EQUIMAX 300 ORAL PASTE FOR FOALS, YEARLINGS AND PONIES

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

Buy It Now

Active ingredient:
ABAMECTIN; PRAZIQUANTEL
Available from:
VIRBAC (AUSTRALIA) PTY LTD
INN (International Name):
abamectin(3.7mg/g)+praziquantel(46.2mg/g)
Pharmaceutical form:
ORAL PASTE
Composition:
ABAMECTIN ANTHELMINTIC Active 3.7 mg/g; PRAZIQUANTEL ANTHELMINTIC Active 46.2 mg/g
Units in package:
16.2g Syr
Class:
VP - Veterinary Pesticide
Therapeutic group:
HORSE | COLT | DONKEY | ENDURANCE HORSE | FILLY | FOAL | GELDING | HIGH PERFORMANCE HORSES | HORSES AT STUD | MARE | PACER | POL
Therapeutic area:
PARASITICIDES
Therapeutic indications:
ASCARID - PARASACRIS EQUORIUM | BOTS - GASTEROPHILUS SPP. | DRASCHIA SPP. | HABRONEMA SPP. | INTESTINAL THREADWORM - S. WESTERI | LARGE MOUTH STOMACH WORM | LARGE STRONGYLES | LUNGWORM - DICTYOCAULUS ARNFIELDI | NECK THREADWORM | PINWORM - OXYURIS EQUI | ROUNDWORM | SMALL STRONGYLES | STOMACH HAIR WORM | TAPEWORM - ADULT/IMMATURE/HEADS/SEGMENTS | ANOPLOCEPHALA MAGNA | ANOPLOCEPHALA PERFOLIATA | BOT FLY | BOT FLY - ORAL AND GASTRIC STA | CORONOCYCLUS SPP. | CRATEROSTOMUM ACUTICAUDATUM | CUTANEOUS ONCHOCERCIASIS | CYALOCEPHALUS SPP. | CYATHOSTOMUM SPP. | CYLICOCYCLUS SPP. | CYLICODONTOPHORUS SPP. | CYLICOSTEPHANUS SPP. | CYLIOCOSTEPHANUS SPP. | CYLIOCYCLUS SPP. | GASTEROPHILUS HAEMORRHOIDALIS | GASTEROPHILUS INERMIS | GASTEROPHILUS INTESTINALIS | GASTEROPHILUS NASALIS | GASTEROPHILUS PECORUM | GYALOCEPHALUS SPP. | PARANOPLOCEPHALA MAMMILLANA | PARAPOTERIOSTOMUM SPP. | PETROVINEMA SPP. | POTERIOSTOMUM SPP. | STOMACH BOT | STRONGYLUS EDENTATUS | STRONGYLUS EQUINUS | STRONGYLUS VULGARIS | SUMMER SORES | TOXOCARA M
Product summary:
Poison schedule: 5; Withholding period: ; Host/pest details: HORSE: [ASCARID - PARASACRIS EQUORIUM, BOTS - GASTEROPHILUS SPP., DRASCHIA SPP., HABRONEMA SPP., INTESTINAL THREADWORM - S. WESTERI, LARGE MOUTH STOMACH WORM, LARGE STRONGYLES, LUNGWORM - DICTYOCAULUS ARNFIELDI, NECK THREADWORM, PINWORM - OXYURIS EQUI, ROUNDWORM, SMALL STRONGYLES, STOMACH HAIR WORM, TAPEWORM - ADULT/IMMATURE/HEADS/SEGMENTS]; For the treatment and control of tapeworms and roundworms (including arterial larval stages of Strongylus vulgaris and benzimidazole resistant small strongyles), bots, and skin lesions caused by Habronema and Drascia spp.(summer sores) and Onchocerca spp.
Authorization status:
Stopped
Authorization number:
52077
Authorization date:
2018-06-30

29 October, 1999

Intermediate – Syringe

Version #4

Page

1 of 3

____________________________________________________________________________________________________________

Infopest verifies that this label is consistent with the

NRA Approved Text Label of 12/8/99 ________

CAUTION (Red)

