Chloramphenicol 0.5% Eye Drops
What is in this leaﬂet:
What Chloramphenicol Eye Drops are and what
they are used for
What you need to know before you use
Chloramphenicol Eye Drops
How to use Chloramphenicol Eye Drops
Possible side eﬀects
How to store Chloramphenicol Eye Drops
Contents of the pack and other information
1. What Chloramphenicol Eye Drops
are and what they are used for
Chloramphenicol belongs to a group of medicines
called antibiotics. An antibiotic is a medicine which
is used for the treatment of a variety of infections
caused by bacteria. Chloramphenicol Eye Drops
are used in both adults and children for the
treatment of a wide range of eye infections caused
2. What you need to know before you
use Chloramphenicol Eye Drops
Do not use Chloramphenicol Eye Drops if:
you are allergic to chloramphenicol or any of
the other ingredients of this medicine listed in
· you or someone in your family ever had a blood
disorder or bone marrow disease including
anemia (decrease in the number of red blood
cells) when using chloramphenicol in the past.
· you have a family history of “dyscrasias”, a
condition which can cause tiredness, bruising
and an increased risk of infections
Warnings and precautions
Talk to your doctor or pharmacist before using
Chloramphenicol Eye Drops if
· you have visual disturbances
· you have severe pain in the eye
· you are sensitive to light
· your eye is inﬂamed and you have a rash on the
scalp or face
· your eye looks cloudy
· your black or coloured part of the eye
· you have a foreign body in the eye
· you have an eye infection that keeps
· you have glaucoma (raised pressure in the eye)
· you have dry eyes
· you have eye injury or eye surgery
· you are currently using any other eye drops or
Take special care:
If you develop a new eye infection during this
treatment, you should stop using the drops and
speak to your doctor.
If you use chloramphenicol eye drops for a long
time, your doctor may do some blood tests to
check for any problems.
Other medicines and Chloramphenicol
Tell your doctor or pharmacist if you are using,
have recently used or might use any other
In particular, tell your doctor if you are taking any
of the following:
medicines for cancer such as methotrexate
medicines for the immune system such as
the dietary supplement chymotrypsin
Pregnancy and breast-feeding
Chloramphenicol should not be used during
pregnancy and breast-feeding unless considered
essential by your doctor, as the eﬀects are
unknown. If you are a pregnant or breast-feeding,
think you may be pregnant or are planning to
have a baby, ask your doctor or pharmacist for
advice before using this medicine.
Driving and using machines
Chloramphenicol Eye Drops can cause temporary
blurring of vision after application. Wait until your
vision is clear before driving or using machines.
Chloramphenicol eye drops contain
phenylmercuric nitrate as a preservative which
may cause allergic reaction. Do not wear contact
lenses during treatment.
3. How to use Chloramphenicol
Always use this medicine exactly as your doctor or
pharmacist has told you. Check with your doctor
or pharmacist if you are not sure.
Contact lenses should be taken out before
treatment with Chloramphenicol Eye Drops.
Instructions for use
Wash your hands well before use
Remove the outer cap. You may ﬁnd it easier to
apply your drops in front of a mirror.
Tilt the head back and pull the lower lid of the
eye out to form a pocket
Hold the container between the thumb and
middle ﬁnger of the other hand, turn the
container upside down near to the eye, try not
to touch the eye with the nozzle
Apply enough pressure to
the container to release one
to two drops
Blink the eye a few times
If you think that you have missed the eye, then
insert another drop
Repeat in the other eye if you have been told
to use Chloramphenicol Eye Drops in both eyes
Replace the outer cap on the container,
trying not to touch the applicator tip with
anything, including the eye or the ﬁngers
10. Wash your hands.
How much to use
One to two drops should be applied to each
aﬀected eye up to six times daily or more
frequently if required. Severe infections may
require one or two drops every ﬁfteen to twenty
minutes initially; reducing the frequency of use as
the infection is controlled.
