

8.       MARKETING AUTHORISATION NUMBER(S)

Vm

: 41687/4010

9.      DATE OF FIRST AUTHORIASATION

Date: 5 July 1999

10.    DATE OF REVISION OF THE TEXT

Date: October 2012

Page 4 of 4

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