READ SAFETY DIRECTIONS BEFORE OPENING OR USING

KEEP OUT OF REACH OF CHILDREN (Red)

FOR ANIMAL TREATMENT ONLY

E

QUIMAX

®

300

O

RAL

P

ASTE FOR

F

OALS

, Y

EARLINGS AND

P

ONIES

ACTIVE CONSTITUENTS:

3.7 mg/g ABAMECTIN

46.2 mg/g PRAZIQUANTEL

For treatment and control of tapeworms and roundworms

(including arterial larval stages of Strongylus vulgaris and benzimidazole

resistant small strongyles), bots, and skin lesions caused by Habronema

and Draschia spp. (summer sores) and Onchocerca spp. microfilariae

(cutaneous onchocerciasis).

16.2 g

READ OUTER CARTON BEFORE USING THIS PRODUCT

DIRECTIONS FOR USE:

The contents of this syringe will treat one horse or pony at 300 kg bodyweight. Each weight marking

on the syringe plunger will deliver 5.4g (5mL) of paste which is sufficient to treat 100 kg bodyweight.

MEAT WITHHOLDING PERIOD:

DO NOT USE less than 28 days before slaughter for human consumption.

STORAGE:

Store below 30ºC (Room Temperature) away from light.

Registered Trade Mark of Virbac.

CODE: (Syringe)

EXP:

NRA: 52077/0799

29 October, 1999

Primary – Plastic Bucket or Cardboard Box

Version # 4

Page

2 of 3

____________________________________________________________________________________________________________

CAUTION (Red)

READ SAFETY DIRECTIONS BEFORE OPENING OR USING

KEEP OUT OF REACH OF CHILDREN (Red)

FOR ANIMAL TREATMENT ONLY

E

QUIMAX

®

300

O

RAL

P

ASTE FOR

F

OALS

, Y

EARLINGS AND

P

ONIES

ACTIVE CONSTITUENTS:

3.7 mg/g ABAMECTIN

46.2 mg/g PRAZIQUANTEL

For treatment and control of tapeworms and roundworms

(including arterial larval stages of Strongylus vulgaris and benzimidazole

resistant small strongyles), bots, and skin lesions caused by Habronema

and Draschia spp. (summer sores) and Onchocerca spp. microfilariae

(cutaneous onchocerciasis).

16.2 g

DIRECTIONS FOR USE:

At the recommended dose level of 1 mL/ 20 kg, EQUIMAX

®

300 Oral Paste for Foals, Yearlings

and Ponies controls the following parasites :

Tapeworms : Anoplocephala perfoliata, Anoplocephala magna, Paranoplocephala mammillana

(adult and immature, heads and segments).

Large Strongyles : Strongylus vulgaris (adults and arterial larval stages), Strongylus edentatus

(adults and tissue stages), Strongylus equinus (adults) and Triodontophorus spp. (adults).

Small Strongyles : Including benzimidazole resistant strains (adult and immature) Cyathostomum

spp., Cylicocyclus spp., Cylicostephanus spp., Cylicodontophorus spp., Gyalocephalus spp.

Pinworms : Oxyuris equi (adult and immature)

Ascarids : Parascaris equorum (adult and immature)

Hairworms : Trichostrongylus axei (adult)

Large Mouth Stomach Worms : Habronema muscae (adult)

Neck Threadworms : Onchocerca spp. (microfilariae)

Bots : Gasterophilus spp. (oral and gastric stages)

Lungworms : Dictyocaulus arnfieldi (adult and immature)

lntestinal Threadworms : Strongyloides westeri (adult).

EQUIMAX

®

300 Oral Paste for Foals, Yearlings and Ponies is also effective for control of skin

lesions

caused

Habronema

and

Draschia

spp.

cutaneous

larvae

(summer

sores),

Onchocerca spp, microfilariae (cutaneous onchocerciasis).

