DADAL VASODILATOR INJECTION FOR HORSES

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

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Active ingredient:
DI-ISOPROPYLAMINE DICHLOROACETATE; SODIUM GLUCONATE
Available from:
RANVET PTY. LIMITED
INN (International Name):
sodium gluconate(19mg/mL)+di-isopropylamine dichloroac(20mg/mL)
Pharmaceutical form:
PARENTERAL LIQUID/SOLUTION/SUSPENSION
Composition:
DI-ISOPROPYLAMINE DICHLOROACETATE UNGROUPED Active 20.0 mg/ml; SODIUM GLUCONATE MINERAL-SODIUM-SALT Active 19.0 mg/ml
Units in package:
50mL
Class:
VM - Veterinary Medicine
Therapeutic group:
HORSE | COLT | DONKEY | ENDURANCE HORSE | FILLY | FOAL | GELDING | HIGH PERFORMANCE HORSES | HORSES AT STUD | MARE | PACER | POL
Therapeutic area:
CARDIOVASCULAR SYSTEM
Therapeutic indications:
VASCULAR SYSTEM REACTANT | CARDIAC STIMULANT | CORONARY VASODILATOR | NAVICULAR DISEASE | REACTANTS ON VASCULAR SYSTEM | RESPIRATORY STIMULANT | TICK PARALYSIS | VASCULAR SYSTEM | VASODILATION
Product summary:
Poison schedule: 4; Withholding period: WHP:MEAT: Not to be used in horses that may be slaughtered for human consumpt ion.; Host/pest details: HORSE: [VASCULAR SYSTEM REACTANT]; Vasodilator Injection for horses.
Authorization status:
Registered
Authorization number:
51251
Authorization date:
2019-07-01

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RANVET DADAL

ChemWatch Material Safety Data Sheet

CHEMWATCH 4966-81

For Workplace - Small Volume Use Only.

Issue Date: Thu 6-Mar-2008

CD 2004/3 Page 1 of 8

Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

RANVET DADAL

SYNONYMS

PRODUCT USE

Vasodilator injectable for horses.

SUPPLIER

Company: Ranvet Pty Ltd (ACN: 001 606 033)

Address:

10-12 Green Street

East Botany

NSW, 2019

Telephone: +61 2 9666 1744

Emergency Tel: +61 44 18 493 533 A/H

Fax: 02 9666 1755

Section 2 - HAZARDS IDENTIFICATION

STATEMENT OF HAZARDOUS NATURE

NON-HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS.

According to the Criteria of NOHSC, and the ADG Code.

POISONS SCHEDULE

RISK

SAFETY

Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS

NAME

CAS RN

diisopropylamine dichloroacetate

660-27-5

performance additives nonhazardous

<1

water

7732-18-5

>60

continued...

RANVET DADAL

ChemWatch Material Safety Data Sheet

CHEMWATCH 4966-81

For Workplace - Small Volume Use Only.

Issue Date: Thu 6-Mar-2008

CD 2004/3 Page 2 of 8

Section 4 - FIRST AID MEASURES

SWALLOWED

If poisoning occurs, contact a doctor or Poisons Information Centre.

If this product comes in contact with eyes:

- Wash out immediately with water.

- If irritation continues, seek medical attention.

- Removal of contact lenses after an eye injury should only be undertaken by

skilled personnel.

SKIN

If skin or hair contact occurs:

- Flush skin and hair with running water (and soap if available).

- Seek medical attention in event of irritation.

INHALED

- If fumes or combustion products are inhaled remove from contaminated area.

- Other measures are usually unnecessary.

NOTES TO PHYSICIAN

Treat symptomatically.

Section 5 - FIRE FIGHTING MEASURES

EXTINGUISHING MEDIA

The product contains a substantial proportion of water, therefore there are no

restrictions on the type of extinguishing media which may be used. Choice of

extinguishing media should take into account surrounding areas.

Though the material is non-combustible, evaporation of water from the mixture,

caused by the heat of nearby fire, may produce floating layers of combustible

substances.

In such an event consider:

- foam

- dry chemical powder

- carbon dioxide

FIRE FIGHTING

- Alert Fire Brigade and tell them location and nature of hazard.

- Wear breathing apparatus plus protective gloves for fire only.

- Prevent, by any means available, spillage from entering drains or water

courses.

- Use fire fighting procedures suitable for surrounding area.

- DO NOT approach containers suspected to be hot.

continued...

RANVET DADAL

ChemWatch Material Safety Data Sheet

CHEMWATCH 4966-81

For Workplace - Small Volume Use Only.

Issue Date: Thu 6-Mar-2008

CD 2004/3 Page 3 of 8

Section 5 - FIRE FIGHTING MEASURES ...

- Cool fire exposed containers with water spray from a protected location.

- If safe to do so, remove containers from path of fire.

