Country: United Kingdom
Language: English
Source: VMD (Veterinary Medicines Directorate)
Isoflurane
Piramal Critical Care Limited
Isoflurane
Inhalation vapour, solution
POM-V - Prescription Only Medicine – Veterinarian
Cats, Dogs, Horses, Mouse, Ornamental Birds, Rabbits, Rat, Reptiles
Neurological Agent general anaesthetic
Authorized
1999-06-28
Revised: February 2022 AN: 01412/2021 Page 1 of 6 SUMMARY OF PRODUCT CHARACTERISTICS 1. NAME OF THE VETERINARY MEDICINAL PRODUCT Isofane 100% _wlw _Inhalation vapour, liquid. 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Active substance: Isoflurane 100% w/w For a full list of excipients, see section 6.1 3. PHARMACEUTICAL FORM Inhalation vapour, liquid A clear colourless liquid with a characteristic odour. 4. CLINICAL PARTICULARS Summary presentation of the active substance: Isoflurane is a volatile liquid halogenated hydrocarbon. Although the exact mode of action is poorly understood it is thought that, in common with other general anaesthetics, isoflurane acts by competing with endogenous ligands for binding to specific neuroreceptors. 4.1 TARGET SPECIES Horses, dogs, cats, small mammals, ornamental birds and reptiles. 4.2 INDICATIONS FOR USE, SPECIFYING THE TARGET SPECIES To induce and maintain anaesthesia in all types of veterinary surgery. 4.3 CONTRAINDICATIONS Do not use in animals sensitive to isoflurane or other halogenated or inhalation anaesthetic agents. Do not use in animals with a known susceptibility to malignant hyperthermia. 4.4 SPECIAL WARNINGS FOR EACH TARGET SPECIES Horses: Recovery from isoflurane anaesthesia is generally smooth and rapid. However, one report suggests that horses recovering from isoflurane anaesthesia may appear un-coordinated. It is important to provide adequate post-anaesthetic analgesia since isoflurane anaesthetised horses may become aware of their surroundings more rapidly than horses recovering from halothane anaesthesia. Other species: none Revised: February 2022 AN: 01412/2021 Page 2 of 6 4.5 SPECIAL PRECAUTIONS FOR USE i. Special precautions for use in animals None known ii. Special precautions for the person administering the veterinary medicinal product to animals Do not breathe the vapour. The Occupational Exposure Standard (OES) for isoflurane has been set at 50 ppm on an 8-hour weighted average. Operating rooms and recovery areas should be provided with adequate ve Read the complete document