Dosage and Administration:

EQUIMAX

®

300 Oral Paste for Foals, Yearlings and Ponies is given orally at the recommended

dose level of 1mL/ 20 kg bodyweight. The contents of this syringe will treat one horse or pony at 300

kg bodyweight. Each weight marking on the syringe plunger will deliver 5.4 g of paste which is

sufficient to treat 100 kg bodyweight. Insert the syringe into the side of the horse's mouth in the gap

between the front and back teeth. Advance the plunger as far as it will go, press the plunger to the

chosen dosage, depositing the medication on the rear of the tongue. Immediately raise the horse's

head for a few seconds after dosing to ensure the full dose has been swallowed.

SUGGESTED PARASITE CONTROL PROGRAMME:

29 October, 1999

Primary – Plastic Bucket or Cardboard Box

Version # 4

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3 of 3

____________________________________________________________________________________________________________

All horses should be included in a regular parasite control programme with particular attention being

paid to mares, foals and yearlings. EQUIMAX

®

300 Oral Paste for Foals, Yearlings and Ponies is

highly effective against tapeworms and gastrointestinal, cutaneous, and pulmonary nematodes and

bots of horses of all ages. Regular treatment will reduce the chances of verminous arteritis and colic

caused by S.vulgaris. With its broad spectrum, EQUIMAX

®

300 Oral Paste for Foals, Yearlings

and Ponies is well suited to be the major product in a parasite control programme. Consult your

veterinarian for a control programme to meet your specific needs.

MEAT WITHHOLDING PERIOD:

DO NOT USE less than 28 days before slaughter for human consumption.

GENERAL INSTRUCTIONS:

Broad spectrum:

EQUIMAX

®

300 Oral Paste for Foals, Yearlings and Ponies kills all the important internal parasites

of horses including the arterial stages of S.vulgaris and tapeworms and bots, with a single, easy to

administer, dose. Because reinfection is common, treatment must be repeated routinely for effective

control.

Safety:

EQUIMAX

®

300 Oral Paste for Foals, Yearlings and Ponies has shown a wide safety margin at

the recommended dose level. It may be used in horses of all ages. Mares may be treated at any

stage of pregnancy. Stallions may be treated without adversely affecting their fertility.

SAFETY DIRECTIONS:

Poisonous if swallowed. May irritate the eyes and skin. Avoid contact with eyes and skin.

Wash hands after use.

FIRST AID:

If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131126;

New Zealand 03 474 7000. If swallowed and if more than 15 minutes from a hospital, induce

vomiting, preferably using Ipecac Syrup APF. If skin contact occurs, remove contaminated

clothing and wash skin thoroughly.

Additional information is listed in the Material Safety Data Sheet.

VIRBAC (AUSTRALIA) PTY. LIMITED

15 Pritchard Place, Peakhurst NSW 2210

PROTECTION OF FISH CRUSTACEANS AND THE ENVIRONMENT:

Free ABAMECTIN may adversely affect fish and certain waterborne organisms. Do not contaminate

dams, waterways or drains with this product or used container.

DISPOSAL:

Dispose of empty container and syringe by wrapping with paper and putting in garbage.

STORAGE: Store below 30ºC (Room Temperature) away from light.

® Registered Trade Mark of Virbac.

[B]:

CODE: (Carton)

EXP:

NRA: 52077/0799

93 12214 21410

VIRBAC (AUSTRALIA) PTY. LTD.

Document No:

Equimax 300.Doc

Revision B

MATERIAL SAFETY DATA SHEET

Product Name:

Equimax 300 Oral Paste for Foals, Yearlings and Ponies

Page: 1 of 5

Date of Issue

21 June, 2007

Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)

Section 1 - Identification of Chemical Product and Company

Company:

Virbac (Australia) Pty. Ltd

ABN 77 003 268 871

Address

15 Pritchard Place, Peakhurst, NSW 2210, Australia

Locked Bag 1000, Peakhurst Delivery Centre, Peakhurst, NSW 2210, Australia

Telephone:

(02) 9533 2000 or 1800 242 100

Fax:

(02) 9533 1522

Emergency phone

As above during business hours; answering machine after hours

Substance:

Abamectin and praziquantel are anti-parasitic agents.