Prolonged use of Chloramphenicol Eye Drops is
not advisable. You should not use this product for
longer than 5 days at a time unless your doctor has
told you otherwise.
Use in children:
Dosage adjustment may be necessary in newborn
infants to reduce the risk of adverse eﬀects. The
maximum duration of treatment is 10-14 days.
If you use more chloramphenicol than
Chloramphenicol Eye Drops are for external use
only. If you suspect someone has swallowed any
Chloramphenicol Eye Drops, contact your doctor
or go to the accident and emergency department
of your local hospital at once. Always take the
container with you, if possible, even if empty.
If you accidentaly apply too much drops, you
should wash your eye with plenty of water, if any
painful symptoms continue after this, you should
tell your doctor immediately.
If you forget to use Chloramphenicol
Try not to miss doses. If you do miss a dose, do not
worry, just carry on as normal. Do not use extra
drops to make up.
4. Possible side eﬀects
Like all medicines, this medicine can cause side
eﬀects, although not everyone gets them.
Stop using your medicine and tell your doctor
or pharmacist immediately if you experience the
following side eﬀects:
· Wheeziness (shortness of breath), fever, swelling
of your face, lips or tongue, itching or rash
with swelling of skin (the rash could be puﬀy
(swollen) or blotchy, or look like little blisters.
· A sore throat, bruising or being unable to
overcome an infection. On very rare occasions,
patients using chloramphenicol have had
changes in their blood cells causing severe
tiredness or easy bruising
Possible side eﬀects include:
inﬂammation of the skin (dermatitis).
Rare side eﬀects include:
damage to parts of the eye
bone marrow depression (a condition where the
marrow is unable to produce red blood
a reduced production and death of red blood
If you get any side eﬀects, talk to your doctor,
pharmacist or nurse. This includes any possible
side eﬀects not listed in this leaﬂet. You can
also report side eﬀects directly via the Yellow
Card Scheme: www.mhra.gov.uk/yellowcard. By
reporting side eﬀects you can help provide more
information on the safety of this medicine.
5. How to store Chloramphenicol
Keep out of the sight and reach of children.
Do not use Chloramphenicol Eye Drops after the
expiry date printed on the bottle label. The expiry
date refers to the last day of the month. Once you
have opened the bottle use within 4 weeks.
You are advised to dispose of the bottle once you
have ﬁnished your 5 day course of treatment.
This medicine needs to be stored upright between
2-8°C (in a refrigerator). Protect from light. Do not
allow it to freeze.
Medicines should not be disposed of via
wastewater or household waste. Ask your
pharmacist how to dispose of medicines no longer
required. These measures will help to protect the
6. Contents of the pack and other
What Chloramphenicol Eye Drops contains
The active ingredient is Chloramphenicol 0.5%
The other ingredients are Puriﬁed Water, Boric
Acid, Borax and Phenylmercuric Nitrate 0.002%
What Chloramphenicol Eye Drops look like
and contents of the pack
Chloramphenicol Eye Drops are supplied in plastic
bottles, each bottle containing 10ml of sterile
Marketing Authorisation Holder:
Martindale Pharmaceuticals Ltd.
Bampton Road, Romford, RM3 8UG, England
63.Ag Dimitriou str.
17456 Alimos, Athens
If you would like any more information, or
would like the leaﬂet in a diﬀerent format,
please contact Medical Information at the
Product Licence Numbers:
HK – 09064
This leaﬂet was last updated February 2017
Read all of this leaﬂet carefully before you use start using this medicine because it
contains important information for you.
Keep this leaﬂet. You may need to read it again
If you have any further questions, please ask your doctor or pharmacist
This medicine has been prescribed for you only. Do not pass it on to others. It may harm them,
even if their signs of illness are the same as yours
If you get any side eﬀects, talk to your doctor or pharmacist. This includes any possible side
eﬀects not listed in this leaﬂet. See section 4
PACKAGE LEAFLET: INFORMATION FOR THE USER
100mm Measurement Veriﬁcation Bar