- Equipment should be thoroughly decontaminated after use.

FIRE/EXPLOSION HAZARD

- Non combustible.

- Not considered to be a significant fire risk.

- Expansion or decomposition on heating may lead to violent rupture of

containers.

- Decomposes on heating and may produce toxic fumes of carbon monoxide (CO).

- May emit acrid smoke.

Decomposition may produce toxic fumes of

carbon dioxide (CO2)

nitrogen oxides (NOx)

FIRE INCOMPATIBILITY

None known.

HAZCHEM

None

Section 6 - ACCIDENTAL RELEASE MEASURES

EMERGENCY PROCEDURES

MINOR SPILLS

- Clean up all spills immediately.

- Avoid breathing vapours and contact with skin and eyes.

- Control personal contact by using protective equipment.

- Contain and absorb spill with sand, earth, inert material or vermiculite.

- Wipe up.

- Place in a suitable labelled container for waste disposal.

Personal Protective Equipment advice is contained in Section 8 of the MSDS.

Section 7 - HANDLING AND STORAGE

PROCEDURE FOR HANDLING

- Limit all unnecessary personal contact.

- Wear protective clothing when risk of exposure occurs.

- Use in a well-ventilated area.

- When handling DO NOT eat, drink or smoke.

- Always wash hands with soap and water after handling.

- Avoid physical damage to containers.

continued...

RANVET DADAL

ChemWatch Material Safety Data Sheet

CHEMWATCH 4966-81

For Workplace - Small Volume Use Only.

Issue Date: Thu 6-Mar-2008

CD 2004/3 Page 4 of 8

Section 7 - HANDLING AND STORAGE ...

- Use good occupational work practice.

- Observe manufacturer's storing and handling recommendations.

SUITABLE CONTAINER

Ampoule. Vial.

STORAGE INCOMPATIBILITY

None known

STORAGE REQUIREMENTS

- Store in original containers.

- Keep containers securely sealed.

- Store in a cool, dry, well-ventilated area.

- Store away from incompatible materials and foodstuff containers.

- Protect containers against physical damage and check regularly for leaks.

- Observe manufacturer's storing and handling recommendations.

Store below 25 deg.C.

Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION

EXPOSURE CONTROLS

None assigned.

INGREDIENT DATA

DIISOPROPYLAMINE DICHLOROACETATE:

Airborne particulate or vapour must be kept to levels as low as is practicably

achievable given access to modern engineering controls and monitoring hardware.

Biologically active compounds may produce idiosyncratic effects which are

entirely unpredictable on the basis of literature searches and prior clinical

experience (both recent and past).

WATER:

No exposure limits set by NOHSC or ACGIH

PERSONAL PROTECTION

- Safety glasses with side shields; or as required,

- Chemical

goggles.

- Contact lenses pose a special

hazard; soft lenses may absorb irritants and all

lenses concentrate them.

continued...

RANVET DADAL

ChemWatch Material Safety Data Sheet

CHEMWATCH 4966-81

For Workplace - Small Volume Use Only.

Issue Date: Thu 6-Mar-2008

CD 2004/3 Page 5 of 8

Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION ...

HANDS/FEET

Wear general

protective gloves, eg. light weight rubber gloves.

OTHER

No special

equipment needed when handling small

quantities.

OTHERWISE:

- Overalls.

- Barrier cream.

- Eyewash unit.

GLOVE SELECTION INDEX

Glove selection is based on a modified presentation of the:

"Forsberg Clothing Performance Index".

The effect(s) of the following substance(s) are taken into account in the

computer-generated selection:

Substance

________________________________________

water

BUTYL

NEOPRENE

VITON

NATURAL RUBBER

* CPI - Chemwatch Performance Index

A: Best Selection

B: Satisfactory; may degrade after 4 hours continuous immersion

C: Poor to Dangerous Choice for other than short term immersion

NOTE: As a series of factors will

influence the actual

performance of the glove,

a final

selection must be based on detailed observation. -

* Where the glove is to be used on a short term, casual

or infrequent basis,

factors such as "feel" or convenience (e.g. disposability),

may dictate a choice

of gloves which might otherwise be unsuitable following long-term or frequent

use. A qualified practitioner should be consulted.

The local

concentration of material, quantity and conditions of use determine

the type of personal

protective equipment required. For further information

consult site specific CHEMWATCH data (if available), or your Occupational

Health and Safety Advisor.

ENGINEERING CONTROLS

General

exhaust is adequate under normal

operating conditions. If risk of

overexposure exists, wear SAA approved respirator. Correct fit is essential

obtain adequate protection. Provide adequate ventilation in warehouse or closed

storage areas.

continued...

RANVET DADAL

ChemWatch Material Safety Data Sheet

CHEMWATCH 4966-81

For Workplace - Small Volume Use Only.

