Country: United Kingdom
Language: English
Source: VMD (Veterinary Medicines Directorate)
Acepromazine
Novartis Animal Health UK Ltd
QN05AA04
Acepromazine
Expired
Revised: 27 June 2008 AN: 01920/2007 SUMMARY OF PRODUCT CHARACTERISTICS 1. NAME OF THE VETERINARY MEDICINAL PRODUCT ACP Tablets 25 mg 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Active substance: mg/tablet Acepromazine 25.0 (as Acepromazine maleate 33.85) For a full list of excipients, see section 6.1. 3. PHARMACEUTICAL FORM Tablet Pale yellow biconvex tablets, approximately 8 mm in diameter, scored on one side only. 4. CLINICAL PARTICULARS 4.1 TARGET SPECIES Dog and cat. 4.2 INDICATIONS FOR USE, SPECIFYING THE TARGET SPECIES _Anaesthetic premedication:_ Following acepromazine administration, the amount of anaesthetic dose necessary to induce anaesthesia is considerably reduced. This reduction is approximately one-third of a suitable induction agent. _Tranquillisation:_ Acepromazine tranquillisation (ataraxy) involves a modification of temperament which is not associated with hypnosis, narcosis, or marked sedation. This is achieved with low doses of acepromazine. _Sedation:_ At higher dose rates acepromazine is a sedative. _Travel Sickness:_ A dose of 1 mg per kg given orally a quarter to half an hour before a light meal is effective in the prevention of travel sickness. Idiopathic vomiting may be controlled by acepromazine. 4.3 CONTRAINDICATIONS Do not use in pregnant animals (see section 4.7). Do not use on a long term basis in individual animals. Revised: 27 June 2008 AN: 01920/2007 4.4 SPECIAL WARNINGS FOR EACH TARGET SPECIES There are no known additional special warnings. 4.5 SPECIAL PRECAUTIONS FOR USE I) SPECIAL PRECAUTIONS FOR USE IN ANIMALS Acepromazine is hypotensive. Particular care should therefore be taken in hypovolaemic subjects; rehydration should precede acepromazine administration. In some dogs, particularly Boxers and other short nosed breeds, spontaneous fainting or syncope may occur, due to sinoatrial block caused by excessive vagal tone, and an attack may be precipitated by acepromazine, so a low dose should be used. Where there is a history of this type of syncope, or if it is suspected bec Read the complete document