Trade Name:

Equimax 300 Oral Paste for Foals, Yearlings and Ponies

Product Code:

EQMAX300; EQMAXSTD

Product Use:

For treatment and control of worms, bots and skin lesions on foals, yearlings and

ponies.

Creation Date:

December, 2002

Revision Date:

June, 2007

Section 2 - Hazards Identification

STATEMENT OF HAZARDOUS NATURE

This product is classified as:

Hazardous according to the criteria of ASCC Australia.

Not a Dangerous Good according to the Australian Dangerous Goods (ADG) Code.

Risk Phrases:

R22. Harmful if swallowed.

Safety Phrases:

S20. When using, do not eat or drink.

SUSDP Classification:

ADG Classification:

None allocated. Not a Dangerous Good.

UN Number:

None allocated

Emergency Overview

Physical Description & colour

: Smooth, thick cream coloured paste.

Odour:

Mild oatmeal odour.

Major Health Hazards:

Symptoms of poisoning observed in laboratory animals include pupil dilation, vomiting,

convulsions and/or tremors, and coma. Abamectin acts on mites by interfering with the nervous system. At very high

doses, it can affect mammals, causing symptoms of nervous system depression such as incoordination, tremors,

lethargy, excitation, and pupil dilation. Very high doses have caused death from respiratory failure. Abamectin is not

readily absorbed through skin. harmful if swallowed.

Potential Health Effects

See section 11 for Chronic exposure studies.

Inhalation

Short term exposure:

Available data indicates that this product is not harmful. In addition product is unlikely to

cause any discomfort or irritation.

Skin Contact:

Short term exposure:

Available data indicates that this product is not harmful. It should present no hazards in

normal use. However product may be mildly irritating, but is unlikely to cause anything more than mild discomfort

which should disappear once contact ceases.

Eye Contact:

Short term exposure

: Available data shows that this product is not harmful. However product may be mildly

irritating to eyes, but is unlikely to cause anything more than mild discomfort which should disappear once product is

removed.

Ingestion:

Short term exposure

: Available data shows that this product is harmful, but symptoms are not available. This

product is unlikely to cause any irritation problems in the short or long term.

VIRBAC (AUSTRALIA) PTY. LTD.

Document No:

Equimax 300.Doc

Revision B

MATERIAL SAFETY DATA SHEET

Product Name:

Equimax 300 Oral Paste for Foals, Yearlings and Ponies

Page: 2 of 5

Date of Issue

21 June, 2007

Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)

Carcinogen Status:

ASCC:

No significant ingredient is classified as carcinogenic by ASCC.

NTP:

No significant ingredient is classified as carcinogenic by NTP.

IARC:

No significant ingredient is classified as carcinogenic by IARC.

Section 3 - Composition/Information on Ingredients

Ingredients

CAS No

Conc,%

TWA (mg/m3)

STEL (mg/m3)

Abamectin

71751-41-2

0.37

not set

not set

Praziquantel

55268-74-1

not set

not set

Other non hazardous ingredients

secret

30-60

not set

not set

Water

7732-18-5

to 100

not set

not set

This is a commercial product whose exact ratio of components may vary slightly. Minor quantities of other non

hazardous ingredients are also possible.

The TWA exposure value is the average airborne concentration of a particular substance when calculated over a normal 8 hour working day for a 5

day working week. The STEL (Short Term Exposure Limit) is an exposure value that should not be exceeded for more than 15 minutes and should

not be repeated for more than 4 times per day. There should be at least 60 minutes between successive exposures at the STEL. The term "peak "is

used when the TWA limit, because of the rapid action of the substance, should never be exceeded, even briefly.

Section 4 - First Aid Measures

General Information:

You should call The Poisons Information Centre if you feel that you may have been poisoned, burned or irritated by

this product. The number is 13 1126 from anywhere in Australia (0800 764 766 in New Zealand) and is available at all

times. Have this MSDS with you when you call.

Inhalation:

First aid is not generally required. If in doubt, contact a Poisons Information Centre or a doctor.

