CIFLOC 500 (tablets)
Country: South Africa
Language: English
Source: South African Health Products Regulatory Authority (SAHPRA)
Patient Information leaflet
(PIL)
16-04-2024
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Patient Information leaflet
CIFLOC 250 (tablets)
CIFLOC 500 (tablets)
CIFLOC 750 (tablets)
SCHEDULING STATUS:
S4
PROPRIETARY NAME
(and dosage form):
CIFLOC 250 (tablets)
CIFLOC 500 (tablets)
CIFLOC 750 (tablets)
COMPOSITION:
CIFLOC 250: Each tablet contains ciprofloxacin hydrochloride equivalent to 250 mg
ciprofloxacin
.
CIFLOC 500: Each tablet contains ciprofloxacin hydrochloride equivalent to 500 mg ciprofloxacin.
CIFLOC 750: Each tablet contains ciprofloxacin hydrochloride equivalent to 750 mg ciprofloxacin.
PHARMACOLOGICAL CLASSIFICATION:
A. 20.1.1. Broad and medium spectrum antibiotics.
PHARMACOLOGICAL ACTION
Ciprofloxacin is a synthetic, 4-quinolone derivative and inhibits gyrase-mediated DNA supercoiling.
It has in vitro bactericidal activity against the following Gram-negative and Gram-positive organisms. In vitro sensitivity
does not necessarily imply in vivo efficacy.
Acinetobacter
Haemophilus influenzae
Proteus vulgaris
Streptococcus pyogenes
Aeromonas
Haemophilus para-influenzae Providencia rettgeri
Streptococcus species
Brucella
Hafnia
Providencia stuartii
Vibrio
Campylobacter jejuni Klebsiella species
Pseudomonas aeruginosa
Viridans streptococci
Citrobacter freundii Listeria
Salmonella enteritidis
Yersinia
Citrobacter species
Moraxella catarrhalis
Serratia marcescens
Corynebacterium
Morganella morganii
Shigella flexneri
E. coli
Neisseria gonorrhoea
Shigella sonnei
Edwardsiella
Pasteurella
Staphylococcus aureus
Enterobacter cloacae Plesiomonas
Staphylococcus epidermidis
Enterobacter species Proteus mirabilis
Streptococcus faecalis
The following organisms show varying degrees of in vitro sensitivity to ciprofloxacin:
Alcaligenes, Enterococcus faecalis, Flavobacterium, Gardnerella, Legionella, Mycobacterium fortuitum,
Mycobacterium tuberculosis, Mycoplasma hominis, Streptococcus agalactiae, Chlamydia.
The following organisms are usually resistant:
Enterococcus
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