Information for the user
Chloramphenicol 0.5% w/v Eye Drops
Read all of this leaflet carefully because it contains important information for you.
This medicine is available without prescription to treat bacterial conjunctivitis. However, you
still need to use it carefully to get the best results from it.
Keep this leaflet, you may need to read it again
Ask your pharmacist if you need more information or advice
You must contact a pharmacist or doctor if your symptoms worsen at anytime, or do not
improve after 48 hours
What this medicine is for
This medicine contains chloramphenicol, an antibiotic, which acts to treat bacterial
It can be used for the treatment of acute bacterial conjunctivitis. Conjunctivitis is an infection
of the lining that covers the front of the eye. When you have bacterial conjunctivitis the white
part of one or both of your eyes will be red and/or your eyelids will be red and swollen.
There will be a sticky discharge from the eye, which may make it hard to open your eye
when you wake up, and your eye may feel “gritty” or “irritated”.
These eye drops are not suitable for treating serious eye infections (see “!Talk to your
Before you use this medicine
This medicine can be used by adults and children aged 2 years and over. However, some
people should not use this medicine or should seek the advice of their pharmacist or doctor
Do not use:
If you are allergic to chloramphenicol or any of the ingredients
If you have ever had problems with your bone marrow or blood when using
chloramphenicol in the past (this includes capsules, injections and eye drops) – your doctor
will have told you this
If you have a family history of blood “dyscrasias” – a condition which can cause
problems such as tiredness, fatigue, unusual bruising, or an increase in the number of
infections that you get
If you are pregnant or breastfeeding, unless your doctor tells you to
Talk to your doctor:
If you have any of the following symptoms of a serious eye infection:
- your eyesight has been affected by the infection – you may have loss of sight, reduced
sight, blurred vision or see halos around lights
- you are sensitive to bright lights
- you have pain within the eye
- your eye looks cloudy or the pupil of your eye looks unusual
- your eye is swollen and you have rash on your face
You will need antibiotic tablets or injections to treat these infections.
You should also talk to your doctor:
If you have a foreign body (e.g. a splinter) in your eye which has not been removed
If you have an eye infection that keeps coming back often
If you have had eye surgery or laser treatment in the last six months
If you have raised pressure in the eye (glaucoma), dry eyes syndrome or an eye injury, or
you have had one of these before
If you are using any other eye drops or eye ointments
If you wear contact lenses – If your doctor tells you to use this medicine, see ‘Other
Other important information
Do not use this medicine for long periods of time or to treat an infection that keeps coming
back. If you do the infection may become resistant to this medicine and will be difficult to
treat if you get it again.
Driving and using machines: This medicine can cause blurred vision. Do not drive or use
machines until you are sure that you are not affected.
If you wear contact lenses: If your doctor or contact lens practitioner has advised you to
use this medicine do not wear your contact lenses during the course of treatment.
Wear your glasses instead.
If you wear soft contact lenses: The preservative in this medicine may damage them. Wait
for at least 24 hours after you last use the medicine before wearing your lenses again.
Information about some of the ingredients: Phenylmercuric nitrate may cause allergic
If you take other medicines
Before you use this medicine, make sure that you tell your pharmacist about any other
medicines you might be using at the same time, particularly the following:
Medicines that suppress your bone marrow such as drugs used to treat cancer
If you are unsure about interactions with any other medicines, talk to your pharmacist.
How to use this medicine
Check that the seal is not broken before first use. If it is do not use the drops.
For use in the eyes only.
Follow the directions below which show you how to put the drops into your eye.
How much to use
How often to use it
Adults and children of 2 years
Put one drop into the
If both eyes are infected put
one drop into each eye.
For the first 48 hours use
every 2 hours and then use
every 4 hours.
Use the medicine for 5 days. Do not stop using the medicine before then, even if you feel
better, because this could make your condition worse.
It is only necessary to use this medicine during the day when you are awake. You do not
need to wake yourself up in the night to use it.
If you forget to use the drops: Use them as soon as you remember, and then carry on as
normal. If it is almost time for the next dose, wait until the normal time. Never double up on
the dose to make up for the missed one.
If your symptoms do not begin to improve within 48 hours talk to your doctor.
If your symptoms worsen at any time during treatment see a doctor at once.
Do not use for children under 2 years.
Breathe on or touch the dropper nozzle
Touch the eyes or eyelids with dropper nozzle
Share you eye drops with anyone else
Wash and dry your hands
Open the bottle. Take care that the tip of the dropper bottle does not touch your eye, the
skin around your eye or your fingers.
3. Tilt your head backwards while seated, or lie down on your back
Place the tip of the bottle close to your eye. Gently pull the lower eye lid downwards and
Squeeze the bottle gently and let one drop fall into the space between the lower eye lid
and the eye
Close your eye for a moment
If both eyes are infected repeat steps 3 to 6 for the other eye
Replace the cap securely after use
Possible side effects
Most people can use this medicine without any problems but sometimes you may notice
some side effects.
If you notice any of the following serious side effects, stop using the medicine and
see your doctor at once.
Swelling of the lips, throat or face, difficulty breathing, a sore, red itchy or lumpy rash, fever –
these are symptoms of a severe allergic reaction
If you notice any of the following side effects, talk to your doctor or pharmacist:
Severe tiredness or easy bruising - this may be a sign of bone marrow depression
You may notice a temporary burning or stinging sensation when you put the drops in your
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any
possible side effects not listed in this leaflet. You can also report side effects directly via the
Yellow Card Scheme at: www.mhra.gov.uk/yellowcard. By reporting side effects you can
help provide more information on the safety of this medicine.
How to store this medicine
Store this medicine in a refrigerator between 2°C and 8°C. Store it in the original package to
protect it from light.
Keep this medicine in a safe place out of the sight and reach of children.
Do not use this medicine after the Use By date on the carton.
Throw away any medicine left at the end of the 5 day course.
What is in this medicine
These drops contain Chloramphenicol 0.5% w/v, which is the active ingredient.
As well as the active ingredient, these drops also contain purified water, boric acid, borax
and phenylmercuric nitrate.
The pack contains 10 ml of eye drops.
Who makes this medicine
MAH: BCM, Nottingham NG2 3AA
Manufacturer: Hamol Limited Nottingham NG90 2DB
Leaflet prepared January 2015
is a registered trademark.
PACK MOCK UP BOX
Product Name: Almus Chloramphenicol 0.5% w/v Eye Drops
Product Licence No: PL00014/5181R
Wording Ref: Draft Copy V2, draft issue 3, 02/11/11, AL0079/Lt2, Pharma Code 957
Status: Internally Approved
Pack details: White HDPE/LDPE bottle, white LDPE plug
Pack size: 10 ml
Version No: 1
Date issued: 13/01/2015
Reason for change: addition of Yellow Card warning