Skin Contact:

Irritation is unlikely. However, if irritation does occur, flush with lukewarm, gently flowing water for 5

minutes or until chemical is removed.

Eye Contact:

No effects expected. If irritation does occur, flush contaminated eye(s) with lukewarm, gently flowing

water for 5 minutes or until the product is removed.

Ingestion:

If swallowed, do NOT induce vomiting. Wash mouth with water and contact a Poisons Information

Centre, or call a doctor.

Section 5 - Fire Fighting Measures

Fire and Explosion Hazards

: There is no risk of an explosion from this product under normal circumstances if it is

involved in a fire.

Fire decomposition products from this product may be toxic if inhaled. Take appropriate protective measures.

This product is likely to decompose only after heating to dryness, followed by further strong heating.

Extinguishing Media

: Not Combustible. Use extinguishing media suited to burning materials.

Fire Fighting

: If a significant quantity of this product is involved in a fire, call the fire brigade.

Flash point

:

Does not burn.

Upper Flammability Limit:

Does not burn.

Lower Flammability Limit:

Does not burn.

Autoignition temperature:

Not applicable - does not burn.

Flammability Class:

Does not burn.

Section 6 - Accidental Release Measures

Accidental release

: In the event of a major spill, prevent spillage from entering drains or water courses. As a

minimum, wear overalls, goggles and gloves. Suitable materials for protective clothing include rubber. Stop leak if

safe to do so, and contain spill. Absorb onto sand, vermiculite or other suitable absorbent material. If spill is too large

or if absorbent material is not available, try to create a dike to stop material spreading or going into drains or

waterways. Sweep up and shovel or collect recoverable product into labelled containers for recycling or salvage, and

dispose of promptly. Recycle containers wherever possible after careful cleaning. After spills, wash area preventing

runoff from entering drains. If a significant quantity of material enters drains, advise emergency services. This material

may be suitable for approved landfill. Ensure legality of disposal by consulting regulations prior to disposal.

Thoroughly launder protective clothing before storage or re-use. Advise laundry of nature of contamination when

sending contaminated clothing to laundry.

VIRBAC (AUSTRALIA) PTY. LTD.

Document No:

Equimax 300.Doc

Revision B

MATERIAL SAFETY DATA SHEET

Product Name:

Equimax 300 Oral Paste for Foals, Yearlings and Ponies

Page: 3 of 5

Date of Issue

21 June, 2007

Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)

Section 7 - Handling and Storage

Handling

: Keep exposure to this product to a minimum, and minimise the quantities kept in work areas. Check

Section 8 of this MSDS for details of personal protective measures, and make sure that those measures are followed.

The measures detailed below under "Storage" should be followed during handling in order to minimise risks to

persons using the product in the workplace. Also, avoid contact or contamination of product with incompatible

materials listed in Section 10.

Storage

: This product is a Scheduled Poison. Observe all relevant regulations regarding sale, transport and storage

of this class of poison. Make sure that containers of this product are kept tightly closed. Make sure that the product

does not come into contact with substances listed under "Materials to avoid" in Section 10. Some liquid preparations

settle or separate on standing and may require stirring before use. Check packaging - there may be further storage

instructions on the label.

Section 8 - Exposure Controls and Personal Protection

The following Australian Standards will provide general advice regarding safety clothing and equipment:

Respiratory equipment: AS/NZS 1715, Protective Gloves: AS 2161, Industrial Clothing: AS2919, Industrial Eye

Protection: AS1336 and AS/NZS 1337, Occupational Protective Footwear: AS/NZS2210.

Exposure Limits

TWA (mg/m

3

)

STEL (mg/m

3

)

Exposure limits have not been established by ASCC for any of the significant ingredients in this product.

The ADI for Abamectin is set at 0.0005mg/kg/day. The corresponding NOEL is set at 0.5mg/kg/day.

The ADI for Praziquantel is set at 0.02mg/kg/day. The corresponding NOEL is set at 20mg/kg/day. ADI means

Acceptable Daily Intake and NOEL means No-observable-effect-level. Values taken from Australian ADI List,

December 2006.