Issue Date: Thu 6-Mar-2008

CD 2004/3 Page 6 of 8

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

APPEARANCE

Clear liquid; mixes with water.

PHYSICAL PROPERTIES

Liquid.

Mixes with water.

Molecular Weight: Not Applicable

Boiling Range (°C): Not Available

Melting Range (°C): Not Available

Specific Gravity (water=1): 1.0

Solubility in water (g/L): Miscible

pH (as supplied): Not Available

pH (1% solution): Not Available

Vapour Pressure (kPa): Not Available

Volatile Component (%vol): Not Available

Evaporation Rate: Not Available

Relative Vapour Density (air=1): Not Available

Flash Point (°C): Not Applicable

Lower Explosive Limit (%): Not Applicable

Upper Explosive Limit (%): Not Applicable

Autoignition Temp (°C): Not Applicable

Decomposition Temp (°C): Not Available

State: Liquid

Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION

CONDITIONS CONTRIBUTING TO INSTABILITY

Product is considered stable and hazardous polymerisation will not occur.

Section 11 - TOXICOLOGICAL INFORMATION

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

(No Oral LD50, any animal species) The material has NOT been classified by EC

Directives or other classification systems as "harmful by ingestion". This is

because of the lack of corroborating animal or human evidence. The material may

still be damaging to the health of the individual, following ingestion,

especially where pre-existing organ (eg. liver, kidney) damage is evident.

Present definitions of harmful or toxic substances are generally based on doses

producing mortality rather than those producing morbidity (disease, ill-health).

Gastrointestinal tract discomfort may produce nausea and vomiting. In an

occupational setting however, ingestion of insignificant quantities is not

thought to be cause for concern.

Although the liquid is not thought to be an irritant (as classified by EC

Directives), direct contact with the eye may produce transient discomfort

characterised by tearing or conjunctival redness (as with windburn).

continued...

RANVET DADAL

ChemWatch Material Safety Data Sheet

CHEMWATCH 4966-81

For Workplace - Small Volume Use Only.

Issue Date: Thu 6-Mar-2008

CD 2004/3 Page 7 of 8

Section 11 - TOXICOLOGICAL INFORMATION ...

SKIN

The material is not thought to produce adverse health effects or skin irritation

following contact (as classified by EC Directives using animal models).

Nevertheless, good hygiene practice requires that exposure be kept to a minimum

and that suitable gloves be used in an occupational setting.

INHALED

Not normally a hazard due to non-volatile nature of product

CHRONIC HEALTH EFFECTS

Long-term exposure to the product is not thought to produce chronic effects adverse to the

health (as classified by EC Directives using animal models); nevertheless exposure by all

routes should be minimised as a matter of course.

Ranvet Dadal

Not available. Refer to individual

constituents.

unless otherwise specified data extracted from RTECS - Register of Toxic Effects

of Chemical

Substances

DIISOPROPYLAMINE DICHLOROACETATE:

TOXICITY

IRRITATION

Intraperitoneal

(rat) LD50: 840 mg/kg

reported

Oral

(mouse) LD50: 1700 mg/kg

Intraperitoneal

(mouse) LD50: 750 mg/kg

Subcutaneous (mouse) LD50: 1330 mg/kg

Intravenous (mouse) LD50: 235 mg/kg

Intramuscular (mouse) LD50: 1800 mg/kg

NOTE: Substance has been shown to be mutagenic in at least one assay, or belongs

to a family of chemicals producing damage or change to cellular DNA.

Convulsions, cyanosis, somnolence,

tremor recorded.

WATER:

No significant acute toxicological

data identified in literature search.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS

- Recycle wherever possible or consult manufacturer for recycling options.

- Consult State Land Waste Management Authority for disposal.

- Bury residue in an authorised landfill.

- Recycle containers if possible, or dispose of in an authorised landfill.

continued...

RANVET DADAL

ChemWatch Material Safety Data Sheet

CHEMWATCH 4966-81

For Workplace - Small Volume Use Only.

Issue Date: Thu 6-Mar-2008

CD 2004/3 Page 8 of 8

Section 14 - TRANSPORTATION INFORMATION

Shipping Name:

None

Dangerous Goods Class: None

UN/NA Number: None

ADR Number: None

Packing Group: None

Labels Required:

Additional Shipping Information:

International Transport Regulations:

IMO: None

HAZCHEM

None

Section 15 - REGULATORY INFORMATION

POISONS SCHEDULE

REGULATIONS

No data available for diisopropylamine dichloroacetate as (CAS:

660-27-5). (CAS: 7732-18-5).

Section 16 - OTHER INFORMATION

This document is copyright. Apart from any fair dealing for the purposes of

private study, research, review or criticism, as permitted under the Copyright

Act, no part may be reproduced by any process without written permission from

CHEMWATCH. TEL (+61 3) 9572 4700.

Issue Date: Thu 6-Mar-2008

Print Date:

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