Main information

  • Trade name:
  • CODESAN COMP oral solution
  • Pharmaceutical form:
  • oral solution
  • Prescription type:
  • Prescription only
  • Medicine domain:
  • Humans
  • Medicine type:
  • Allopathic drug



  • Available in:
  • CODESAN COMP oral solution
  • Language:
  • English

Therapeutic information

  • Therapeutic area:
  • Opium derivatives and expectorants
  • Product summary:
  • Suitability for use in older adult patients Cocillanae extractum fluidum There is a lack of research evidence, clinical experience or efficacy among older persons. Ephedrini hydrochloridum Avoid use in older persons. Do not use on patients with an ischaemic heart disease. Avoid use in severe renal or hepatic insufficiency. Significant adverse effects include insomnia, tremor, palpitations, elevated blood pressure and urinary retention. Take interactions into account. Codeini phosphas hemihydricus Suitable for older persons, with specific cautions. Slightly anticholinergic. Slightly sedative. A weak opioid which induces tolerance. Reduce the dose in even mild renal insufficiency. Avoid use in severe renal insufficiency. In some persons, the response is weaker or stronger than normal due to genetic differences. Take interactions into account, since many medicines reduce the efficacy of codeine. Start a laxative to prevent constipation. Diphenhydramini hydrochloridum Avoid use in older persons. Anticholinergic. Slightly sedative. Risk of QT prolongation. Significant adverse effects include constipation, urinary retention, cognitive disorder and arrhythmias. Take interactions into account.


  • Source:
  • Fimea
  • Authorization status:
  • Marketing authorization granted
  • Authorization number:
  • 3449
  • Authorization date:
  • 07-09-2006
  • Last update:
  • 26-07-2018