Ventilation:

No special ventilation requirements are normally necessary for this product. However make sure that

the work environment remains clean and that dusts are minimised.

Eye Protection:

Eye protection is not normally necessary when this product is being used. However, if in doubt,

wear suitable protective glasses or goggles.

Skin Protection:

The information at hand indicates that this product is not harmful and that normally no special skin

protection is necessary. However, we suggest that you routinely avoid contact with all chemical products and that you

wear suitable gloves (preferably elbow-length) when handling this product.

Protective Material Types:

There is no specific recommendation for any particular protective material type.

Respirator:

Usually, no respirator is necessary when using this product. However, if you have any doubts consult

the Australian Standard mentioned above.

Section 9 - Physical and Chemical Properties:

Physical Description & colour

Smooth, thick cream coloured paste.

Odour:

Mild oatmeal odour.

Boiling Point:

Approximately 100°C at 100kPa.

Freezing/Melting Point:

Approximately 0°C.

Volatiles:

Water component.

Vapour Pressure:

2.37 kPa at 20°C (water vapour pressure).

Vapour Density:

No data.

Specific Gravity:

1.07-1.11

Water Solubility:

Completely soluble in water.

pH:

5.0-6.0 (10% dispersion in water)

Volatility:

No data.

Odour Threshold:

No data.

Evaporation Rate:

No data.

Coeff Oil/water distribution

No data

Autoignition temp:

Not applicable - does not burn.

Section 10 - Stability and Reactivity

Reactivity:

This product is unlikely to react or decompose under normal storage conditions. However, if you have

any doubts, contact the supplier for advice on shelf life properties.

Conditions to Avoid:

This product should be kept in a cool place, preferably below 30°C.

Incompatibilities:

strong acids, strong bases, strong oxidising agents.

VIRBAC (AUSTRALIA) PTY. LTD.

Document No:

Equimax 300.Doc

Revision B

MATERIAL SAFETY DATA SHEET

Product Name:

Equimax 300 Oral Paste for Foals, Yearlings and Ponies

Page: 4 of 5

Date of Issue

21 June, 2007

Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)

Fire Decomposition:

Carbon dioxide, and if combustion is incomplete, carbon monoxide and smoke. Water.

Carbon monoxide poisoning produces headache, weakness, nausea, dizziness, confusion, dimness of vision,

disturbance of judgment, and unconsciousness followed by coma and death.

Polymerisation:

This product is unlikely to undergo polymerisation processes.

Section 11 - Toxicological Information

Toxicity:

Acute toxicity: Abamectin is highly toxic to arthropods and may be highly toxic to mammals as well.

Emulsifiable concentrate formulations may cause slight to moderate eye irritation and mild skin irritation. Symptoms of

poisoning observed in laboratory animals include pupil dilation, vomiting, convulsions and/or tremors, and coma.

Abamectin acts on insects by interfering with the nervous system. At very high doses, it can affect mammals, causing

symptoms of nervous system depression such as incoordination, tremors, lethargy, excitation, and pupil dilation. Very

high doses have caused death from respiratory failure. Abamectin is not readily absorbed through skin. Tests with

monkeys show that less than 1% of dermally applied abamectin was absorbed into the bloodstream through the skin.

Abamectin does not cause allergic skin reactions. The oral LD

for abamectin in rats is 10 mg/kg, and in mice ranges

from 14 mg/kg to greater than 80 mg/kg. The dermal LD

for technical abamectin in rats and rabbits is greater than

330 mg/kg.

Chronic toxicity: In a 1-year study with dogs given oral doses of abamectin, dogs at the 0.5 and 1 mg/kg/day doses

exhibited pupil dilation, weight loss, lethargy, tremors, and recumbency. Similar results were seen in a 2-year study

with rats fed 0.75, 1.5, or 2 mg/kg/day. Rats at all the dosage levels exhibited body weight gains significantly higher

than the controls. A few individuals in the high dose group exhibited tremors. When mice were fed 8 mg/kg/day for 94

weeks, the males developed dermatitis and changes in blood formation in the spleen, while females exhibited tremors

and weight loss.

Reproductive effects: Rats given 0.40 mg/kg/day of abamectin had increased stillbirths, decreased pup viability,

decreased lactation, and decreased pup weights. These data suggest that abamectin may have the potential to cause

reproductive effects at high enough doses.

Teratogenic effects: Abamectin produced cleft palate in the offspring of treated mice and rabbits, but only at doses

that were also toxic to the mothers. There were no birth defects in the offspring of rats given up to 1 mg/kg/day.

Abamectin is unlikely to cause teratogenic effects except at doses toxic to the mother.

Mutagenic effects: Abamectin does not appear to be mutagenic. Mutagenicity tests in live rats and mice were

negative. Abamectin was shown to be nonmutagenic in the Ames test.

Carcinogenic effects: Abamectin is not carcinogenic in rats or mice. The rats were fed dietary doses of up to 2

mg/kg/day for 24 months, and the mice were up to 8 mg/kg/day for 22 months. These represent the maximum

tolerated doses.

Organ toxicity: Animal studies indicate that abamectin may affect the nervous system.

Fate in humans and animals: Tests with laboratory animals show that ingested avermectin B1a is not readily

absorbed into the bloodstream by mammals and that it is rapidly eliminated from the body within 2 days via the

faeces. Rats given single oral doses of avermectin B1a excreted 69 to 82% of the dose unchanged in the faeces. The

average half-life of avermectin B1a in rat tissue is 1.2 days. Lactating goats given daily oral doses for 10 days

excreted 89% of the administered avermectin, mainly in the faeces. Less than 1% was recovered in the urine.

Section 12 - Ecological Information

Effects on birds: Abamectin is practically nontoxic to birds. The LD

for abamectin in bobwhite quail is >2000 mg/kg.

The dietary LC

is 3102 ppm in bobwhite quail. There were no adverse effects on reproduction when mallard ducks

were fed dietary doses of 3, 6, or 12 ppm for 18 weeks.

Effects on aquatic organisms: Abamectin is highly toxic to fish and extremely toxic to aquatic invertebrates. Its LC

(96-hour) is 0.003 mg/L in rainbow trout, 0.0096 mg/L in bluegill sunfish, 0.015 mg/L in sheepshead minnows, 0.024

mg/L in channel catfish, and 0.042 mg/L in carp. Its 48-hour LC

in Daphnia magna, a small freshwater crustacean, is

0.003 mg/L. The 96-hour LC

for abamectin is 0.0016 mg/L in pink shrimp, 430 mg/L in eastern oysters, and 153

mg/L in blue crab. While highly toxic to aquatic organisms, actual concentrations of abamectin in surface waters

adjacent to treated areas are expected to be low. Abamectin did not bioaccumulate in bluegill sunfish exposed to

0.099 μg/L for 28 days in a flow-through tank. The levels in fish were from 52 to 69 times the ambient water

concentration, indicating that abamectin does not accumulate or persist in fish.

Effects on other organisms: Abamectin is highly toxic to bees, with a 24-hour contact LC

of 0.002 μg/bee and an

oral LD

of 0.009 μg/bee.

Breakdown in soil and groundwater: Abamectin is rapidly degraded in soil. At the soil surface, it is subject to rapid

photodegradation, with half-lives of 8 hours to 1 day reported. When applied to the soil surface and not shaded, its

soil half-life is about 1 week. Under dark, aerobic conditions, the soil half-life was 2 weeks to 2 months. Loss of

abamectin from soils is thought to be due to microbial degradation. The rate of degradation was significantly

decreased under anaerobic conditions. Because abamectin is nearly insoluble in water and has a strong tendency to

bind to soil particles, it is immobile in soil and unlikely to leach or contaminate groundwater. Compounds produced by

the degradation of abamectin are also immobile and unlikely to contaminate groundwater.

VIRBAC (AUSTRALIA) PTY. LTD.

Document No:

Equimax 300.Doc

Revision B

MATERIAL SAFETY DATA SHEET

Product Name:

Equimax 300 Oral Paste for Foals, Yearlings and Ponies

Page: 5 of 5

Date of Issue

21 June, 2007

Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)

Breakdown in water: Abamectin is rapidly degraded in water. After initial distribution, its half-life in artificial pond

water was 4 days. Its half-life in pond sediment was 2 to 4 weeks. It undergoes rapid photodegradation, with a half-life

of 12 hours in water. When tested at pH levels common to surface and groundwater (pH 5, 7, and 9), abamectin did

not hydrolyze.

Breakdown in vegetation: Plants do not absorb abamectin from the soil. Abamectin is subject to rapid degradation

when present as a thin film, as on treated leaf surfaces. Under laboratory conditions and in the presence of light, its

half-life as a thin film was 4 to 6 hours.

Section 13 - Disposal Considerations

Disposal:

Containers should be emptied as completely as practical before disposal. If possible, recycle containers

either in-house or send to recycle company. If this is not practical, send to a commercial waste disposal site. This

product should be suitable for landfill. However, check with local Waste Disposal Authority before sending there. Note

that product properties may have been changed in use, significantly altering it's suitability for landfill. Please do NOT

dispose into sewers or waterways.

Section 14 - Transport Information

ADG Code:

This product is not classified as a Dangerous Good. No special transport conditions are necessary

unless required by other regulations.

Section 15 - Regulatory Information

AICS:

All of the significant ingredients in this formulation are to be found in the public AICS Database.

Section 16 - Other Information

Much of the Information in this MSDS came from Extoxnet, a Pesticide Information Project of Cooperative Extension

Offices of Cornell University, Oregon State University, the University of Idaho, and the University of California at Davis

and the Institute for Environmental Toxicology, Michigan State University.

This MSDS contains only safety-related information. For other data see product literature.

Contact point:

Technical Manager, QA Manager or R&D Director

Telephone

(02) 9533 2000 or 1800 242 100

Fax

(02) 9533 1522

Acronyms:

ADG Code

Australian Code for the Transport of Dangerous Goods by Road and Rail

AICS

Australian Inventory of Chemical Substances

CAS number

Chemical Abstracts Service Registry Number

Hazchem Number

Emergency action code of numbers and letters that provide information to

emergency services especially firefighters

IARC

International Agency for Research on Cancer

ASCC

Office of the Australian Safety and Compensation Council

NOS

Not otherwise specified

NTP

National Toxicology Program (USA)

R-Phrase

Risk Phrase

SUSDP

Standard for the Uniform Scheduling of Drugs & Poisons

UN Number

United Nations Number

THIS MSDS SUMMARISES OUR BEST KNOWLEDGE OF THE HEALTH AND SAFETY HAZARD INFORMATION OF THE PRODUCT AND

HOW TO SAFELY HANDLE AND USE THE PRODUCT IN THE WORKPLACE. EACH USER MUST REVIEW THIS MSDS IN THE CONTEXT OF

HOW THE PRODUCT WILL BE HANDLED AND USED IN THE WORKPLACE.

IF CLARIFICATION OR FURTHER INFORMATION IS NEEDED TO ENSURE THAT AN APPROPRIATE RISK ASSESSMENT CAN BE MADE,

THE USER SHOULD CONTACT THIS COMPANY SO WE CAN ATTEMPT TO OBTAIN ADDITIONAL INFORMATION FROM OUR SUPPLIERS

OUR RESPONSIBILITY FOR PRODUCTS SOLD IS SUBJECT TO OUR STANDARD TERMS AND CONDITIONS, A COPY OF WHICH IS SENT

TO OUR CUSTOMERS AND IS ALSO AVAILABLE ON REQUEST.

Please read all labels carefully before using product.

This MSDS is prepared in accord with the ASCC document 'National Code of Practice for the

Preparation of Material Safety Data Sheets' 2nd Edition [NOHSC:2011(2003)]

Copyright © Kilford & Kilford Pty. Ltd., June, 2007.

http://www.kilford.com.au/ Phone (02) 9251 4532

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